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Table 2 Baseline clinical characteristics of patients diagnosed as urothelial bladder cancer with distant metastasis

From: Constructing and validating nomograms to predict risk and prognostic factors of distant metastasis in urothelial bladder cancer patients: a population-based retrospective study

 

Training

group(N = 1199)

Validation

group(N = 515)

Overall

(N = 1714)

X2

P

Age, years

   

2.442

0.486

 < 50

49 (4.1%)

25 (4.9%)

74 (4.3%)

  

 50–59

190 (15.8%)

73 (14.2%)

263 (15.3%)

  

 60–69

303 (25.3%)

119 (23.1%)

422 (24.6%)

  

 > 69

657 (54.8%)

298 (57.9%)

955 (55.7%)

  

Sex

   

0.057

0.811

 Female

350 (29.2%)

154 (29.9%)

504 (29.4%)

  

 Male

966 (72.1%)

401 (69.7%)

1367 (71.4%)

  

Race

   

Fisher

0.268

 American Indian/Alaska Native

2 (0.2%)

1 (0.2%)

3 (0.2%)

  

 Asian or Pacific Islander

44 (3.7%)

29 (5.6%)

73 (4.3%)

  

 Black

99 (8.3%)

40 (7.8%)

139 (8.1%)

  

 White

1054 (87.9%)

445 (86.4%)

1499 (87.5%)

  

Grade

   

Fisher

0.596

 I

9 (0.8%)

3 (0.6%)

12 (0.7%)

  

 II

42 (3.5%)

12 (2.3%)

54 (3.2%)

  

 III

369 (30.8%)

155 (30.1%)

524 (30.6%)

  

 IV

779 (65.0%)

345 (67.0%)

1124 (65.6%)

  

T

   

0.319

0.572

 Ta/Tis/T1

181 (15.1%)

84 (16.3%)

265 (15.5%)

  

 T2/T3/T4

1018 (84.9%)

431 (83.7%)

1449 (84.5%)

  

N

   

Fisher

0.670

 N0

708 (59.0%)

303 (58.8%)

1011 (59.0%)

  

 N1

209 (17.4%)

100 (19.4%)

309 (18.0%)

  

 N2

272 (22.7%)

107 (20.8%)

379 (22.1%)

  

 N3

10 (0.8%)

5 (1.0%)

15 (0.9%)

  

Histologic type

(transitional cell cancer)

   

Fisher

0.593

 NOS (8120)

782 (65.2%)

321 (62.3%)

1103 (64.4%)

  

 Spindle cells (8122)

23 (1.9%)

8 (1.6%)

31 (1.8%)

  

 Papillary (8130)

386 (32.2%)

183 (35.5%)

569 (33.2%)

  

 Micropapillary (8131)

8 (0.7%)

3 (0.6%)

11 (0.6%)

  

Tumor size, mm

   

1.259

0.739

 <30

151 (12.6%)

73 (14.2%)

224 (13.1%)

  

 30–49

354 (29.5%)

153 (29.7%)

507 (29.6%)

  

 50–99

610 (50.9%)

258 (50.1%)

868 (50.6%)

  

 >99

84 (7.0%)

31 (6.0%)

115 (6.7%)

  

Surgery

   

< 0.01

1

 No

55 (4.6%)

23 (4.5%)

78 (4.6%)

  

 Yes

1144 (95.4%)

492 (95.5%)

1636 (95.4%)

  

Chemotherapy

   

0.475

0.491

 No

554 (46.2%)

248 (48.2%)

802 (46.8%)

  

 Yes

645 (53.8%)

267 (51.8%)

912 (53.2%)

  

Radiotherapy

   

0.153

0.696

 No

931 (77.6%)

459 (79.8%)

1516 (79.2%)

  

 Yes

268 (22.4%)

110 (21.4%)

378 (22.1%)