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Voiding dysfunction

Section edited by Cosimo de Nunzio and Stephen Kraus

This section considers submissions relating to the management of urological male and female voiding dysfunction, including neurological disorders and prostatic diseases. (NOTE: Articles dealing with the diagnosis or treatment of prostate cancer should be submitted to the "Urological oncology" section)

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  1. Content type: Research article

    Adenosine-5′-triphosphate (ATP) is a neurotransmitter and inflammatory cytokine implicated in the pathophysiology of lower urinary tract disease. ATP additionally reflects microbial biomass thus has potential ...

    Authors: Kiren Gill, Harry Horsley, Anthony S Kupelian, Gianluca Baio, Maria De Iorio, Sanchutha Sathiananamoorthy, Rajvinder Khasriya, Jennifer L Rohn, Scott S Wildman and James Malone-Lee

    Citation: BMC Urology 2015 15:7

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  2. Content type: Research article

    To investigate the expression of parathyroid hormone (PTH)/PTH-related peptide (PTHrP) receptor 1 (PTH1R) in clinical specimens of normal and diseased bladders. PTHrP is a unique stretch-induced endogenous det...

    Authors: Nobuyuki Nishikawa, Rie Yago, Yuichiro Yamazaki, Hiromitsu Negoro, Mari Suzuki, Masaaki Imamura, Yoshinobu Toda, Kazunari Tanabe, Osamu Ogawa and Akihiro Kanematsu

    Citation: BMC Urology 2015 15:2

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  3. Content type: Research article

    Aim of this study was to make a comparison between penile cuff test (PCT) and standard pressure-flow study (PFS) in the preoperative evaluation of patients candidates for trans-urethral resection of prostate (...

    Authors: Daniele Bianchi, Angelo Di Santo, Gabriele Gaziev, Roberto Miano, Stefania Musco, Giuseppe Vespasiani and Enrico Finazzi Agrò

    Citation: BMC Urology 2014 14:103

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  4. Content type: Research article

    Radical prostatectomy (RP) is the most common treatment for patients with localized prostate cancer. Urinary incontinence (UI) is a significant bothersome sequela after radical prostatectomy that may dramatica...

    Authors: Wei Wang, Qing Mei Huang, Feng Ping Liu and Qi Qi Mao

    Citation: BMC Urology 2014 14:99

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  5. Content type: Case report

    Acute hypokalaemic paralysis is characterised by acute flaccid muscle weakness and has a complex aetiological spectrum. Herein we report, for the first time, a case of unilateral adrenal hyperplasia accompanie...

    Authors: Bo Yang, Yuan Yang, Wenling Tu, Ying Shen and Qiang Dong

    Citation: BMC Urology 2014 14:96

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  6. Content type: Case report

    Irrigation or washouts of the bladder are usually performed in various clinical settings. In the 1980s Elliot and colleagues argued that urothelial damage could occur after washouts and irrigations of the blad...

    Authors: Marco Di Paolo, Valentina Bugelli, Alessandro Di Luca and Emanuela Turillazzi

    Citation: BMC Urology 2014 14:91

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  7. Content type: Research article

    The causality of overactive bladder syndrome (OAB) is still not fully understood. Several studies indicate a significant increase of prostaglandin E2 (PGE2) in patients with OAB. However, in order to clarify w...

    Authors: Axel Hegele, Sonja Knippschild, Carsten Frohme, Jörg Hänze, Peter Olbert and Rainer Hofmann

    Citation: BMC Urology 2014 14:85

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  8. Content type: Research article

    Overactive bladder (OAB)/ storage lower urinary tract symptoms (LUTS) have a high prevalence affecting up to 90% of men over 80 years. The role of sufficient therapies appears crucial. In the present review, w...

    Authors: Mauro Gacci, Giacomo Novara, Cosimo De Nunzio, Andrea Tubaro, Riccardo Schiavina, Eugenio Brunocilla, Arcangelo Sebastianelli, Matteo Salvi, Matthias Oelke, Stavros Gravas, Marco Carini and Sergio Serni

    Citation: BMC Urology 2014 14:84

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  9. Content type: Study protocol

    The control of the lower urinary tract is a complex, multilevel process involving both the peripheral and central nervous system. Due to lesions of the neuraxis, most spinal cord injury patients suffer from ne...

    Authors: Lorenz Leitner, Matthias Walter, Patrick Freund, Ulrich Mehnert, Lars Michels, Spyros Kollias and Thomas M Kessler

    Citation: BMC Urology 2014 14:68

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  10. Content type: Research article

    We have observed different clinical responses to botulinum toxin A (BTX-A) in patients who had similar urodynamic parameters before the procedure. Furthermore, some bladders evaluated by cystography and cystos...

    Authors: Ronaldo Alvarenga Álvares, Ivana Duval Araújo and Marcelo Dias Sanches

    Citation: BMC Urology 2014 14:66

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  11. Content type: Study protocol

    Sacral neuromodulation has become a well-established and widely accepted treatment for refractory non-neurogenic lower urinary tract dysfunction, but its value in patients with a neurological cause is unclear....

    Authors: Stephanie C Knüpfer, Martina D Liechti, Livio Mordasini, Dominik Abt, Daniel S Engeler, Jens Wöllner, Jürgen Pannek, Bernhard Kiss, Fiona C Burkhard, Marc P Schneider, Elena Miramontes, Alfons G Kessels, Lucas M Bachmann and Thomas M Kessler

    Citation: BMC Urology 2014 14:65

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  12. Content type: Review

    Bioactive compounds from plants (i.e., Serenoa repens) are often used in medicine in the treatment of several pathologies, among which benign prostatic hyperplasia (BPH) associated to lower urinary tract symptoms...

    Authors: Celeste De Monte, Simone Carradori, Arianna Granese, Giovanni Battista Di Pierro, Costantino Leonardo and Cosimo De Nunzio

    Citation: BMC Urology 2014 14:63

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  13. Content type: Research article

    The efficacy of medical treatment among obese men with lower urinary tract symptoms (LUTS) has been less clear, especially regarding the improvement of QoL. We aimed to investigate the difference in efficacy a...

    Authors: Jae Heon Kim, Hoon Choi, Hwa Yeon Sun, Seung Whan Doo, Jong Hyun Yoon, Won Jae Yang, Byung Wook Yoo, Joyce Mary Kim, Soon-Sun Kwon, Eun Seop Song, Hong Jun Lee, Ik Sung Lim and Yun Seob Song

    Citation: BMC Urology 2014 14:60

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  14. Content type: Research article

    Bacterial prostatitis (BP) is a common condition accounting responsible for about 5-10% of all prostatitis cases; chronic bacterial prostatitis (CBP) classified as type II, are less common but is a condition t...

    Authors: Gian Maria Busetto, Riccardo Giovannone, Matteo Ferro, Stefano Tricarico, Francesco Del Giudice, Deliu Victor Matei, Ottavio De Cobelli, Vincenzo Gentile and Ettore De Berardinis

    Citation: BMC Urology 2014 14:53

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  15. Content type: Technical advance

    Botulinum toxin A (BoNT-A) is a new treatment modality in various causes of bladder dysfunction; like neurogenic detrusor overactivity and overactive bladder. The best technique of administrating BoNT-A in pat...

    Authors: Janneke IM van Uhm, Goedele MA Beckers, Willem J van der Laarse, Eric JH Meuleman, Albert A Geldof and Jakko A Nieuwenhuijzen

    Citation: BMC Urology 2014 14:37

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  16. Content type: Research article

    Only limited data are available on the outcome of tension-free obturator tape (TOT) procedures in overweight and obese women. We would like to verify the objective and subjective outcomes of TOT in women with ...

    Authors: Carsten Frohme, Friederike Ludt, Zoltan Varga, Peter J Olbert, Rainer Hofmann and Axel Hegele

    Citation: BMC Urology 2014 14:20

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  17. Content type: Case report

    Hem-o-lok clips are widely used during robot-assisted and laparoscopic radical prostatectomy to control the lateral pedicles. There are a few reports of hem-o-lok clip migration into the bladder or vesico-uret...

    Authors: Luigi Cormio, Paolo Massenio, Giuseppe Lucarelli, Giuseppe Di Fino, Oscar Selvaggio, Salvatore Micali and Giuseppe Carrieri

    Citation: BMC Urology 2014 14:21

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  18. Content type: Research article

    Higher physical activity levels are continence-protective in non-prostate cancer populations. Primary aims of this study were to investigate changes in physical activity levels over the perioperative period in...

    Authors: Sean F Mungovan, Bregtje P Huijbers, Andrew D Hirschhorn and Manish I Patel

    Citation: BMC Urology 2013 13:67

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  19. Content type: Research article

    Percutaneous Tibial Nerve Stimulation (PTNS) has been proposed for the treatment of overactive bladder syndrome (OAB), non-obstructive urinary retention (NOUR), neurogenic bladder, paediatric voiding dysfuncti...

    Authors: Gabriele Gaziev, Luca Topazio, Valerio Iacovelli, Anastasios Asimakopoulos, Angelo Di Santo, Cosimo De Nunzio and Enrico Finazzi-Agrò

    Citation: BMC Urology 2013 13:61

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  20. Content type: Research article

    To determine whether neuregulin-1(NRG-1) is a potential new biomarker of overactive bladder (OAB) induced by partial urethral obstruction in a rat model of OAB and to evaluate the urothelium as a therapeutic t...

    Authors: Hoon Jang, Dong Seok Han and Seung Mo Yuk

    Citation: BMC Urology 2013 13:54

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  21. Content type: Technical advance

    Sacral neuromodulation operations have usually been performed based on 2D fluoro images. However, sacral nerve stimulation lead implantation may be challenging when the normal anatomy is confused by obesity or...

    Authors: Pekka A Hellström, Jani Katisko, Pertti Finnilä and Markku H Vaarala

    Citation: BMC Urology 2013 13:48

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  22. Content type: Research article

    Antimuscarinic agents are currently the predominant treatment option for the clinical management of the symptoms of overactive bladder (OAB). However, low rates of persistence with these agents highlight the n...

    Authors: Vik Khullar, Javier Cambronero, Javier C Angulo, Marianne Wooning, Mary Beth Blauwet, Caroline Dorrepaal and Nancy E Martin

    Citation: BMC Urology 2013 13:45

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  23. Content type: Research article

    Using the isovolumetric bladder rhythmic contraction (BRC) model in anesthetized rats, we have quantified the responsiveness to unilateral and bilateral stimulation of the L6 spinal nerve (SN) and characterize...

    Authors: Xin Su, Angela Nickles and Dwight E Nelson

    Citation: BMC Urology 2013 13:34

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  24. Content type: Research article

    Nocturia is defined as waking one or more times during the night due to the urge to void. Recently, the effectiveness of several sedatives and analgesics for nocturia has been reported. We herein investigated ...

    Authors: Takashi Kawahara, Satoshi Morita, Hiroki Ito, Hideyuki Terao, Ryoko Sakata, Hitoshi Ishiguro, Katsuyuki Tanaka, Hiroshi Miyamoto, Junichi Matsuzaki, Yoshinobu Kubota and Hiroji Uemura

    Citation: BMC Urology 2013 13:30

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  25. Content type: Research article

    The present study was aimed at determining the prophylactic efficacy of American cranberry (AC) extract (Cysticlean®) in women with recurrent symptomatic postcoital urinary tract infections (PCUTI), non-consum...

    Authors: Francisco Sánchez Ballester, Vicente Ruiz Vidal, Emilio López Alcina, Cristina Domenech Perez, Eva Escudero Fontano, Ana María Oltra Benavent, Ana Montoliu García and Marco Andrés Sobrón Bustamante

    Citation: BMC Urology 2013 13:28

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  26. Content type: Research article

    The objective of this study is to determine in a case series (four patients) how calcified deposits in renal papillae are associated with the development of calcium oxalate monohydrate (COM) papillary calculi.

    Authors: Fèlix Grases, Antonia Costa-Bauzá, Rafel M Prieto, Antonio Conte and Antonio Servera

    Citation: BMC Urology 2013 13:14

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  27. Content type: Case report

    Secondary urethral stone although rare, commonly arises from the kidneys, bladder or are seen in patients with urethral stricture. These stones are either found in the posterior or anterior urethra and do resu...

    Authors: Linus I Okeke, Augustine O Takure, Sikiru A Adebayo, Olukayode Y Oluyemi and Abimbola AA Oyelekan

    Citation: BMC Urology 2012 12:31

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  28. Content type: Research article

    Lower urinary tract symptoms (LUTS) in aging men are often associated with benign prostatic hyperplasia (BPH). While regulatory evaluations of treatment benefit require an assessment of specific symptoms, a si...

    Authors: Lars Viktrup, Risa P Hayes, Ping Wang and Wei Shen

    Citation: BMC Urology 2012 12:30

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  29. Content type: Research article

    The Patient Perception of Intensity of Urgency Scale (PPIUS) is a patient-reported outcome instrument intended to measure the intensity of urgency associated with each urinary or incontinence episode. The obje...

    Authors: Sherilyn M Notte, Thomas S Marshall, Misun Lee, Zalmai Hakimi, Isaac Odeyemi, Wen-Hung Chen and Dennis A Revicki

    Citation: BMC Urology 2012 12:26

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