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Urological oncology

This section considers clinical studies relevant to oncological disorders in urology

Page 2 of 4

  1. Content type: Case report

    The most common metastatic sites of prostate cancer are the lymph nodes and bone. Ureteral metastasis from prostate cancer is very unusual and only a few cases have been reported.

    Authors: Ho Seok Chung, Myung Soo Kim, Yang Hyun Cho, Eu Chang Hwang, Seung Il Jung, Taek Won Kang, Dong Deuk Kwon, Suk Hee Heo and Chan Choi

    Citation: BMC Urology 2017 17:37

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  2. Content type: Research article

    Active surveillance is a management strategy for men diagnosed with early-stage, low-risk prostate cancer in which their cancer is monitored and treatment is delayed. This study investigated the primary coping...

    Authors: Emily M. Mader, Hsin H. Li, Kathleen D. Lyons, Christopher P. Morley, Margaret K. Formica, Scott D. Perrapato, Brian H. Irwin, John D. Seigne, Elias S. Hyams, Terry Mosher, Mark T. Hegel and Telisa M. Stewart

    Citation: BMC Urology 2017 17:35

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  3. Content type: Research article

    Lymphoepithelioma-like carcinoma (LELC) is a rare high-grade carcinoma that resembles nasopharyngeal lymphoepithelioma and can occur throughout the body. First reported in 1991, bladder LELC has an incidence o...

    Authors: Andy W. Yang, Aydin Pooli, Subodh M. Lele, Ina W. Kim, Judson D. Davies and Chad A. LaGrange

    Citation: BMC Urology 2017 17:34

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  4. Content type: Research article

    We evaluated the cancer detection rate of prostate cancer using transperineal template-guided saturation biopsy aimed at sampling one core for each milliliter of prostate volume for patients requiring repeated...

    Authors: Yasushi Nakai, Nobumichi Tanaka, Satoshi Anai, Makito Miyake, Shunta Hori, Yoshihiro Tatsumi, Yosuke Morizawa, Tomomi Fujii, Noboru Konishi and Kiyohide Fujimoto

    Citation: BMC Urology 2017 17:28

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  5. Content type: Research article

    BAP1 and PBRM1 are frequently mutated in primary clear cell renal cell carcinoma (ccRCC) tumors; however, the frequency and clinical relevance of these mutations in metastatic ccRCC tumors is unknown. Addition...

    Authors: Jeanette E. Eckel-Passow, Daniel J. Serie, John C. Cheville, Thai H. Ho, Payal Kapur, James Brugarolas, R. Houston Thompson, Bradley C. Leibovich, Eugene D. Kwon, Richard W. Joseph and Alexander S. Parker

    Citation: BMC Urology 2017 17:19

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  6. Content type: Review

    Prostate cancer is the most common malignancy among men in the US. Though considerable improvement in the diagnosis of prostate cancer has been achieved in the past decade, predicting disease outcome remains a...

    Authors: Hung N. Luu, Hui-Yi Lin, Karina Dalsgaard Sørensen, Olorunseun O. Ogunwobi, Nagi Kumar, Ganna Chornokur, Catherine Phelan, Dominique Jones, LaCreis Kidd, Jyotsna Batra, Kosj Yamoah, Anders Berglund, Robert J. Rounbehler, Mihi Yang, Sang Haak Lee, Nahyeon Kang…

    Citation: BMC Urology 2017 17:18

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  7. Content type: Research article

    Radical nephrectomy for renal cell carcinoma (RCC) is a risk factor for the development of chronic kidney disease (CKD), and the possibility of postoperative deterioration of renal function must be considered ...

    Authors: Ken Fukushi, Shingo Hatakeyama, Hayato Yamamoto, Yuki Tobisawa, Tohru Yoneyama, Osamu Soma, Teppei Matsumoto, Itsuto Hamano, Takuma Narita, Atsushi Imai, Takahiro Yoneyama, Yasuhiro Hashimoto, Takuya Koie, Yuriko Terayama, Tomihisa Funyu and Chikara Ohyama

    Citation: BMC Urology 2017 17:13

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  8. Content type: Research article

    In this study we sought if, in their quest to handle hypoxia, prostate tumors express target hypoxia-associated molecules and their correlation with putative functional genetic polymorphisms.

    Authors: Avelino Fraga, Ricardo Ribeiro, André Coelho, José Ramon Vizcaíno, Helena Coutinho, José Manuel Lopes, Paulo Príncipe, Carlos Lobato, Carlos Lopes and Rui Medeiros

    Citation: BMC Urology 2017 17:12

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  9. Content type: Research article

    Understanding men’s experience of prostate biopsy is important as the procedure is common, invasive and carries potential risks. The psychological aspects of prostate biopsy have been somewhat neglected. The a...

    Authors: Catherine Coyle, Eileen Morgan, Frances J. Drummond, Linda Sharp and Anna Gavin

    Citation: BMC Urology 2017 17:11

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  10. Content type: Research article

    Partial nephrectomy for small renal masses (SRM) may be useful for preserving renal function, but is technically more difficult than radical nephrectomy. Cryoablation may be performed under local anesthesia. T...

    Authors: Fumiya Hongo, Yasuhiro Yamada, Takashi Ueda, Terukazu Nakmura, Yoshio Naya, Kazumi Kamoi, Koji Okihara, Yusuke Ichijo, Tsuneharu Miki, Kei Yamada and Osamu Ukimura

    Citation: BMC Urology 2017 17:10

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  11. Content type: Research article

    The goal was to assess the natural history and management of patients with pathologically proven bilateral (synchronous) RO after undergoing initial partial nephrectomy (PN).

    Authors: Andrew R. Leone, Laura C. Kidd, Gregory J. Diorio, Kamran Zargar-Shoshtari, Pranav Sharma, Wade J. Sexton and Philippe E. Spiess

    Citation: BMC Urology 2017 17:6

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  12. Content type: Research article

    Immunotherapy with high-dose interleukin-2 (HD-IL2) results in long-term survival in some metastatic renal cell carcinoma (mRCC) patients but has significant acute toxicities. Biomarkers predicting response to...

    Authors: James A. Kuzman, David D. Stenehjem, Joseph Merriman, Archana M. Agarwal, Shiven B. Patel, Andrew W. Hahn, Anitha Alex, Dan Albertson, David M. Gill and Neeraj Agarwal

    Citation: BMC Urology 2017 17:1

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  13. Content type: Research article

    Up to a fifth of patients diagnosed with prostate cancer (PC) will develop castration-resistant prostate cancer (CRPC), which has been associated with a poor prognosis. The aim of this study was to consider th...

    Authors: Hiroji Uemura, Nobuaki Matsubara, Go Kimura, Akito Yamaguchi, Dianne Athene Ledesma, Marco DiBonaventura, Ateesha F. Mohamed, Enrique Basurto, Ian McKinnon, Ed Wang, Kristen Concialdi, Aya Narimatsu and Yasuko Aitoku

    Citation: BMC Urology 2016 16:63

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    The Erratum to this article has been published in BMC Urology 2017 17:20

  14. Content type: Research article

    The aim was to evaluate cancer-specific survival (CSS) and overall survival (OS) in patients with prostate cancer (PCa) recurrence who underwent salvage extended pelvic lymph node dissection (ePLND), taking in...

    Authors: Daniar K. Osmonov, Alexey V. Aksenov, David Trick, Carsten M. Naumann, Moritz F. Hamann, Amr Abou Faddan and Klaus-Peter Jünemann

    Citation: BMC Urology 2016 16:56

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  15. Content type: Research article

    Methylation of the tumor suppressor gene H-cadherin (CDH13) has been reported in many cancers. However, the clinical effect of the CDH13 methylation status of patients with bladder cancer remains to be clarified.

    Authors: Feng Chen, Tao Huang, Yu Ren, Junjun Wei, Zhongguan Lou, Xue Wang, Xiaoxiao Fan, Yirun Chen, Guobin Weng and Xuping Yao

    Citation: BMC Urology 2016 16:52

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  16. Content type: Research article

    The guidelines of the European Association of Urologists (EAU), of the German Society of Nuclear Medicine (DGN), and the European Society for Medical Oncology (ESMO) recommend sentinel lymph node biopsy (SLNB)...

    Authors: Ulf Lützen, Carsten Maik Naumann, Jens Dischinger, Marlies Marx, René Baumann, Yi Zhao, Michael Jüptner, Daniar Osmonov, Katrin Bothe, Klaus-Peter Jünemann and Maaz Zuhayra

    Citation: BMC Urology 2016 16:47

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  17. Content type: Research article

    Androgen deprivation therapy (ADT) is an effective palliation treatment in men with advanced prostate cancer (PC). However, ADT has well documented side effects that could alter the patient’s health-related qu...

    Authors: Nishi Karunasinghe, Yifei Zhu, Dug Yeo Han, Katja Lange, Shuotun Zhu, Alice Wang, Stephanie Ellett, Jonathan Masters, Megan Goudie, Justin Keogh, Benji Benjamin, Michael Holmes and Lynnette R. Ferguson

    Citation: BMC Urology 2016 16:48

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  18. Content type: Research article

    The efficacy and/or tolerability of pazopanib in patients with metastatic renal cell carcinoma (mRCC) have been found to differ in Western and Asian populations. This retrospective multicenter study analyzed t...

    Authors: Moon Jin Kim, Se Hoon Park, Jae-Lyun Lee, Se-Hoon Lee, Su Jin Lee and Ho Yeong Lim

    Citation: BMC Urology 2016 16:46

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  19. Content type: Research article

    The management of patients with renal cell carcinoma (RCC) with venous tumor thrombus (VTT) is challenging. We report our 15 year experience in the management of patients with RCC with VTT utilizing a multidis...

    Authors: Bishoy A. Gayed, Ramy Youssef, Oussama Darwish, Payal Kapur, Aditya Bagrodia, James Brugarolas, Ganesh Raj, J. Michael DiMaio, Arthur Sagalowsky and Vitaly Margulis

    Citation: BMC Urology 2016 16:43

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  20. Content type: Research article

    To validate the association between obesity and penile cancer at a population level, we conducted a matched case–control study linking the Iowa Department of Motor Vehicles Drivers’ License Database (DLD) with...

    Authors: Kerri T. Barnes, Bradley D. McDowell, Anna Button, Brian J. Smith, Charles F. Lynch and Amit Gupta

    Citation: BMC Urology 2016 16:42

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  21. Content type: Research article

    Renal cell carcinoma (RCC) associated with Xp11.2 translocation/TFE3 gene fusion (Xp11.2 RCC) is a rare subtype of RCC which is firstly described as a distinct entity in 2004 so that clinical characteristics o...

    Authors: Xiangming Cheng, Weidong Gan, Gutian Zhang, Xiaogong Li and Hongqian Guo

    Citation: BMC Urology 2016 16:40

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  22. Content type: Research article

    The standard of care in patients with suspected prostate cancer (PCa) is systematic prostate biopsies. This approach leads to unnecessary biopsies in patients without PCa and also to the detection of clinical ...

    Authors: Yngve Nygård, Svein A. Haukaas, Ole J. Halvorsen, Karsten Gravdal, Jannicke Frugård, Lars A. Akslen and Christian Beisland

    Citation: BMC Urology 2016 16:39

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  23. Content type: Research article

    The currently recommended treatment algorithm for patients with advanced renal cell carcinoma who fail the first-line targeted therapy does not normally include pazopanib as a second-line treatment option. It ...

    Authors: Victor C. Kok and Jung-Tsung Kuo

    Citation: BMC Urology 2016 16:34

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  24. Content type: Research article

    Spectrum effects refer to the phenomenon that test performance varies across subgroups of a population. When spectrum effects occur during diagnostic testing for cancer, difficult patient misdiagnoses can occu...

    Authors: Ajay Gopalakrishna, Thomas A. Longo, Joseph J. Fantony, Richmond Owusu, Wen-Chi Foo, Rajesh Dash and Brant A. Inman

    Citation: BMC Urology 2016 16:30

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  25. Content type: Research article

    We propose to improve the prognostic assessment after radical prostatectomy (RP) by dividing high-risk prostate cancer (hrPCa) (according to the d’Amico classification) into subgroups combining 1, 2 or 3 crite...

    Authors: Jean-Baptiste Beauval, Mathieu Roumiguié, Thomas Filleron, Thibaut Benoit, Alexandre de la Taille, Bernard Malavaud, Laurent Salomon, Michel Soulié and Guillaume Ploussard

    Citation: BMC Urology 2016 16:26

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  26. Content type: Research article

    Previous studies have demonstrated an association between prostate-specific antigen (PSA) kinetics and predictive value for treatment outcomes. Abiraterone acetate (AA) is a newly approved cytochrome-P450C17 i...

    Authors: Masahiko Nakayama, Hisanori Kobayashi, Tomihiro Takahara, Ryo Oyama, Keiichiro Imanaka and Kazutake Yoshizawa

    Citation: BMC Urology 2016 16:27

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  27. Content type: Research article

    Intestinal metaplasia of the bladder is an uncommon glandular proliferation. We examined a large series of intestinal metaplasia for the clinicopathological features and discuss the significance of this lesion.

    Authors: Zhixiang Xin, Chenhui Zhao, Tao Huang, Zhaohui Zhang, Chenlong Chu, Caifeng Lu, Min Wu and Wenlong Zhou

    Citation: BMC Urology 2016 16:24

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  28. Content type: Research article

    [−2]proPSA and its derivatives have an higher diagnostic accuracy than PSA in predicting prostate cancer (PCa). In alternative to PSA, ultrasensitive PSA (uPSA) and [−2]proPSA could be potentially useful in re...

    Authors: S. De Luca, R. Passera, A. Sottile, C. Fiori, R. M. Scarpa and F. Porpiglia

    Citation: BMC Urology 2016 16:14

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  29. Content type: Research article

    A possible role for prostate cancer in Lynch syndrome has been debated based on observations of mismatch-repair defective tumors and reports of an increased risk of prostate cancer in mutation carriers. Potent...

    Authors: Mev Dominguez-Valentin, Patrick Joost, Christina Therkildsen, Mats Jonsson, Eva Rambech and Mef Nilbert

    Citation: BMC Urology 2016 16:15

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  30. Content type: Research article

    There is much interest in confirming whether the efficacy of abiraterone acetate (AA) demonstrated within the trial setting is reproducible in routine clinical practice. We report the clinical outcome of metas...

    Authors: Darren M. C. Poon, Kuen Chan, S. H. Lee, T. W. Chan, Henry Sze, Eric K. C. Lee, Daisy Lam and Michelle F. T. Chan

    Citation: BMC Urology 2016 16:12

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  31. Content type: Research article

    While novel drugs have been developed, docetaxel remains one of the standard initial systemic therapies for castration-resistant prostate cancer (CRPC) patients. Despite the excellent anti-tumor effect of doce...

    Authors: Shimpei Yamashita, Yasuo Kohjimoto, Takashi Iguchi, Hiroyuki Koike, Hiroki Kusumoto, Akinori Iba, Kazuro Kikkawa, Yoshiki Kodama, Nagahide Matsumura and Isao Hara

    Citation: BMC Urology 2016 16:13

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  32. Content type: Research article

    The high false negative rates for initial prostate biopsies refer a large number of the men for repeat biopsies each year. Therefore, biomarkers associated with high risk of the presence of malignancy in histo...

    Authors: Saeid Alinezhad, Riina-Minna Väänänen, Natalia Tong Ochoa, Emily A. Vertosick, Anders Bjartell, Peter J Boström, Pekka Taimen and Kim Pettersson

    Citation: BMC Urology 2016 16:10

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  33. Content type: Research article

    Lymphovascular invasion (LVI) is an important step in the process of tumor dissemination and metastasis outside the primary organ, but the relationship between LVI and the prognosis of T1 non-muscle invasive b...

    Authors: Keishiro Fukumoto, Eiji Kikuchi, Shuji Mikami, Akira Miyajima and Mototsugu Oya

    Citation: BMC Urology 2016 16:5

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  34. Content type: Research article

    Measurement of the prostate specific antigen (PSA) remains an important tool in prostate cancer (PC) diagnosis. Due to limited availability of laboratory devices in an outpatient setting, compact and easy-to-h...

    Authors: Steffen Rausch, Joerg Hennenlotter, Josef Wiesenreiter, Andrea Hohneder, Julian Heinkele, Christian Schwentner, Arnulf Stenzl and Tilman Todenhöfer

    Citation: BMC Urology 2016 16:4

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  35. Content type: Research article

    Current therapies for advanced renal cell carcinoma (RCC) have low cure rates or significant side effects. It has been reported that complexes composed of interleukin (IL)-2 and stimulating anti-IL-2 antibody ...

    Authors: Kyu-Hyun Han, Ki Won Kim, Ji-Jing Yan, Jae-Ghi Lee, Eun Mi Lee, Miyeon Han, Eun Jin Cho, Seong Sik Kang, Hye Jin Lim, Tai Yeon Koo, Curie Ahn and Jaeseok Yang

    Citation: BMC Urology 2016 16:2

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  36. Content type: Research article

    The American Urological Association (AUA) changed their Prostate-Specific Antigen (PSA) screening guidelines in 2013 to not recommend testing in men under 55 years of age without significant risk factors (such...

    Authors: Nandu D. Dantanarayana, Tania Hossack, Paul Cozzi, Andrew Brooks, Howard Lau, Warick Delprado and Manish I. Patel

    Citation: BMC Urology 2015 15:124

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  37. Content type: Research article

    Prostate cancer is the second most common diagnosed cancer in men. Due to the low specificity of current diagnosis methods for detecting prostate cancer, identification of new biomarkers is highly desirable. T...

    Authors: Jin Huang, Kathleen H. Reilly, Hui-Zhen Zhang and Hai-Bo Wang

    Citation: BMC Urology 2015 15:118

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  38. Content type: Research article

    Prostate cancer remains the most common cancer in men. Qualitative or semi-quantitative immunochromatographic measurements of prostate specific antigen (PSA) have been shown to be simple, noninvasive and feasi...

    Authors: Cheng-Ching Wu, Hung-Yu Lin, Chao-Ping Wang, Li-Fen Lu, Teng-Hung Yu, Wei-Chin Hung, Jer-Yiing Houng, Fu-Mei Chung, Yau-Jiunn Lee and Jin-Jia Hu

    Citation: BMC Urology 2015 15:109

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  39. Content type: Research article

    To investigate the efficacy of initial biopsy or transurethral resection of bladder tumor for detecting histological variants on radical cystectomy and to assess the prognostic significance of variant histolog...

    Authors: Peng Ge, Zi-Cheng Wang, Xi Yu, Jian Lin and Qun He

    Citation: BMC Urology 2015 15:46

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  40. Content type: Research article

    Urothelial carcinoma (UC) is a common cancer affecting many patients in the United States. Nephroureterectomy remains the gold standard for the treatment of high grade upper tract disease or low grade tumors t...

    Authors: Michael A. Moriarty, Matthew A. Uhlman, Megan T. Bing, Michael A. O’Donnell, James A. Brown, Chad R. Tracy, Sundeep Deorah, Kenneth G. Nepple and Amit Gupta

    Citation: BMC Urology 2015 15:45

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  41. Content type: Research article

    Adrenocortical carcinoma (ACC) is aggressive, but rare tumours that have not been sufficiently studied. The aim of our study was to present the demographic and clinical characteristics of patients with ACC, to...

    Authors: Zlatibor Loncar, Vladimir Djukic, Vladan Zivaljevic, Tatjana Pekmezovic, Aleksandar Diklic, Svetislav Tatic, Dusko Dundjerovic, Branislav Olujic, Nikola Slijepcevic and Ivan Paunovic

    Citation: BMC Urology 2015 15:43

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