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Pre-clinical and basic research

Section edited by Prof. Kenneth Iczkowski 

This section considers articles describing all aspects of pre-clinical and basic research in the field of urology. This section covers a wide range of methodologies and study designs, including the identification of the molecular underpinnings of urological disease, and the application of this knowledge to clinical practice. Submissions describing clinical research should be directed to the sub-discipline specific sections.

  1. RNA sequencing data is providing abundant information about the levels of dysregulation of genes in various tumors. These data, as well as data based on older microarray technologies have enabled the identific...

    Authors: Sinisa Simonovic, Christian Hinze, Kai M. Schmidt-Ott, Jonas Busch, Monika Jung, Klaus Jung and Anja Rabien

    Citation: BMC Urology 2020 20:7

    Content type: Research article

    Published on:

  2. The aim of the present study was to establish an animal model of Yang-Monti ileal ureter-bladder anastomosis and Yang-Monti ileal ureter-ureteral anastomosis and compare the advantages and disadvantages of the...

    Authors: Wang Zhenxing, Sun Zhaolin, Yang Xiushu, Luo Guangheng, Tian Ye, Shen Lei, Su Zhiyong and Liu Hongming

    Citation: BMC Urology 2019 19:129

    Content type: Research article

    Published on:

  3. Activation of mast cells plays an important role in the pathogenesis of bladder pain syndrome/interstitial cystitis (BPS/IC). Histamine, a mast cell-derived mediators, induced inflammation and hypersensitivity...

    Authors: Hui Shan, Er-Wei Zhang, Peng Zhang, Xiao-Dong Zhang, Ning Zhang, Peng Du and Yong Yang

    Citation: BMC Urology 2019 19:115

    Content type: Research article

    Published on:

  4. Chronic inflammation is thought to be a major causative factor for the development of benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS). Tadalafil, a phosphodiesterase type 5 inhibitor...

    Authors: Mikio Sugimoto, Xia Zhang, Nobufumi Ueda, Hiroyuki Tsunemori, Rikiya Taoka, Yusi Hayashida, Hiromi Hirama, Yasuyuki Miyauchi, Yuki Matsuoka, Hirohito Naito, Yu Osaki and Yosiyuki Kekehi

    Citation: BMC Urology 2019 19:99

    Content type: Research article

    Published on:

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