Table 3 Univariate and multivariate COX regression analysis for OS in the training sets

Age

1.028

1.02–1.037

 < 0.001*

1.027

1.018–1.036

 < 0.001*

Sex

 Female

Ref

 Male

0.949

0.805–1.119

0.532

Race

 White

Ref

 Black

0.848

0.579–1.241

0.396

 Other

1.050

0.823–1.339

0.696

Marital status

 Married

Ref

 Divorced/widowed/Separated

1.269

1.038–1.549

0.020*

1.114

0.907–1.367

0.302

 Unmarried/Single

1.282

0.975–1.685

0.076

1.374

1.039–1.816

0.026*

Primary Site

 Renal Pelvis

Ref

 Ureter

1.003

0.848–1.186

0.973

Grade

 Grade I

Ref

 Grade II

1.101

0.545–2.224

0.788

 Grade III

1.409

0.746–2.658

0.290

 Grade IV

1.161

0.618–2.177

0.642

T Stage

 T1

Ref

 T2

0.826

0.581–1.172

0.284

1.064

0.744–1.519

0.735

 T3

1.084

0.847–1.387

0.520

1.349

1.044–1.743

0.022*

 T4

2.405

1.819–3.180

 < 0.001*

2.309

1.721–3.097

 < 0.001*

N Stage

 N0

Ref

 N1

1.880

1.542–2.292

 < 0.001*

1.284

1.035–1.593

0.023*

 N2

2.013

1.633–2.482

 < 0.001*

1.354

1.082–1.695

0.008*

M Stage

 M0

Ref

 M1

3.172

2.609–3.857

 < 0.001*

1.985

1.579–2.495

 < 0.001*

Radiation

 No/Unknown

Ref

 Yes

1.241

0.174–8.83

0.829

Surgical methods of the primary site

 No

Ref

 Local Mass resection/destruction

0.442

0.287–0.679

 < 0.001*

0.647

0.412–1.016

0.059

 Partial nephrectomy/ureterectomy

0.224

0.156–0.320

 < 0.001*

0.445

0.301–0.660

 < 0.001*

 Radical nephroureterectomy

0.221

0.171–0.284

 < 0.001*

0.380

0.283–0.509

 < 0.001*

 Radical nephrectomy

06.35

0.273–0.464

 < 0.001*

0.485

0.364–0.646

 < 0.001*

Surgery of Lymph nodes (LNs)

 No

Ref

 1 to 3 regional LNs removed

0.994

0.810–1.219

0.957

 4 or more regional LNs removed

0.830

0.672–1.025

0.083