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BMC Urology

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Urological oncology

Section edited by Philippe Spiess, Jose Karam and Chris Protzel

This section considers clinical studies relevant to oncological disorders in urology

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  1. Content type: Research article

    The aim was to evaluate cancer-specific survival (CSS) and overall survival (OS) in patients with prostate cancer (PCa) recurrence who underwent salvage extended pelvic lymph node dissection (ePLND), taking in...

    Authors: Daniar K. Osmonov, Alexey V. Aksenov, David Trick, Carsten M. Naumann, Moritz F. Hamann, Amr Abou Faddan and Klaus-Peter Jünemann

    Citation: BMC Urology 2016 16:56

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  2. Content type: Research article

    Methylation of the tumor suppressor gene H-cadherin (CDH13) has been reported in many cancers. However, the clinical effect of the CDH13 methylation status of patients with bladder cancer remains to be clarified.

    Authors: Feng Chen, Tao Huang, Yu Ren, Junjun Wei, Zhongguan Lou, Xue Wang, Xiaoxiao Fan, Yirun Chen, Guobin Weng and Xuping Yao

    Citation: BMC Urology 2016 16:52

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  3. Content type: Research article

    The guidelines of the European Association of Urologists (EAU), of the German Society of Nuclear Medicine (DGN), and the European Society for Medical Oncology (ESMO) recommend sentinel lymph node biopsy (SLNB)...

    Authors: Ulf Lützen, Carsten Maik Naumann, Jens Dischinger, Marlies Marx, René Baumann, Yi Zhao, Michael Jüptner, Daniar Osmonov, Katrin Bothe, Klaus-Peter Jünemann and Maaz Zuhayra

    Citation: BMC Urology 2016 16:47

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  4. Content type: Research article

    Androgen deprivation therapy (ADT) is an effective palliation treatment in men with advanced prostate cancer (PC). However, ADT has well documented side effects that could alter the patient’s health-related qu...

    Authors: Nishi Karunasinghe, Yifei Zhu, Dug Yeo Han, Katja Lange, Shuotun Zhu, Alice Wang, Stephanie Ellett, Jonathan Masters, Megan Goudie, Justin Keogh, Benji Benjamin, Michael Holmes and Lynnette R. Ferguson

    Citation: BMC Urology 2016 16:48

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  5. Content type: Research article

    The efficacy and/or tolerability of pazopanib in patients with metastatic renal cell carcinoma (mRCC) have been found to differ in Western and Asian populations. This retrospective multicenter study analyzed t...

    Authors: Moon Jin Kim, Se Hoon Park, Jae-Lyun Lee, Se-Hoon Lee, Su Jin Lee and Ho Yeong Lim

    Citation: BMC Urology 2016 16:46

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  6. Content type: Research article

    The management of patients with renal cell carcinoma (RCC) with venous tumor thrombus (VTT) is challenging. We report our 15 year experience in the management of patients with RCC with VTT utilizing a multidis...

    Authors: Bishoy A. Gayed, Ramy Youssef, Oussama Darwish, Payal Kapur, Aditya Bagrodia, James Brugarolas, Ganesh Raj, J. Michael DiMaio, Arthur Sagalowsky and Vitaly Margulis

    Citation: BMC Urology 2016 16:43

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  7. Content type: Research article

    To validate the association between obesity and penile cancer at a population level, we conducted a matched case–control study linking the Iowa Department of Motor Vehicles Drivers’ License Database (DLD) with...

    Authors: Kerri T. Barnes, Bradley D. McDowell, Anna Button, Brian J. Smith, Charles F. Lynch and Amit Gupta

    Citation: BMC Urology 2016 16:42

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  8. Content type: Research article

    Renal cell carcinoma (RCC) associated with Xp11.2 translocation/TFE3 gene fusion (Xp11.2 RCC) is a rare subtype of RCC which is firstly described as a distinct entity in 2004 so that clinical characteristics o...

    Authors: Xiangming Cheng, Weidong Gan, Gutian Zhang, Xiaogong Li and Hongqian Guo

    Citation: BMC Urology 2016 16:40

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  9. Content type: Research article

    The standard of care in patients with suspected prostate cancer (PCa) is systematic prostate biopsies. This approach leads to unnecessary biopsies in patients without PCa and also to the detection of clinical ...

    Authors: Yngve Nygård, Svein A. Haukaas, Ole J. Halvorsen, Karsten Gravdal, Jannicke Frugård, Lars A. Akslen and Christian Beisland

    Citation: BMC Urology 2016 16:39

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  10. Content type: Research article

    The currently recommended treatment algorithm for patients with advanced renal cell carcinoma who fail the first-line targeted therapy does not normally include pazopanib as a second-line treatment option. It ...

    Authors: Victor C. Kok and Jung-Tsung Kuo

    Citation: BMC Urology 2016 16:34

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  11. Content type: Research article

    Spectrum effects refer to the phenomenon that test performance varies across subgroups of a population. When spectrum effects occur during diagnostic testing for cancer, difficult patient misdiagnoses can occu...

    Authors: Ajay Gopalakrishna, Thomas A. Longo, Joseph J. Fantony, Richmond Owusu, Wen-Chi Foo, Rajesh Dash and Brant A. Inman

    Citation: BMC Urology 2016 16:30

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  12. Content type: Research article

    We propose to improve the prognostic assessment after radical prostatectomy (RP) by dividing high-risk prostate cancer (hrPCa) (according to the d’Amico classification) into subgroups combining 1, 2 or 3 crite...

    Authors: Jean-Baptiste Beauval, Mathieu Roumiguié, Thomas Filleron, Thibaut Benoit, Alexandre de la Taille, Bernard Malavaud, Laurent Salomon, Michel Soulié and Guillaume Ploussard

    Citation: BMC Urology 2016 16:26

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  13. Content type: Research article

    Previous studies have demonstrated an association between prostate-specific antigen (PSA) kinetics and predictive value for treatment outcomes. Abiraterone acetate (AA) is a newly approved cytochrome-P450C17 i...

    Authors: Masahiko Nakayama, Hisanori Kobayashi, Tomihiro Takahara, Ryo Oyama, Keiichiro Imanaka and Kazutake Yoshizawa

    Citation: BMC Urology 2016 16:27

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  14. Content type: Research article

    Intestinal metaplasia of the bladder is an uncommon glandular proliferation. We examined a large series of intestinal metaplasia for the clinicopathological features and discuss the significance of this lesion.

    Authors: Zhixiang Xin, Chenhui Zhao, Tao Huang, Zhaohui Zhang, Chenlong Chu, Caifeng Lu, Min Wu and Wenlong Zhou

    Citation: BMC Urology 2016 16:24

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  15. Content type: Research article

    [−2]proPSA and its derivatives have an higher diagnostic accuracy than PSA in predicting prostate cancer (PCa). In alternative to PSA, ultrasensitive PSA (uPSA) and [−2]proPSA could be potentially useful in re...

    Authors: S. De Luca, R. Passera, A. Sottile, C. Fiori, R. M. Scarpa and F. Porpiglia

    Citation: BMC Urology 2016 16:14

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  16. Content type: Research article

    A possible role for prostate cancer in Lynch syndrome has been debated based on observations of mismatch-repair defective tumors and reports of an increased risk of prostate cancer in mutation carriers. Potent...

    Authors: Mev Dominguez-Valentin, Patrick Joost, Christina Therkildsen, Mats Jonsson, Eva Rambech and Mef Nilbert

    Citation: BMC Urology 2016 16:15

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  17. Content type: Research article

    There is much interest in confirming whether the efficacy of abiraterone acetate (AA) demonstrated within the trial setting is reproducible in routine clinical practice. We report the clinical outcome of metas...

    Authors: Darren M. C. Poon, Kuen Chan, S. H. Lee, T. W. Chan, Henry Sze, Eric K. C. Lee, Daisy Lam and Michelle F. T. Chan

    Citation: BMC Urology 2016 16:12

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  18. Content type: Research article

    While novel drugs have been developed, docetaxel remains one of the standard initial systemic therapies for castration-resistant prostate cancer (CRPC) patients. Despite the excellent anti-tumor effect of doce...

    Authors: Shimpei Yamashita, Yasuo Kohjimoto, Takashi Iguchi, Hiroyuki Koike, Hiroki Kusumoto, Akinori Iba, Kazuro Kikkawa, Yoshiki Kodama, Nagahide Matsumura and Isao Hara

    Citation: BMC Urology 2016 16:13

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