Table 4 Multivariate Cox regression analyses on recurrence-free survival of urothelial carcinoma, intravesical recurrence and upper tract recurrence in patients between three groups, history of urothelial cancers (UTUC or bladder) vs. history of non-urothelial cancers vs. no history of any cancer

Smoke

0.058

0.695

0.312

No

Reference

Reference

Reference

Yes

1.416

(0.988–2.029)

0.993

(0.657–1.323)

1.298

(0.783–2.154)

Gender

0.102

0.540

0.084

Female

Reference

Reference

Reference

Male

0.754

(0.537–1.058)

1.121

(0.778–1.616)

0.660

(0.412–1.057)

Previous malignancy

0.151

0.013*

0.013*

Non-HPM

Reference

Reference

Reference

Uro-HPM

1.408

(0.985–2.014)

0.061

0.981

(0.641–1.502)

0.931

1.938

(1.214–3.095)

0.006**

Non-uro-HPM

1.229

(0.794–1.901)

0.355

1.810

(1.206–2.719)

0.004**

0.874

(0.430–1.777)

0.710

pT Stage

0.012*

0.760

0.139

Ta/Tis/T1

Reference

Reference

Reference

T2-4

1.598

(1.111-2.300)

1.059

(0.732–1.534)

0.668

(0.391–1.140)

Tumor Grade

0.419

0.537

0.013*

G1-2

Reference

Reference

Reference

G3

0.867

(0.613–1.226)

0.891

(0.617–1.286)

1.916

(1.145–3.204)