Correlations between serum levels of microRNA-148a-3p and microRNA-485-5p and the progression and recurrence of prostate cancer

Table 2 The levels of miR-148a-3p and miR-485-5p in preoperative serum of PCa patients

Parameters	Number (n)	miR-148a-3p	t	P	miR-485-5p	t	P
Age			0.525	0.584		0.952	0.350
≥ 60 years	127	4.85 ± 1.66			1.12 ± 0.54
< 60 years	71	4.73 ± 1.58			1.18 ± 0.41
Index lesion diameter			0.341	0.772		1.525	0.080
No index	103	4.85 ± 1.63			1.10 ± 0.44
≤ 7 mm	95	4.77 ± 1.82			1.18 ± 0.51
PSA level			0.711	0.500		1.915	0.083
> 10ng/mL	165	4.85 ± 2.12			1.11 ± 0.51
≤ 10ng/mL	33	4.66 ± 1.98			1.32 ± 0.62
Gleason score			7.520	< 0.001		17.58	< 0.001
< 7 points	143	3.98 ± 1.25			1.40 ± 0.58
≥ 7 points	55	7.05 ± 3.47			0.52 ± 0.23
TNM staging			7.113	< 0.001		18.225	< 0.001
cT1-2a	121	4.31 ± 2.01			4.02 ± 1.25
cT2b and higher	77	8.52 ± 2.28			0.42 ± 0.28

Data are shown as means ± SD. Result of student’s t-test. P < 0.05 is considered to be significant

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