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Table 3 Predictors of biochemical recurrence-free survival in patients with Nadir PSA ≥ 0.06 ng/mL

From: Adjusting the duration of androgen deprivation therapy (ADT) based on nadir PSA for high risk localized prostate cancer patients treated with definitive external beam radiation therapy and ADT

Factors

Univariate analysis

Multivariate analysis

HR (95% CI)

P value

HR (95% CI)

P value

Age (≤ 70 versus > 70 years)

1.248 (0.443–3.514)

0.675

1.178 (0.209–6.622)

0.853

T stage (T1-2 versus T3–4)

1.342 (0.461–3.908)

0.590

2.848 (0.515–15.747)

0.230

Gleason Score (≤ 7 versus 8–10)

2.118 (0.595–7.537)

0.247

3.018 (0.696–13.090)

0.140

PSA at presentation (≤ 20 versus > 20 ng/mL)

0.939 (0.310–2.840)

0.911

1.543 (0.412–5.787)

0.520

Total ADT duration*

0.319 (0.110–0.921)

0.035

0.306 (0.099–0.946)

0.040

  1. *Comparing the use of ADT for at least 18 months versus less than 18 months