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  1. Cisplatin (CP) or cis-diammine dichloroplatinum (II) is a platinum based standard antineoplastic drug which is used against variety of solid tumors and neoplasms. The present study aimed to evaluate the shield...

    Authors: Sarwat Jahan, Asma Munawar, Suhail Razak, Sara Anam, Qurat Ul Ain, Hizb Ullah, Tayyaba Afsar, Mahmoud Abulmeaty and Ali Almajwal

    Citation: BMC Urology 2018 18:107

    Content type: Research article

    Published on:

  2. Xp11.2 translocation renal cell carcinoma (RCC) is a rare variety of a kidney neoplasm. We report a case of bilateral Xp11.2 translocation RCC occurring metachronously and discuss this very rare entity with re...

    Authors: Takashi Karashima, Takahira Kuno, Naoto Kuroda, Hirofumi Satake, Satoshi Fukata, Masakazu Chikazawa, Chiaki Kawada, Ichiro Yamasaki, Taro Shuin, Makoto Hiroi and Keiji Inoue

    Citation: BMC Urology 2018 18:106

    Content type: Case report

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  3. The spontaneous regression of metastatic renal cell carcinoma is a rare phenomenon, with an estimated incidence of < 1%. We report a case of post-nephrectomy renal cell carcinoma adrenal metastasis, followed b...

    Authors: Ti-Yuan Yang, Wun-Rong Lin and Allen W. Chiu

    Citation: BMC Urology 2018 18:105

    Content type: Case report

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  4. Varicocele is known to be associated with infertility and sperm disorders. The exact cause of this ailment is not fully understood. There are limited numbers of studies where venous blood gases (VBGs) of varic...

    Authors: Khaleeq ur Rehman, Hafsa Zaneb, Abdul Basit Qureshi, Ahsan Numan, Muhammad Shahbaz Yousaf, Imtiaz Rabbani and Habib Rehman

    Citation: BMC Urology 2018 18:104

    Content type: Research article

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  7. Previous studies have shown that, compared with non-stone formers, stone formers have a higher papillary density measured with computer tomography (CT) scan. The effect of increased hydration on such papillary...

    Authors: Pietro Manuel Ferraro, Matteo Vittori, Giuseppe Macis, Alessandro D’Addessi, Gianmarco Lombardi, Claudia Palmisano, Jacopo Gervasoni, Aniello Primiano, Pier Francesco Bassi and Giovanni Gambaro

    Citation: BMC Urology 2018 18:101

    Content type: Research article

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  8. Epidermal growth factor receptor (EGFR) overexpression is believed to be associated with bladder cancer (BC) progression and poor clinical outcomes. In vivo studies have linked EGFR subcellular trafficking and...

    Authors: Ahmed M. Mansour, Mona Abdelrahim, Mahmoud Laymon, Mamdouh Elsherbeeny, Mohammed Sultan, Ahmed Shokeir, Ahmed Mosbah, Hassan Abol-Enein, Amira Awadalla, Eunho Cho, Vikram Sairam, Taeeun D. Park, Muhammad Shahid and Jayoung Kim

    Citation: BMC Urology 2018 18:100

    Content type: Research article

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  9. Warm ischemia (WI) and bleeding constitute the main challenges for surgeons during laparoscopic partial nephrectomy (LPN). Current literature on the use of lasers for cutting and coagulation remains scarce and...

    Authors: Martin Drerup, Ahmed Magdy, Martina Hager, Daniela Colleselli, Thomas Kunit, Lukas Lusuardi, Günter Janetschek and Michael Mitterberger

    Citation: BMC Urology 2018 18:99

    Content type: Research article

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  10. The diagnostic pathway for prostate cancer (PCa) is advancing towards an imaging-driven approach. Multiparametric magnetic resonance imaging, although increasingly used, has not shown sufficient accuracy to re...

    Authors: Christophe K. Mannaerts, Rogier R. Wildeboer, Arnoud W. Postema, Johanna Hagemann, Lars Budäus, Derya Tilki, Massimo Mischi, Hessel Wijkstra and Georg Salomon

    Citation: BMC Urology 2018 18:98

    Content type: Study protocol

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  11. Bladder cancers have been characterized as a tumor group in which the immunological response is relatively well preserved. Programmed death ligand 1 (PD-L1, B7-H1, CD274) has been shown to be expressed in seve...

    Authors: Takashi Kawahara, Yukari Ishiguro, Shinji Ohtake, Ikuma Kato, Yusuke Ito, Hiroki Ito, Kazuhide Makiyama, Keiichi Kondo, Yasuhide Miyoshi, Yasushi Yumura, Narihiko Hayashi, Hisashi Hasumi, Kimito Osaka, Kentaro Muraoka, Koji Izumi, Jun-ichi Teranishi…

    Citation: BMC Urology 2018 18:97

    Content type: Research article

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  13. Primary retroperitoneal lymph node dissection (RPLND) ultimately lost its role as the standard management of clinical stage (CS) 1 nonseminomatous (NS) testicular germ cell tumours (GCTs) in Europe when the Eu...

    Authors: K.-P. Dieckmann, P. Anheuser, M. Kulejewski, R. Gehrckens and B. Feyerabend

    Citation: BMC Urology 2018 18:95

    Content type: Research article

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  15. Intravesical Mitomycin-C (MMC) following transurethral resection of bladder tumor (TURBT), while efficacious, is associated with side effects and poor utilization. Continuous saline bladder irrigation (CSBI) h...

    Authors: Andrew T. Lenis, Kian Asanad, Maher Blaibel, Nicholas M. Donin and Karim Chamie

    Citation: BMC Urology 2018 18:93

    Content type: Research article

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  16. Prostatic artery embolization (PAE) has been proved effective in the treatment of lower urinary tracts (LUTS) secondary to benign prostatic hyperplasia (BPH) with low complications, and most of the them are du...

    Authors: Jin Long Zhang, Kai Yuan, Mao Qiang Wang, Jie Yu Yan, Yan Wang and Guo Dong Zhang

    Citation: BMC Urology 2018 18:92

    Content type: Research article

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  17. Radical cystectomy bears a considerable perioperative mortality risk particularly in elderly patients. In this study, we searched for predictors of perioperative and long-term competing (non-bladder cancer) mo...

    Authors: Michael Froehner, Rainer Koch, Matthias Hübler, Ulrike Heberling, Vladimir Novotny, Stefan Zastrow, Oliver W. Hakenberg and Manfred P. Wirth

    Citation: BMC Urology 2018 18:91

    Content type: Research article

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  18. This study aims to prospectively evaluate the ability of Neutrophil-to-Lymphocyte ratio (NLR) to forecast recurrence in patients with non-muscle invasive bladder cancer (NMIBC). This is a continuation of our t...

    Authors: Itamar Getzler, Zaher Bahouth, Ofer Nativ, Jacob Rubinstein and Sarel Halachmi

    Citation: BMC Urology 2018 18:90

    Content type: Research article

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  19. The goal of radical prostatectomy is to achieve the optimal balance between complete cancer removal and preserving a patient’s urinary and sexual function. Performing a wider excision of peri-prostatic tissue ...

    Authors: R. H. Breau, R. M. Kumar, L. T. Lavallee, I. Cagiannos, C. Morash, M. Horrigan, S. Cnossen, R. Mallick, D. Stacey, M. Fung-Kee-Fung, R. Morash, J. Smylie, K. Witiuk and D. A. Fergusson

    Citation: BMC Urology 2018 18:89

    Content type: Study protocol

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  20. Wilms tumor is the most common renal tumor of childhood. Duplication of the inferior vena cava is an uncommon anomaly. In the present study, we present a case of Wilms tumor with the inferior vena cava duplica...

    Authors: Feng Guo, Tianyou Li, Wei Liu, Gang Wang, Rui Ma and Rongde Wu

    Citation: BMC Urology 2018 18:88

    Content type: Case report

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  21. The impact of number of endoscopic enucleation of the prostate techniques (holmium laser enucleation - HoLEP for example) on erectile function have already been investigated. However, the thulium-fiber laser, ...

    Authors: Dmitry Enikeev, Petr Glybochko, Leonid Rapoport, Zhamshid Okhunov, Mitchel O’Leary, Natalya Potoldykova, Roman Sukhanov, Mikhail Enikeev, Ekaterina Laukhtina and Mark Taratkin

    Citation: BMC Urology 2018 18:87

    Content type: Research article

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  22. The tumor draining lymph node concept was first described in penile cancer for staging. Immunohistochemistry and histopathology evaluations are routinely used in clinical practice to examine lymph nodes for me...

    Authors: Lu Zhang, Jin Hu, A. Ali Zirakzadeh, Jesper Rosvall, Mats Hedlund, Ping Sheng Hu, Robert P.A. Wallin, Amir Sherif and Ola Winqvist

    Citation: BMC Urology 2018 18:86

    Content type: Research article

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  23. The introduction of foreign bodies in the female urethra for auto-erotic stimulation or in case of psychiatric disorders is not uncommon. The occurrence of intravesical migration of these objects makes it nece...

    Authors: Andrea Mogorovich, Cesare Selli, Alessio Tognarelli, Francesca Manassero and Maurizio De Maria

    Citation: BMC Urology 2018 18:85

    Content type: Case report

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  24. It has been highlighted that in the original article [1] there was a typesetting mistake in the Results – NNT in Strive section. This Correction article states the incorrect and correct sentence.

    Authors: Neil M Schultz, Neal D Shore, Simon Chowdhury, Laurence H Klotz, Raoul S Concepcion, David F Penson, Lawrence I Karsh, Hongbo Yang, Bruce A Brown, Arie Barlev and Scott C Flanders

    Citation: BMC Urology 2018 18:84

    Content type: Correction

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    The original article was published in BMC Urology 2018 18:77

  26. Immediate early response gene 3 (IER3) is a stress-inducible gene, which exerts diverse effects in regulating cell apoptosis and cell cycle. Growing evidence shows that IER3 functions either as an oncogene or ...

    Authors: Jianheng Ye, Yanqiong Zhang, Zhiduan Cai, Minyao Jiang, Bowei Li, Guo Chen, Yanru Zeng, Yuxiang Liang, Shulin Wu, Zongwei Wang, Huichan He, Weide Zhong and Chin-Lee Wu

    Citation: BMC Urology 2018 18:82

    Content type: Research article

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  27. Most patients with advanced prostate cancer develop bone metastases, which often result in painful and debilitating skeletal-related events. Inhibitors of bone resorption, such as bisphosphonates and denosumab...

    Authors: Jean-Jacques Body, Roger von Moos, Daniela Niepel and Bertrand Tombal

    Citation: BMC Urology 2018 18:81

    Content type: Review

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  28. Elderly people are representative for the patients most likely to be treated with anticholinergics for overactive bladder (OAB). They often receive further drugs with anticholinergic properties for concomitant...

    Authors: A. Ivchenko, R.-H. Bödeker, C. Neumeister and A. Wiedemann

    Citation: BMC Urology 2018 18:80

    Content type: Research article

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  29. BRAF-activated long non-coding RNA (BANCR) has been associated with various types of cancer. Nevertheless, the role of BANCR in clear cell renal cell carcinoma (ccRCC) is still not fully understood. This study...

    Authors: Sheng Xue, Sheng-Qun Jiang, Qing-wen Li, Sheng Wang, Jian Li, Shuai Yang, Hai-Min Zhang, Yun-Fei Xu, Long-Sheng Wang and Jun-Hua Zheng

    Citation: BMC Urology 2018 18:79

    Content type: Research article

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  30. Refinement of parameters defining prostate cancer (PC) prognosis are urgently needed to identify patients with indolent versus aggressive disease. The Canadian Prostate Cancer Biomaker Network (CPCBN) consists...

    Authors: Véronique Ouellet, Armen Aprikian, Alain Bergeron, Fadi Brimo, Robert G. Bristow, Simone Chevalier, Darrel Drachenberg, Ladan Fazli, Neil E. Fleshner, Martin Gleave, Pierre Karakiewicz, Laurence Klotz, Louis Lacombe, Jean-Baptiste Lattouf, Theodorus van der Kwast, Jeremy A. Squire…

    Citation: BMC Urology 2018 18:78

    Content type: Research article

    Published on:

  31. This analysis estimated the number needed to treat with enzalutamide versus bicalutamide to achieve one additional patient with chemotherapy-naïve metastatic castration-resistant prostate cancer who would obta...

    Authors: Neil M. Schultz, Neal D. Shore, Simon Chowdhury, Laurence H. Klotz, Raoul S. Concepcion, David F. Penson, Lawrence I. Karsh, Hongbo Yang, Bruce A. Brown, Arie Barlev and Scott C. Flanders

    Citation: BMC Urology 2018 18:77

    Content type: Research article

    Published on:

    The Correction to this article has been published in BMC Urology 2018 18:84

  32. Persistence on-treatment with antimuscarinics in patients with overactive bladder (OAB) is reported to be sub-optimal. This retrospective, longitudinal, observational cohort study assessed treatment persistenc...

    Authors: Jameel Nazir, Zalmai Hakimi, Florent Guelfucci, Amine Khemiri, Francis Fatoye, Ana María Mora Blázquez and Marta Hernández González

    Citation: BMC Urology 2018 18:76

    Content type: Research article

    Published on:

  33. To study the expression pattern, localisation and potential clinical significance of aquaporin water channels (AQP) both in prostate cancer (PC) cell lines and in benign and malignant human prostate tissue.

    Authors: Johannes Bründl, Sabine Wallinger, Johannes Breyer, Florian Weber, Matthias Evert, Nikolaos Theodoros Georgopoulos, Bernd Rosenhammer, Maximilian Burger, Wolfgang Otto and Peter Rubenwolf

    Citation: BMC Urology 2018 18:75

    Content type: Research article

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  34. We present a rare case where distant metastasis of a low grade bladder tumor was observed. We carried out detailed genomic analysis and cell based experiments on patient tumor samples to study tumor evolution,...

    Authors: Marvin J. Van Every, Garrett Dancik, Venki Paramesh, Grzegorz T. Gurda, David R. Meier, Steven E. Cash, Craig S. Richmond and Sunny Guin

    Citation: BMC Urology 2018 18:74

    Content type: Case report

    Published on:

  35. To explore the feasibility and long-term outcomes of renal preservation in a retrospective cohort of patients with ureteral urothelial carcinoma undergoing total ureterectomy with ileal-ureteral substitution.

    Authors: Yin-Chien Ou, Che-Yuan Hu, Hong-Lin Cheng and Wen-Horng Yang

    Citation: BMC Urology 2018 18:73

    Content type: Research article

    Published on:

  36. Neurogenic bladder (NGB) dysfunction after spinal cord injury (SCI) is generally irreversible. Preliminary animal and human studies have suggested that initiation of sacral neuromodulation (SNM) immediately fo...

    Authors: Jeffrey D. Redshaw, Sara M. Lenherr, Sean P. Elliott, John T. Stoffel, Jeffrey P. Rosenbluth, Angela P. Presson and Jeremy B. Myers

    Citation: BMC Urology 2018 18:72

    Content type: Study protocol

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  37. Our understanding of effective perioperative supportive interventions for patients undergoing cystectomy procedures and how these may affect short and long-term health outcomes is limited.

    Authors: Helen Quirk, Derek J. Rosario and Liam Bourke

    Citation: BMC Urology 2018 18:71

    Content type: Research article

    Published on:

  39. The benefits of PSA-based screening for prostate cancer (PCa) are controversial. The Canadian and American Task Forces on Preventive Health Care (CTFPHC & USPSTF) have released recommendations against the use ...

    Authors: Ahmed S. Zakaria, Alice Dragomir, Fadi Brimo, Wassim Kassouf, Simon Tanguay and Armen Aprikian

    Citation: BMC Urology 2018 18:69

    Content type: Research article

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  40. Recent studies suggest that FGFR3 is a potential therapeutic target in urothelial carcinoma (UC). The purpose of this study was to evaluate the rates and types of FGFR3 aberrations in patients with muscle-invasiv...

    Authors: Young Saing Kim, Kyung Kim, Ghee-Young Kwon, Su Jin Lee and Se Hoon Park

    Citation: BMC Urology 2018 18:68

    Content type: Research article

    Published on:

  41. Aspergillosis in patients with impaired immunity usually presents with invasive pulmonary infection and dissemination to a variety of organs via hematogenous spread. Aspergilloma in the retroperitoneal cavity ...

    Authors: Risa Shinoki, Teppei Takeshima, Koichiro Horie, Toshihiro Matsui, Ayako Horita, Ikuo Saito and Kotaro Hirai

    Citation: BMC Urology 2018 18:67

    Content type: Case report

    Published on:

  42. New biologic therapies directly injected into the prostate are in clinical trials for prostatic diseases. There is a need to understand distribution of injected therapies as a function of prostatic anatomy, ph...

    Authors: Martin L. Brady, King Scott Coffield, Thomas J. Kuehl, Raghu Raghavan, V. O. Speights Jr, Belur Patel, Scott Wilson, Mike Wilson and Rick M. Odland

    Citation: BMC Urology 2018 18:66

    Content type: Research article

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  43. Reduced clinical exposure to urology at the undergraduate or internship level is the main explanation for the marked decrease in applicants to urology residencies. This manuscript was to access the application...

    Authors: Hwa Yeon Sun, Young Myoung Ko, Seung Wook Lee, Bora Lee and Jae Heon Kim

    Citation: BMC Urology 2018 18:65

    Content type: Research article

    Published on:

  45. To provide indicators for the likelihood of sperm retrieval in patients undergoing testicular sperm extraction is a major issue in the management of male infertility by TESE. The aim of our study was to determ...

    Authors: Lucio Gnessi, Filomena Scarselli, Maria Giulia Minasi, Stefania Mariani, Carla Lubrano, Sabrina Basciani, Pier Francesco Greco, Mikiko Watanabe, Giorgio Franco, Alessio Farcomeni and Ermanno Greco

    Citation: BMC Urology 2018 18:63

    Content type: Research article

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  46. Even though evidence based medicine, guidelines and algorithms still represent the pillars of the management of chronic diseases (i.e: hypertension, diabetes mellitus), a patient centred approach has been rece...

    Authors: Cosimo De Nunzio, Fabrizio Presicce, Riccardo Lombardo, Alberto Trucchi, Mariangela Bellangino, Andrea Tubaro and Egidio Moja

    Citation: BMC Urology 2018 18:62

    Content type: Research article

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  47. Αim of the study was to determine the effect of mirabegron, used for overactive bladder (OAB) treatment, on female sexual function.

    Authors: A. Zachariou, C. Mamoulakis, M. Filiponi, F. Dimitriadis, J. Giannakis, S. Skouros, P. Tsounapi, A. Takenaka and N. Sofikitis

    Citation: BMC Urology 2018 18:61

    Content type: Research article

    Published on:

  48. The preoperative neutrophil-to-lymphocyte ratio (NLR), C-reactive protein/albumin ratio (CRP/Alb ratio) and platelet-to-lymphocyte ratio (PLR) have been demonstrated to predict the clinical outcome of various ...

    Authors: Sezim Agizamhan, Feng Qu, Ning Liu, Jing Sun, Wei Xu, Lihua Zhang, Hongqian Guo and Weidong Gan

    Citation: BMC Urology 2018 18:60

    Content type: Research article

    Published on:

  49. Epidermal growth factor receptor (EGFR) has been shown to have abnormal expression in many human cancers and is considered as a marker of poor prognosis. Frequency of over expression in bladder cancer has not ...

    Authors: Atif Ali hashmi, Zubaida Fida Hussain, Muhammad Irfan, Erum Yousuf Khan, Naveen Faridi, Hanna Naqvi, Amir Khan and Muhammad Muzzammil Edhi

    Citation: BMC Urology 2018 18:59

    Content type: Research article

    Published on:

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