Urological oncology

Section edited by Philippe Spiess, Jose Karam and Chris Protzel

This section considers clinical studies relevant to oncological disorders in urology

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  1. Research article

    Assessment of lower urinary symptom flare with overactive bladder symptom score and International Prostate Symptom Score in patients treated with iodine-125 implant brachytherapy: long-term follow-up experience at a single institute

    The aim of this study was to evaluate the combined use of the overactive bladder symptom score (OABSS) and International Prostate Symptom Score (IPSS) as an assessment tool for urinary symptom flare after iodi...

    Makito Miyake, Nobumichi Tanaka, Isao Asakawa, Shunta Hori, Yosuke Morizawa, Yoshihiro Tatsumi, Yasushi Nakai, Takeshi Inoue, Satoshi Anai, Kazumasa Torimoto, Katsuya Aoki, Masatoshi Hasegawa, Tomomi Fujii, Noboru Konishi and Kiyohide Fujimoto

    BMC Urology 2017 17:62

    Published on: 14 August 2017

  2. Research article

    Heterogeneity in high-risk prostate cancer treated with high-dose radiation therapy and androgen deprivation therapy

    Our aim was to assess the heterogeneity of high-risk (HR) prostate cancer managed with high-dose external beam radiotherapy (EBRT) with androgen deprivation therapy (ADT).

    Daniel N. Cagney, Mary Dunne, Carmel O’Shea, Marie Finn, Emma Noone, Martina Sheehan, Lesley McDonagh, Lydia O’Sullivan, Pierre Thirion and John Armstrong

    BMC Urology 2017 17:60

    Published on: 1 August 2017

  3. Research article

    Assessment of free-hand transperineal targeted prostate biopsy using multiparametric magnetic resonance imaging-transrectal ultrasound fusion in Chinese men with prior negative biopsy and elevated prostate-specific antigen

    To evaluate the role of free-hand transperineal targeted prostate biopsy using multiparametric magnetic resonance imaging-transrectal ultrasound (mpMRI-TRUS) fusion in Chinese men with repeated biopsy.

    Huibo Lian, Junlong Zhuang, Wei Wang, Bing Zhang, Jiong Shi, Danyan Li, Yao Fu, Xuping Jiang, Weimin Zhou and Hongqian Guo

    BMC Urology 2017 17:52

    Published on: 5 July 2017

  4. Research article

    The neutrophil-to-lymphocyte ratio (NLR) predicts adrenocortical carcinoma and is correlated with the prognosis

    The neutrophil-to-lymphocyte ratio (NLR) is reported as a biomarker for some solid malignant diseases. Thus far, however, no reports of the relationship between the NLR and adrenal tumors have been published. ...

    Taku Mochizuki, Takashi Kawahara, Daiji Takamoto, Kazuhide Makiyama, Yusuke Hattori, Jun-ichi Teranishi, Yasuhide Miyoshi, Yasushi Yumura, Masahiro Yao and Hiroji Uemura

    BMC Urology 2017 17:49

    Published on: 29 June 2017

  5. Research article

    Performance characteristics of prostate-specific antigen density and biopsy core details to predict oncological outcome in patients with intermediate to high-risk prostate cancer underwent robot-assisted radical prostatectomy

    Many urologic surgeons refer to biopsy core details for decision making in cases of localized prostate cancer (PCa) to determine whether an extended resection and/or lymph node dissection should be performed. ...

    Masahiro Yashi, Akinori Nukui, Yuumi Tokura, Kohei Takei, Issei Suzuki, Kazumasa Sakamoto, Hideo Yuki, Tsunehito Kambara, Hironori Betsunoh, Hideyuki Abe, Yoshitatsu Fukabori, Yoshimasa Nakazato, Yasushi Kaji and Takao Kamai

    BMC Urology 2017 17:47

    Published on: 23 June 2017

  6. Case report

    A rare presentation of metastatic prostate cancer, initially a suspect for urothelial cell carcinoma of the ureter: a case report

    The most common metastatic sites of prostate cancer are the lymph nodes and bone. Ureteral metastasis from prostate cancer is very unusual and only a few cases have been reported.

    Ho Seok Chung, Myung Soo Kim, Yang Hyun Cho, Eu Chang Hwang, Seung Il Jung, Taek Won Kang, Dong Deuk Kwon, Suk Hee Heo and Chan Choi

    BMC Urology 2017 17:37

    Published on: 26 May 2017

  7. Research article

    Qualitative insights into how men with low-risk prostate cancer choosing active surveillance negotiate stress and uncertainty

    Active surveillance is a management strategy for men diagnosed with early-stage, low-risk prostate cancer in which their cancer is monitored and treatment is delayed. This study investigated the primary coping...

    Emily M. Mader, Hsin H. Li, Kathleen D. Lyons, Christopher P. Morley, Margaret K. Formica, Scott D. Perrapato, Brian H. Irwin, John D. Seigne, Elias S. Hyams, Terry Mosher, Mark T. Hegel and Telisa M. Stewart

    BMC Urology 2017 17:35

    Published on: 8 May 2017

  8. Research article

    Lymphoepithelioma-like, a variant of urothelial carcinoma of the urinary bladder: a case report and systematic review for optimal treatment modality for disease-free survival

    Lymphoepithelioma-like carcinoma (LELC) is a rare high-grade carcinoma that resembles nasopharyngeal lymphoepithelioma and can occur throughout the body. First reported in 1991, bladder LELC has an incidence o...

    Andy W. Yang, Aydin Pooli, Subodh M. Lele, Ina W. Kim, Judson D. Davies and Chad A. LaGrange

    BMC Urology 2017 17:34

    Published on: 27 April 2017

  9. Research article

    Transperineal template-guided saturation biopsy aimed at sampling one core for each milliliter of prostate volume: 103 cases requiring repeat prostate biopsy

    We evaluated the cancer detection rate of prostate cancer using transperineal template-guided saturation biopsy aimed at sampling one core for each milliliter of prostate volume for patients requiring repeated...

    Yasushi Nakai, Nobumichi Tanaka, Satoshi Anai, Makito Miyake, Shunta Hori, Yoshihiro Tatsumi, Yosuke Morizawa, Tomomi Fujii, Noboru Konishi and Kiyohide Fujimoto

    BMC Urology 2017 17:28

    Published on: 5 April 2017

  10. Research article

    BAP1 and PBRM1 in metastatic clear cell renal cell carcinoma: tumor heterogeneity and concordance with paired primary tumor

    BAP1 and PBRM1 are frequently mutated in primary clear cell renal cell carcinoma (ccRCC) tumors; however, the frequency and clinical relevance of these mutations in metastatic ccRCC tumors is unknown. Addition...

    Jeanette E. Eckel-Passow, Daniel J. Serie, John C. Cheville, Thai H. Ho, Payal Kapur, James Brugarolas, R. Houston Thompson, Bradley C. Leibovich, Eugene D. Kwon, Richard W. Joseph and Alexander S. Parker

    BMC Urology 2017 17:19

    Published on: 21 March 2017

  11. Review

    miRNAs associated with prostate cancer risk and progression

    Prostate cancer is the most common malignancy among men in the US. Though considerable improvement in the diagnosis of prostate cancer has been achieved in the past decade, predicting disease outcome remains a...

    Hung N. Luu, Hui-Yi Lin, Karina Dalsgaard Sørensen, Olorunseun O. Ogunwobi, Nagi Kumar, Ganna Chornokur, Catherine Phelan, Dominique Jones, LaCreis Kidd, Jyotsna Batra, Kosj Yamoah, Anders Berglund, Robert J. Rounbehler, Mihi Yang, Sang Haak Lee, Nahyeon Kang…

    BMC Urology 2017 17:18

    Published on: 20 March 2017

  12. Research article

    Aortic calcification burden predicts deterioration of renal function after radical nephrectomy

    Radical nephrectomy for renal cell carcinoma (RCC) is a risk factor for the development of chronic kidney disease (CKD), and the possibility of postoperative deterioration of renal function must be considered ...

    Ken Fukushi, Shingo Hatakeyama, Hayato Yamamoto, Yuki Tobisawa, Tohru Yoneyama, Osamu Soma, Teppei Matsumoto, Itsuto Hamano, Takuma Narita, Atsushi Imai, Takahiro Yoneyama, Yasuhiro Hashimoto, Takuya Koie, Yuriko Terayama, Tomihisa Funyu and Chikara Ohyama

    BMC Urology 2017 17:13

    Published on: 6 February 2017

  13. Research article

    Genetic polymorphisms in key hypoxia-regulated downstream molecules and phenotypic correlation in prostate cancer

    In this study we sought if, in their quest to handle hypoxia, prostate tumors express target hypoxia-associated molecules and their correlation with putative functional genetic polymorphisms.

    Avelino Fraga, Ricardo Ribeiro, André Coelho, José Ramon Vizcaíno, Helena Coutinho, José Manuel Lopes, Paulo Príncipe, Carlos Lobato, Carlos Lopes and Rui Medeiros

    BMC Urology 2017 17:12

    Published on: 31 January 2017

  14. Research article

    Do men regret prostate biopsy: Results from the PiCTure study

    Understanding men’s experience of prostate biopsy is important as the procedure is common, invasive and carries potential risks. The psychological aspects of prostate biopsy have been somewhat neglected. The a...

    Catherine Coyle, Eileen Morgan, Frances J. Drummond, Linda Sharp and Anna Gavin

    BMC Urology 2017 17:11

    Published on: 26 January 2017

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