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Pre-clinical and basic research

Section edited by Prof. Kenneth Iczkowski 

This section considers articles describing all aspects of pre-clinical and basic research in the field of urology. This section covers a wide range of methodologies and study designs, including the identification of the molecular underpinnings of urological disease, and the application of this knowledge to clinical practice. Submissions describing clinical research should be directed to the sub-discipline specific sections.

  1. Activation of mast cells plays an important role in the pathogenesis of bladder pain syndrome/interstitial cystitis (BPS/IC). Histamine, a mast cell-derived mediators, induced inflammation and hypersensitivity...

    Authors: Hui Shan, Er-Wei Zhang, Peng Zhang, Xiao-Dong Zhang, Ning Zhang, Peng Du and Yong Yang

    Citation: BMC Urology 2019 19:115

    Content type: Research article

    Published on:

  2. Chronic inflammation is thought to be a major causative factor for the development of benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS). Tadalafil, a phosphodiesterase type 5 inhibitor...

    Authors: Mikio Sugimoto, Xia Zhang, Nobufumi Ueda, Hiroyuki Tsunemori, Rikiya Taoka, Yusi Hayashida, Hiromi Hirama, Yasuyuki Miyauchi, Yuki Matsuoka, Hirohito Naito, Yu Osaki and Yosiyuki Kekehi

    Citation: BMC Urology 2019 19:99

    Content type: Research article

    Published on:

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