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Urological oncology

This section considers clinical studies relevant to oncological disorders in urology

Page 1 of 6

  1. Hyperglycemia is associated with series of process leading to oncogenesis. Evidence has shown that diabetes mellitus (DM) seems to be associated with poor prognosis in patients with bladder cancer. However, ev...

    Authors: Wei-Lun Huang, Kuo-How Huang, Chao-Yuan Huang, Yeong-Shiau Pu, Hong-Chiang Chang and Po-Ming Chow

    Citation: BMC Urology 2020 20:117

    Content type: Research article

    Published on:

  2. To compare the postoperative continence and clinical outcomes of Retzius-sparing robot-assisted laparoscopic radical prostatectomy (RS-RALP) with non-RS RALP for patients with prostate cancer.

    Authors: Yu-Li Jiang, Gao-Feng Zheng, Ze-Peng Jiang, Zhen-Li, Xie-Lai Zhou, Jin Zhou, Chun-Hua Ye and Kang-Er Wang

    Citation: BMC Urology 2020 20:114

    Content type: Research article

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  3. The neutrophil-lymphocyte ratio (NLR) is a well-known prognostic marker in various cancers. However, its role as a predictive marker for the effectiveness of nivolumab in patients with metastatic RCC (mRCC) re...

    Authors: Naotaka Nishiyama, Megumi hirobe, Takuya Kikushima, Masahiro Matsuki, Atsushi Takahashi, Masahiro Yanase, Keisuke Ichimatsu, Masayuki Egawa, Norihiro Hayashi, Takahito Negishi, Naoya Masumori and Hiroshi Kitamura

    Citation: BMC Urology 2020 20:110

    Content type: Research article

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  4. Stauffer Syndrome (SS) is a paraneoplastic disorder associated with renal cell carcinoma (RCC). First described by Herbert Maurice Stauffer in 1961, it is characterized by hepatic dysfunction in the absence of...

    Authors: Julian Chavarriaga, Nayib Fakih, Juan Cataño, Catalina Villaquiran, Santiago Rodriguez and German Patino

    Citation: BMC Urology 2020 20:105

    Content type: Case report

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  5. To investigate the value of using contrast-enhanced transrectal ultrasound (CETRUS) to reduce unnecessary collection of biopsies during prostate cancer diagnosis and its utility in predicting biochemical recur...

    Authors: Hong-wei Zhao, Jian Li, Jia-Zheng Cao, Juan Lin, Zhu Wang, Jian-yao Lv, Jin-huan Wei, Zhen-hua Chen, Hao-hua Yao, Yi-hui Pan, Zhen-li Gao, Jun-hang Luo, Wei Chen, Lei Shi and Yong Fang

    Citation: BMC Urology 2020 20:100

    Content type: Research article

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  6. Mitomycin (MMC) has been frequently used as the compound for intravesical treatment. The relatively new pyrimidine analog gemcitabine (GEM) has exhibited anticancer effect on various solid cancers, such as the...

    Authors: Rongxin Li, Ye Li, Jun Song, Ke Gao, Kangning Chen, Xiaogang Yang, Yongqiang Ding, Xinlong Ma, Yang Wang, Weipeng Li, Yanan Wang, Zhiping Wang and Zhilong Dong

    Citation: BMC Urology 2020 20:97

    Content type: Research article

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  7. Intravesical bacillus Calmette-Guerin (BCG) therapy is the treatment of choice for patients with T1 or high-grade superficial bladder cancer or those with carcinoma in situ after transurethral resection. A per...

    Authors: Che-Wei Hsu, Yi-Chun Chiu, Hsiao-Yun Hu, Yu-Hua Fan, Shih-Chi Hong and Wei-Ming Cheng

    Citation: BMC Urology 2020 20:91

    Content type: Research article

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  8. Numerous studies show that the pretreatment neutrophil-to-lymphocyte ratio (NLR) is associated with the prognosis of patients with RCC. However, their findings are inconsistent, urging us to explore the progno...

    Authors: Yuan Shao, Bo Wu, Wei Jia, Zikuan Zhang, Qian Chen and Dongwen Wang

    Citation: BMC Urology 2020 20:90

    Content type: Research article

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  9. To evaluate demographic, clinical and pathological characteristics of small renal masses (SRM) (≤ 4 cm) in a Latin-American population provided by LARCG (Latin-American Renal Cancer Group) and analyze predicto...

    Authors: Thiago Camelo Mourão, Diego Abreu, Gustavo F. Carvalhal, Guillermo Gueglio, Walter H. da Costa, Vinicius Fernando Calsavara, Luis Meza-Montoya, Rubén G. Bengió, Carlos Scorticati, Ricardo Castillejos-Molina, Francisco Rodríguez-Covarrubias, Ana María Autran-Gómez, José Gadu Campos-Salcedo, Alejandro Nolazco, Carlos Ameri, Hamilton Zampolli…

    Citation: BMC Urology 2020 20:85

    Content type: Research article

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  10. Several phase 3 studies reported positive results for combinations of Immune-Oncology (IO) and Vascular Endothelial Growth Factor (VEGF) targeted therapies in patients with metastatic clear cell Renal Cell Car...

    Authors: Yasser Ged, Ruby Gupta, Cihan Duzgol, Andrea Knezevic, Natalie Shapnik, Ritesh Kotecha, Martin H. Voss, Darren R. Feldman, Oguz Akin, Sujata Patil, Robert J. Motzer, Brian I. Rini and Chung-Han Lee

    Citation: BMC Urology 2020 20:84

    Content type: Research article

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  11. Partial ablation of the prostate using high-intensity focussed ultrasound (HIFU-PA) is a treatment option for localised prostate cancer. When local recurrence occurs, salvage robot-assisted radical prostatecto...

    Authors: James E. Thompson, Ashwin N. Sridhar, Greg Shaw, Prabhakar Rajan, Anna Mohammed, Timothy P. Briggs, Senthil Nathan, John D. Kelly and Prasanna Sooriakumaran

    Citation: BMC Urology 2020 20:81

    Content type: Research article

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  12. Plasmacytoid urothelial carcinoma (PUC) of the urinary bladder is a variant of urothelial carcinoma that carries a poor prognosis. The epithelial-mesenchymal transition (EMT) has been demonstrated to contribut...

    Authors: Shunichiro Nomura, Yasutomo Suzuki, Jun Akatsuka, Yuki Endo, Akira Shimizu, Tsutomu Hamasaki, Go Kimura and Yukihiro Kondo

    Citation: BMC Urology 2020 20:72

    Content type: Research article

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  13. Androgen deprivation therapy (ADT) is a standard treatment for advanced prostate cancer (PCa). However, PCa recurrence and progression rates during ADT are high. Until now, there has been no evidence regarding...

    Authors: Agus Rizal A. H. Hamid, Harun W. Kusuma Putra, Ningrum Paramita Sari, Putri Diana, Saras Serani Sesari, Eka Novita, Fajar Lamhot Gultom, Meilania Saraswati, Budiana Tanurahardja, Asmarinah, Rainy Umbas and Chaidir A. Mochtar

    Citation: BMC Urology 2020 20:71

    Content type: Research article

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  14. Bladder cancer (BC) treatment can have a detrimental effect on the sexual organs of patients and yet assessment of sexual health needs has been greatly overlooked for these patients compared to those who have ...

    Authors: Agustina Bessa, Rebecca Martin, Christel Häggström, Deborah Enting, Suzanne Amery, Muhammad Shamim Khan, Fidelma Cahill, Harriet Wylie, Samantha Broadhead, Kathryn Chatterton, Sachin Malde, Rajesh Nair, Ramesh Thurairaja, Pardeep Kumar, Anna Haire, Saran Green…

    Citation: BMC Urology 2020 20:64

    Content type: Research article

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  15. Xanthogranulomatous pyelonephritis (XGP) is an uncommon form of chronic pyelonephritis. Most patients of XGP are diffuse in radiology and the clinical features are typical.

    Authors: Xiaobo Ding, Gang Wang, Tiejun Wang, Xiaobo Ma and Yanbo Wang

    Citation: BMC Urology 2020 20:63

    Content type: Case report

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  16. Kidney cancer is a lethal neoplasm that affects several thousands of people every year. Renal cell carcinoma (RCC) is the most common histologic type. Recent developments in the therapeutic approach include an...

    Authors: G. Tsironis, M. Liontos, A. Kyriazoglou, K. Koutsoukos, A. Tsiara, M. Kaparelou, R. Zakopoulou, A. Cohen, E. Skafida, S. Fontara, F. Zagouri, A. Bamias and M. A. Dimopoulos

    Citation: BMC Urology 2020 20:60

    Content type: Research article

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  17. It is well known that androgen-deprivation therapy (ADT) can inevitably drive prostate cancer (PCa) cells into a castration-resistant state. According to the “Warburg effect”, the metabolism of aggressive tumo...

    Authors: Ximing Li, Zhi Chen, Zuan Li, Guihai Huang, Junhao Lin, Qiang Wei, Jianbo Liang and Wei Li

    Citation: BMC Urology 2020 20:61

    Content type: Research article

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  18. Penile squamous cell carcinoma (PSCC) represents an important public health problem for developing countries. The major prognostic factors in PSCC are pathological subtype, perineural invasion, lymphovascular ...

    Authors: Chen Hu, Yu Bai, Jun Li, Guoyin Zhang, Libo Yang, Chengwei Bi, Bin Zhao, Yong Yang, Ruiqian Li, Hongyi Wu, Qilin Wang and Yang Qin

    Citation: BMC Urology 2020 20:57

    Content type: Research article

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  19. A routine blood examination is one of the most rapid, convenient and inexpensive clinical examinations that can reflect a patient’s inflammatory status and other blood conditions, and the prognostic value of r...

    Authors: Jingqi Zhang, Xiaozhou Zhou, Hua Ding, Liwei Wang, Sha Liu, Yuting Liu and Zhiwen Chen

    Citation: BMC Urology 2020 20:31

    Content type: Research article

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  20. Androgen deprivation therapy (ADT) remains a primary treatment for localized prostate cancer (PCa) even though there is no evidence that its use is beneficial in the absence of curative treatment.

    Authors: Heikki Seikkula, Peter J. Boström, Karri Seppä, Janne Pitkäniemi, Nea Malila and Antti Kaipia

    Citation: BMC Urology 2020 20:25

    Content type: Research article

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  21. Sarcomatoid differentiation in renal cell carcinoma (RCC) with vena caval tumour thrombus has been shown to be associated with aggressive behaviours and poor prognosis; however, evidence of the impact of rhabd...

    Authors: Bin Yang, Haizhui Xia, Chuxiao Xu, Min Lu, Shudong Zhang, Guoliang Wang and Lulin Ma

    Citation: BMC Urology 2020 20:14

    Content type: Research article

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  22. Surveilling recurrent urothelial carcinoma (UC) requires frequent cystoscopy, which is invasive, expensive and time-consuming. An accurate urinary biomarker has the potential to reduce the number of cystoscopi...

    Authors: Madhusudan Koya, Sue Osborne, Christophe Chemaslé, Sima Porten, Anne Schuckman and Andrew Kennedy-Smith

    Citation: BMC Urology 2020 20:12

    Content type: Research article

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  23. Post-operative urinary incontinence is a significant concern for patients choosing to undergo a radical prostatectomy (RP) for treatment of prostate cancer. The aim of our study was to determine the effect of ...

    Authors: Diwei Lin, Michael O’Callaghan, Rowan David, Andrew Fuller, Richard Wells, Peter Sutherland and Darren Foreman

    Citation: BMC Urology 2020 20:8

    Content type: Research article

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  24. Preliminary data suggest that the urinary microbiome may play a role in bladder cancer. Information regarding the most suitable method of collecting urine specimens is needed for the large population studies n...

    Authors: Suchitra K. Hourigan, Wei Zhu, Wendy S.W.Wong, Nicole C. Clemency, Marina Provenzano, Thierry Vilboux, John E. Niederhuber, John Deeken, Simon Chung, Kim McDaniel-Wiley and Donald Trump

    Citation: BMC Urology 2020 20:5

    Content type: Research article

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  25. Due to their location away from the nerve bundles, anterior prostate cancers (APC) represent a rational target for image-guided cryoablation. This report describes the feasibility and short-term outcomes of an...

    Authors: Christina Sze, Efrat Tsivian, Kae Jack Tay, Ariel A. Schulman, Leah G. Davis, Rajan T. Gupta and Thomas J. Polascik

    Citation: BMC Urology 2019 19:127

    Content type: Research article

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  26. Bladder hyperthermic intracavitary chemotherapy (HIVEC) has good effectiveness for bladder cancer, but conventional HIVEC systems lack precision and convenient application. To test the safety of a new HIVEC de...

    Authors: Mingchen Ba, Shuzhong Cui, Hui Long, Yuanfeng Gong, Yinbing Wu, Kunpeng Lin, Yinuo Tu, Bahuo Zhang and Wanbo Wu

    Citation: BMC Urology 2019 19:126

    Content type: Research article

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  27. Second-line treatment for urothelial carcinoma (UC) patients is used if progression or failure after platinum-based chemotherapy occurs or if patients are cisplatin-unfit. However, there is still no widely acc...

    Authors: Huitao Wang, Jianhe Liu, Kewei Fang, Changxing Ke, Yongming Jiang, Guang Wang, Tongxin Yang, Tao Chen and Xin Shi

    Citation: BMC Urology 2019 19:125

    Content type: Research article

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  28. Advances in systemic targeted therapies afford treatment opportunities in patients with metastatic renal cell carcinoma (RCC). Elderly patients with metastatic RCC present a subpopulation for consideration owi...

    Authors: Christopher S. Hollenbeak, Eric W. Schaefer, Justin Doan and Jay D. Raman

    Citation: BMC Urology 2019 19:123

    Content type: Research article

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  29. Predictive models that take race into account like the Prostate Cancer Prevention Trial Risk Calculator 2.0 (PCPT RC) and the new Prostate Biopsy Collaborative Group (PBCG) RC have been developed to equitably ...

    Authors: Samuel Carbunaru, Oluwarotimi S. Nettey, Pooja Gogana, Irene B. Helenowski, Borko Jovanovic, Maria Ruden, Courtney M. P. Hollowell, Roohollah Sharifi, Rick A. Kittles, Edward Schaeffer, Peter Gann and Adam B. Murphy

    Citation: BMC Urology 2019 19:121

    Content type: Research article

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  30. Metabolic syndrome (MetS) and serum prostate-specific antigen (PSA) levels are correlated. To investigate the underlying effect of MetS on PSA levels, the relationship between the major pathogenic factors of M...

    Authors: Bo-Wen Xia, Si-Cong Zhao, Zong-Ping Chen, Chao Chen, Tian-Shu Liu, Fan Yang and Yong Yan

    Citation: BMC Urology 2019 19:119

    Content type: Research article

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  31. Bladder cancer is a complex disease associated with high morbidity and mortality. Management of bladder cancer before radical cystectomy continues to be controversial. We compared the long-term efficacy of one...

    Authors: Wasilijiang Wahafu, Sai Liu, Wenbin Xu, Mengtong Wang, Qingbao He, Liming Song, Mingshuai Wang, Feiya Yang, Lin Hua, Yinong Niu and Nianzeng Xing

    Citation: BMC Urology 2019 19:117

    Content type: Research article

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  32. Pelvic floor muscle training (PFM) training for post-prostatectomy incontinence (PPI) is an important rehabilitative approach, but the evidence base is still evolving. We developed a novel PFM training program...

    Authors: Joanne E. Milios, Timothy R. Ackland and Daniel J. Green

    Citation: BMC Urology 2019 19:116

    Content type: Research article

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  33. Retzius-sparing robot-assisted laparoscopic radical prostatectomy (rsRARP) allows entire prostatectomy procedure via the pouch of Douglas. In low- and intermediate-risk prostate cancer (PCa) there is level 1 e...

    Authors: Joanne Nyaboe Nyarangi-Dix, Magdalena Görtz, Georgi Gradinarov, Luisa Hofer, Viktoria Schütz, Claudia Gasch, Jan Philipp Radtke and Markus Hohenfellner

    Citation: BMC Urology 2019 19:113

    Content type: Research article

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  34. To report a new standardized cognitive fusion technique on transperineal targeted biopsy (TB) of prostate, and to evaluate its efficacy for cancer detection combined with systematic biopsy (SB) .

    Authors: Lei Wang, Xiaofei Wang, Wenfeng Zhao, Zichen Zhao, Zhihu Li, Shengmin Fei, He Zhu, Xiang Ji, Bing Yang, Ningchen Li and Yanqun Na

    Citation: BMC Urology 2019 19:107

    Content type: Research article

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  35. Prostate biopsy remains the gold standard approach to verify prostate cancer diagnosis. Transrectal (TR) biopsy is a regular modality, while transperineal (TP) biopsy is an alternative for the patients who dis...

    Authors: Guan-Lin Huang, Chih-Hsiung Kang, Wei-Ching Lee and Po-Hui Chiang

    Citation: BMC Urology 2019 19:101

    Content type: Research article

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  36. Robotic stereotactic ablative radiotherapy (SABR) is currently under investigation as a noninvasive treatment option for patients with renal cell carcinoma (RCC). For radiation therapy of RCC, tumor motion and...

    Authors: C. Senger, A. Conti, A. Kluge, D. Pasemann, M. Kufeld, G. Acker, M. Lukas, A. Grün, G. Kalinauskaite, V. Budach, J. Waiser and C. Stromberger

    Citation: BMC Urology 2019 19:96

    Content type: Research article

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  37. Accurate grading at the time of diagnosis if fundamental to risk stratification and treatment decision making in patients with prostate cancer. Whilst previous studies have demonstrated significant pathologica...

    Authors: Nicholas Bullock, Andrew Simpkin, Sarah Fowler, Murali Varma, Howard Kynaston and Krishna Narahari

    Citation: BMC Urology 2019 19:94

    Content type: Research article

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  38. Fatigue is one of the most prevalent symptoms among cancer patients. Specifically, in metastatic castration-resistant prostate cancer (mCRPC) patients, fatigue is the most common adverse event associated with ...

    Authors: A. Rodríguez Antolín, L. Martínez-Piñeiro, M. E. Jiménez Romero, J. B. García Ramos, D. López Bellido, J. Muñoz del Toro, A. García García-Porrero and F. Gómez Veiga

    Citation: BMC Urology 2019 19:92

    Content type: Research article

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  39. Because of the failure, shortage and related toxicities of Bacillus Calmette-Guérin (BCG), the other intravesical chemotherapy drugs are also widely used in clinical application. Gemcitabine and anthracycline ...

    Authors: Tian-Wei Wang, Hui Yuan, Wen-Li Diao, Rong Yang, Xiao-Zhi Zhao and Hong-Qian Guo

    Citation: BMC Urology 2019 19:90

    Content type: Research article

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  40. A variety of penile rehabilitation (PR) therapies are available to improve post-prostatectomy erectile dysfunction (ED) with mixed results. It is uncertain how adherent men are to PR therapies. The aim of this...

    Authors: Jeffrey Albaugh, Brittany Adamic, Cecilia Chang, Nicholas Kirwen and Joshua Aizen

    Citation: BMC Urology 2019 19:89

    Content type: Research article

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  41. We investigated the impact of postoperative membranous urethral length and other anatomic characteristics of the pelvic floor shape as measured by magnetic resonance imaging on the improvement in continence fo...

    Authors: Akihiro Nakane, Hiroki Kubota, Yusuke Noda, Tomoki Takeda, Yasuhiko Hirose, Atsushi Okada, Kentaro Mizuno, Noriyasu Kawai, Keiichi Tozawa, Yutaro Hayashi and Takahiro Yasui

    Citation: BMC Urology 2019 19:87

    Content type: Research article

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  42. There is an increased incidence of renal cell carcinoma (RCC) in patients with metabolic syndrome who usually have high levels of serum triglyceride (TG) and low high-density lipoprotein-cholesterol (HDL-C). P...

    Authors: Emre Karabay, Nejdet Karsiyakali, Serdar Duvar, Cagatay Tosun, Ahmet Ruknettin Aslan and Omer Ergin Yucebas

    Citation: BMC Urology 2019 19:85

    Content type: Research article

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  43. In patients presenting with limited nodal recurrence following radical prostatectomy (RP), stereotactic body radiotherapy (SBRT) results might improve with a better case selection.

    Authors: Christoph Oehler, Michel Zimmermann, Lukas Adam, Juergen Curschmann, Marcin Sumila, Räto T. Strebel, Richard Cathomas, Qiyu Li, Uwe Schneider and Daniel R. Zwahlen

    Citation: BMC Urology 2019 19:84

    Content type: Research article

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  44. Perivesical lymph nodes (PVLNs) are occasionally isolated during grossing of cystectomy specimens. However, the prognostic implications of the involvement of PVLNs in bladder cancer patients, especially those ...

    Authors: Meenal Sharma, Takuro Goto, Zhiming Yang and Hiroshi Miyamoto

    Citation: BMC Urology 2019 19:77

    Content type: Research article

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  45. Strong evidence comparing effectiveness between nephron-sparing intervention (NSI) and active surveillance (AS) is lacking. Thus, we aim to compare the outcomes of survival, including cancer-specific survival ...

    Authors: Run-Qi Guo and Xiao-Guang Li

    Citation: BMC Urology 2019 19:74

    Content type: Research article

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  46. Patient-related factors such as concern about cancer are believed to influence both men’s decisions to undergo prostate specific antigen (PSA) testing and to have definitive treatment if diagnosed with low ris...

    Authors: Kerri Beckmann, Netty Kinsella, Henrik Olsson, Anna Wallerstedt Lantz, Tobias Nordstrom, Markus Aly, Jan Adolfsson, Martin Eklund and Mieke Van Hemelrijck

    Citation: BMC Urology 2019 19:73

    Content type: Research article

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  47. Due to the usage of various measurement methods and definitions, comparing continence rates after radical prostatectomy is a challenging task. This study compares continence rates based on different methods an...

    Authors: Sigrun Holze, Meinhard Mende, Karl V. Healy, Norbert Koehler, Lutz Gansera, Michael C. Truss, Udo Rebmann, Stephan Degener and Jens-Uwe Stolzenburg

    Citation: BMC Urology 2019 19:70

    Content type: Research article

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  • BMC Urology works with with Cochrane Urology in providing our authors with expert advice on systematic reviews and meta-analyses

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