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Urological oncology

This section considers clinical studies relevant to oncological disorders in urology

Page 4 of 6

  1. Up to a fifth of patients diagnosed with prostate cancer (PC) will develop castration-resistant prostate cancer (CRPC), which has been associated with a poor prognosis. The aim of this study was to consider th...

    Authors: Hiroji Uemura, Nobuaki Matsubara, Go Kimura, Akito Yamaguchi, Dianne Athene Ledesma, Marco DiBonaventura, Ateesha F. Mohamed, Enrique Basurto, Ian McKinnon, Ed Wang, Kristen Concialdi, Aya Narimatsu and Yasuko Aitoku

    Citation: BMC Urology 2016 16:63

    Content type: Research article

    Published on:

    The Erratum to this article has been published in BMC Urology 2017 17:20

  2. The aim was to evaluate cancer-specific survival (CSS) and overall survival (OS) in patients with prostate cancer (PCa) recurrence who underwent salvage extended pelvic lymph node dissection (ePLND), taking in...

    Authors: Daniar K. Osmonov, Alexey V. Aksenov, David Trick, Carsten M. Naumann, Moritz F. Hamann, Amr Abou Faddan and Klaus-Peter Jünemann

    Citation: BMC Urology 2016 16:56

    Content type: Research article

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  3. Methylation of the tumor suppressor gene H-cadherin (CDH13) has been reported in many cancers. However, the clinical effect of the CDH13 methylation status of patients with bladder cancer remains to be clarified.

    Authors: Feng Chen, Tao Huang, Yu Ren, Junjun Wei, Zhongguan Lou, Xue Wang, Xiaoxiao Fan, Yirun Chen, Guobin Weng and Xuping Yao

    Citation: BMC Urology 2016 16:52

    Content type: Research article

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  4. Androgen deprivation therapy (ADT) is an effective palliation treatment in men with advanced prostate cancer (PC). However, ADT has well documented side effects that could alter the patient’s health-related qu...

    Authors: Nishi Karunasinghe, Yifei Zhu, Dug Yeo Han, Katja Lange, Shuotun Zhu, Alice Wang, Stephanie Ellett, Jonathan Masters, Megan Goudie, Justin Keogh, Benji Benjamin, Michael Holmes and Lynnette R. Ferguson

    Citation: BMC Urology 2016 16:48

    Content type: Research article

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  5. The guidelines of the European Association of Urologists (EAU), of the German Society of Nuclear Medicine (DGN), and the European Society for Medical Oncology (ESMO) recommend sentinel lymph node biopsy (SLNB)...

    Authors: Ulf Lützen, Carsten Maik Naumann, Jens Dischinger, Marlies Marx, René Baumann, Yi Zhao, Michael Jüptner, Daniar Osmonov, Katrin Bothe, Klaus-Peter Jünemann and Maaz Zuhayra

    Citation: BMC Urology 2016 16:47

    Content type: Research article

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  6. The efficacy and/or tolerability of pazopanib in patients with metastatic renal cell carcinoma (mRCC) have been found to differ in Western and Asian populations. This retrospective multicenter study analyzed t...

    Authors: Moon Jin Kim, Se Hoon Park, Jae-Lyun Lee, Se-Hoon Lee, Su Jin Lee and Ho Yeong Lim

    Citation: BMC Urology 2016 16:46

    Content type: Research article

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  7. The management of patients with renal cell carcinoma (RCC) with venous tumor thrombus (VTT) is challenging. We report our 15 year experience in the management of patients with RCC with VTT utilizing a multidis...

    Authors: Bishoy A. Gayed, Ramy Youssef, Oussama Darwish, Payal Kapur, Aditya Bagrodia, James Brugarolas, Ganesh Raj, J. Michael DiMaio, Arthur Sagalowsky and Vitaly Margulis

    Citation: BMC Urology 2016 16:43

    Content type: Research article

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  8. To validate the association between obesity and penile cancer at a population level, we conducted a matched case–control study linking the Iowa Department of Motor Vehicles Drivers’ License Database (DLD) with...

    Authors: Kerri T. Barnes, Bradley D. McDowell, Anna Button, Brian J. Smith, Charles F. Lynch and Amit Gupta

    Citation: BMC Urology 2016 16:42

    Content type: Research article

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  9. Renal cell carcinoma (RCC) associated with Xp11.2 translocation/TFE3 gene fusion (Xp11.2 RCC) is a rare subtype of RCC which is firstly described as a distinct entity in 2004 so that clinical characteristics o...

    Authors: Xiangming Cheng, Weidong Gan, Gutian Zhang, Xiaogong Li and Hongqian Guo

    Citation: BMC Urology 2016 16:40

    Content type: Research article

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  10. The standard of care in patients with suspected prostate cancer (PCa) is systematic prostate biopsies. This approach leads to unnecessary biopsies in patients without PCa and also to the detection of clinical ...

    Authors: Yngve Nygård, Svein A. Haukaas, Ole J. Halvorsen, Karsten Gravdal, Jannicke Frugård, Lars A. Akslen and Christian Beisland

    Citation: BMC Urology 2016 16:39

    Content type: Research article

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  11. The currently recommended treatment algorithm for patients with advanced renal cell carcinoma who fail the first-line targeted therapy does not normally include pazopanib as a second-line treatment option. It ...

    Authors: Victor C. Kok and Jung-Tsung Kuo

    Citation: BMC Urology 2016 16:34

    Content type: Research article

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  12. Spectrum effects refer to the phenomenon that test performance varies across subgroups of a population. When spectrum effects occur during diagnostic testing for cancer, difficult patient misdiagnoses can occu...

    Authors: Ajay Gopalakrishna, Thomas A. Longo, Joseph J. Fantony, Richmond Owusu, Wen-Chi Foo, Rajesh Dash and Brant A. Inman

    Citation: BMC Urology 2016 16:30

    Content type: Research article

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  13. Previous studies have demonstrated an association between prostate-specific antigen (PSA) kinetics and predictive value for treatment outcomes. Abiraterone acetate (AA) is a newly approved cytochrome-P450C17 i...

    Authors: Masahiko Nakayama, Hisanori Kobayashi, Tomihiro Takahara, Ryo Oyama, Keiichiro Imanaka and Kazutake Yoshizawa

    Citation: BMC Urology 2016 16:27

    Content type: Research article

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  14. We propose to improve the prognostic assessment after radical prostatectomy (RP) by dividing high-risk prostate cancer (hrPCa) (according to the d’Amico classification) into subgroups combining 1, 2 or 3 crite...

    Authors: Jean-Baptiste Beauval, Mathieu Roumiguié, Thomas Filleron, Thibaut Benoit, Alexandre de la Taille, Bernard Malavaud, Laurent Salomon, Michel Soulié and Guillaume Ploussard

    Citation: BMC Urology 2016 16:26

    Content type: Research article

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  15. Intestinal metaplasia of the bladder is an uncommon glandular proliferation. We examined a large series of intestinal metaplasia for the clinicopathological features and discuss the significance of this lesion.

    Authors: Zhixiang Xin, Chenhui Zhao, Tao Huang, Zhaohui Zhang, Chenlong Chu, Caifeng Lu, Min Wu and Wenlong Zhou

    Citation: BMC Urology 2016 16:24

    Content type: Research article

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  16. A possible role for prostate cancer in Lynch syndrome has been debated based on observations of mismatch-repair defective tumors and reports of an increased risk of prostate cancer in mutation carriers. Potent...

    Authors: Mev Dominguez-Valentin, Patrick Joost, Christina Therkildsen, Mats Jonsson, Eva Rambech and Mef Nilbert

    Citation: BMC Urology 2016 16:15

    Content type: Research article

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  17. [−2]proPSA and its derivatives have an higher diagnostic accuracy than PSA in predicting prostate cancer (PCa). In alternative to PSA, ultrasensitive PSA (uPSA) and [−2]proPSA could be potentially useful in re...

    Authors: S. De Luca, R. Passera, A. Sottile, C. Fiori, R. M. Scarpa and F. Porpiglia

    Citation: BMC Urology 2016 16:14

    Content type: Research article

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  18. While novel drugs have been developed, docetaxel remains one of the standard initial systemic therapies for castration-resistant prostate cancer (CRPC) patients. Despite the excellent anti-tumor effect of doce...

    Authors: Shimpei Yamashita, Yasuo Kohjimoto, Takashi Iguchi, Hiroyuki Koike, Hiroki Kusumoto, Akinori Iba, Kazuro Kikkawa, Yoshiki Kodama, Nagahide Matsumura and Isao Hara

    Citation: BMC Urology 2016 16:13

    Content type: Research article

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  19. There is much interest in confirming whether the efficacy of abiraterone acetate (AA) demonstrated within the trial setting is reproducible in routine clinical practice. We report the clinical outcome of metas...

    Authors: Darren M. C. Poon, Kuen Chan, S. H. Lee, T. W. Chan, Henry Sze, Eric K. C. Lee, Daisy Lam and Michelle F. T. Chan

    Citation: BMC Urology 2016 16:12

    Content type: Research article

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  20. The high false negative rates for initial prostate biopsies refer a large number of the men for repeat biopsies each year. Therefore, biomarkers associated with high risk of the presence of malignancy in histo...

    Authors: Saeid Alinezhad, Riina-Minna Väänänen, Natalia Tong Ochoa, Emily A. Vertosick, Anders Bjartell, Peter J Boström, Pekka Taimen and Kim Pettersson

    Citation: BMC Urology 2016 16:10

    Content type: Research article

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  21. Lymphovascular invasion (LVI) is an important step in the process of tumor dissemination and metastasis outside the primary organ, but the relationship between LVI and the prognosis of T1 non-muscle invasive b...

    Authors: Keishiro Fukumoto, Eiji Kikuchi, Shuji Mikami, Akira Miyajima and Mototsugu Oya

    Citation: BMC Urology 2016 16:5

    Content type: Research article

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  22. Measurement of the prostate specific antigen (PSA) remains an important tool in prostate cancer (PC) diagnosis. Due to limited availability of laboratory devices in an outpatient setting, compact and easy-to-h...

    Authors: Steffen Rausch, Joerg Hennenlotter, Josef Wiesenreiter, Andrea Hohneder, Julian Heinkele, Christian Schwentner, Arnulf Stenzl and Tilman Todenhöfer

    Citation: BMC Urology 2016 16:4

    Content type: Research article

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  23. Current therapies for advanced renal cell carcinoma (RCC) have low cure rates or significant side effects. It has been reported that complexes composed of interleukin (IL)-2 and stimulating anti-IL-2 antibody ...

    Authors: Kyu-Hyun Han, Ki Won Kim, Ji-Jing Yan, Jae-Ghi Lee, Eun Mi Lee, Miyeon Han, Eun Jin Cho, Seong Sik Kang, Hye Jin Lim, Tai Yeon Koo, Curie Ahn and Jaeseok Yang

    Citation: BMC Urology 2016 16:2

    Content type: Research article

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  24. The American Urological Association (AUA) changed their Prostate-Specific Antigen (PSA) screening guidelines in 2013 to not recommend testing in men under 55 years of age without significant risk factors (such...

    Authors: Nandu D. Dantanarayana, Tania Hossack, Paul Cozzi, Andrew Brooks, Howard Lau, Warick Delprado and Manish I. Patel

    Citation: BMC Urology 2015 15:124

    Content type: Research article

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  25. Prostate cancer is the second most common diagnosed cancer in men. Due to the low specificity of current diagnosis methods for detecting prostate cancer, identification of new biomarkers is highly desirable. T...

    Authors: Jin Huang, Kathleen H. Reilly, Hui-Zhen Zhang and Hai-Bo Wang

    Citation: BMC Urology 2015 15:118

    Content type: Research article

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  26. Prostate cancer remains the most common cancer in men. Qualitative or semi-quantitative immunochromatographic measurements of prostate specific antigen (PSA) have been shown to be simple, noninvasive and feasi...

    Authors: Cheng-Ching Wu, Hung-Yu Lin, Chao-Ping Wang, Li-Fen Lu, Teng-Hung Yu, Wei-Chin Hung, Jer-Yiing Houng, Fu-Mei Chung, Yau-Jiunn Lee and Jin-Jia Hu

    Citation: BMC Urology 2015 15:109

    Content type: Research article

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  27. To investigate the efficacy of initial biopsy or transurethral resection of bladder tumor for detecting histological variants on radical cystectomy and to assess the prognostic significance of variant histolog...

    Authors: Peng Ge, Zi-Cheng Wang, Xi Yu, Jian Lin and Qun He

    Citation: BMC Urology 2015 15:46

    Content type: Research article

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  28. Urothelial carcinoma (UC) is a common cancer affecting many patients in the United States. Nephroureterectomy remains the gold standard for the treatment of high grade upper tract disease or low grade tumors t...

    Authors: Michael A. Moriarty, Matthew A. Uhlman, Megan T. Bing, Michael A. O’Donnell, James A. Brown, Chad R. Tracy, Sundeep Deorah, Kenneth G. Nepple and Amit Gupta

    Citation: BMC Urology 2015 15:45

    Content type: Research article

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  29. Adrenocortical carcinoma (ACC) is aggressive, but rare tumours that have not been sufficiently studied. The aim of our study was to present the demographic and clinical characteristics of patients with ACC, to...

    Authors: Zlatibor Loncar, Vladimir Djukic, Vladan Zivaljevic, Tatjana Pekmezovic, Aleksandar Diklic, Svetislav Tatic, Dusko Dundjerovic, Branislav Olujic, Nikola Slijepcevic and Ivan Paunovic

    Citation: BMC Urology 2015 15:43

    Content type: Research article

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  30. Clinical benefit of axitinib as a first line agent to treat patients with metastatic renal cell carcinoma (mRCC), or locally advanced renal cell carcinoma (RCC) have not been clearly demonstrated. The aim of t...

    Authors: Takuya Koie, Chikara Ohyama, Takahiro Yoneyama, Hayato Yamamoto, Atsushi Imai, Shingo Hatakeyama, Yasuhiro Hashimoto, Tohru Yoneyama, Yuki Tobisawa and Kazuyuki Mori

    Citation: BMC Urology 2015 15:32

    Content type: Research article

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  31. This study describes and compares health-related quality of life (HRQOL) of prostate cancer patients who received either radical prostatectomy (nerve-sparing, nsRP, or non-nerve-sparing, nnsRP) or radiotherapy...

    Authors: Nora Eisemann, Sandra Nolte, Maike Schnoor, Alexander Katalinic, Volker Rohde and Annika Waldmann

    Citation: BMC Urology 2015 15:28

    Content type: Research article

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  32. Radical prostatectomy is a standard surgical treatment of clinically localized prostate cancer. Margin status has been found to be an independent predictor of biochemical recurrence (BCR) after open radical pr...

    Authors: Ryuta Tanimoto, Yomi Fashola, Kymora B Scotland, Anne E Calvaresi, Leonard G Gomella, Edouard J Trabulsi and Costas D Lallas

    Citation: BMC Urology 2015 15:27

    Content type: Research article

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  33. To assess pathological correlations and temporal trends of Angiopoietin-2 (ANGPT2), vascular endothelial growth factor (VEGF) and M2 Pyruvate kinase (TuM2PK), markers of tumor vascular development and metaboli...

    Authors: Bishoy A Gayed, Jessica Gillen, Alana Christie, Samuel Peña-Llopis, Xian-Jin Xie, Jingsheng Yan, Jose A Karam, Ganesh Raj, Arthur I Sagalowsky, Yair Lotan, Vitaly Margulis and James Brugarolas

    Citation: BMC Urology 2015 15:24

    Content type: Research article

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  34. Hematuria can be symptomatic of urothelial carcinoma (UC) and ruling out patients with benign causes during primary evaluation is challenging. Patients with hematuria undergoing urological work-ups place signi...

    Authors: Laimonis Kavalieris, Paul J O’Sullivan, James M Suttie, Brent K Pownall, Peter J Gilling, Christophe Chemasle and David G Darling

    Citation: BMC Urology 2015 15:23

    Content type: Research article

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  35. Major life-threatening complications secondary to cisplatin-based chemotherapy are rare in patients with testicular germ cell tumour (GCT). The incidence of complications increases with dosage of chemotherapy ...

    Authors: Klaus-Peter Dieckmann, Petra Anheuser, Ralf Gehrckens, Sven Philip Aries, Raphael Ikogho and Wiebke Hollburg

    Citation: BMC Urology 2015 15:21

    Content type: Case report

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  36. Metastasis to penis usually arises from genitourinary organs, but in rare cases, metastasis comes from the sigmoid colon. Furthermore, very few cases of penile metastasis of primary sigmoid colon carcinoma hav...

    Authors: Zhengbang Dong, Chao Qin, Qijie Zhang, Lei Zhang, Haijing Yang, Jingdong Zhang and Fei Wang

    Citation: BMC Urology 2015 15:20

    Content type: Case report

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  37. The loss of a testicle to cancer involves much emotional impact to young males. Little is known about the number of patients with testicular germ cell tumour (GCT) who would accept a testicular prosthesis. Als...

    Authors: Klaus-Peter Dieckmann, Petra Anheuser, Stefan Schmidt, Benjamin Soyka-Hundt, Uwe Pichlmeier, Philipp Schriefer, Cord Matthies, Michael Hartmann and Christian G Ruf

    Citation: BMC Urology 2015 15:16

    Content type: Research article

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  38. More than 429,000 patients worldwide are diagnosed with bladder cancer each year and muscle-invasive bladder cancer has an especially poor outcome. The median age at diagnosis is over 70 years, and many patien...

    Authors: Vicente Guillem, Miguel Angel Climent, Javier Cassinello, Emilio Esteban, Daniel Castellano, José Luis González-Larriba, Pablo Maroto and Carlos Camps

    Citation: BMC Urology 2015 15:15

    Content type: Case report

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  39. The human papillomavirus (HPV) prevalence in males has been reported to be between 3.6% and 84%, depending specially on the socioeconomic status. HPV infection has been related as a risk factor for penile canc...

    Authors: Isaura Danielli Borges de Sousa, Flávia Castello Branco Vidal, João Paulo Castello Branco Vidal, George Castro Figueira de Mello, Maria do Desterro Soares Brandão Nascimento and Luciane Maria Oliveira Brito

    Citation: BMC Urology 2015 15:13

    Content type: Research article

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  40. Adenocarcinoma of the urinary bladder is a rare malignancy. Radical surgery is suggested as the best available treatment for early-stage disease, but there is currently no consensus on standard chemotherapy re...

    Authors: Bin Yu, Jin Zhou, Hongzhou Cai, Ting Xu, Zicheng Xu, Qing Zou and Min Gu

    Citation: BMC Urology 2015 15:3

    Content type: Research article

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  41. Papillary renal cell carcinoma (pRCC) is a mixed group of tumors that constitutes about 15-20% of all renal cortical cancers. Strong enhancement on computerized tomography (CT) is a feature of clear cell, but ...

    Authors: Shaheen Alanee, Danuta I Dynda, Patrick Hemmer and Bradley Schwartz

    Citation: BMC Urology 2014 14:102

    Content type: Case report

    Published on:

  42. Partial nephrectomy has been underutilized in the United States. We investigated national trends in partial nephrectomy (PN) utilization before and after publication of the American Urological Association (AUA...

    Authors: Michael A Liss, Song Wang, Kerrin Palazzi, Ramzi Jabaji, Nishant Patel, Hak J Lee, J Kellogg Parsons and Ithaar H Derweesh

    Citation: BMC Urology 2014 14:101

    Content type: Research article

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  • BMC Urology works with with Cochrane Urology in providing our authors with expert advice on systematic reviews and meta-analyses

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