Articles

The EEF1A2 gene expression as risk predictor in localized prostate cancer

Besides clinical stage and Gleason score, risk-stratification of prostate cancer in the pretherapeutic setting mainly relies on the serum PSA level. Yet, this is associated with many uncertainties. With regard...

Authors: Thomas Stefan Worst, Frank Waldbillig, Abdallah Abdelhadi, Cleo-Aron Weis, Maria Gottschalt, Annette Steidler, Jost von Hardenberg, Maurice Stephan Michel and Philipp Erben

A low psoas muscle volume correlates with a longer hospitalization after radical cystectomy

Recently, sarcopenia has been reported as a new predictor for patient outcomes or likelihood of post-operative complications. The purpose of this study was to evaluate the association of the psoas muscle volum...

Authors: Yoko Saitoh-Maeda, Takashi Kawahara, Yasuhide Miyoshi, Sohgo Tsutsumi, Daiji Takamoto, Kota Shimokihara, Yuutaro Hayashi, Taku Mochizuki, Mari Ohtaka, Manami Nakamura, Yusuke Hattori, Jun-ichi Teranishi, Yasushi Yumura, Kimito Osaka, Hiroki Ito, Kazuhide Makiyama…

Increasing bladder capacity by foot stimulation in rats with spinal cord injuries

This study was to explore the possibility that foot stimulation increased bladder capacity(BC) in rats with neurogenic bladder secondary to T10 spinal cord injuries.

Authors: Guoqing Chen, Limin Liao, Zhaoxia Wang, Xing Li and Wenjuan Du

Should manual detorsion be a routine part of treatment in testicular torsion?

It was aimed to investigate the efficiency and reliability of the manual detorsion (MD) procedure in patients diagnosed with testicular torsion (TT).

Authors: Arif Demirbas, Demirhan Orsan Demir, Erim Ersoy, Mucahit Kabar, Serkan Ozcan, Mehmet Ali Karagoz, Ozgecan Demirbas and Omer Gokhan Doluoglu

Resource utilization and costs associated with the addition of an antimuscarinic in patients treated with an alpha-blocker for the treatment of urinary symptoms linked to benign prostatic hyperplasia

There has been a change in the focus of attention from prostate to bladder, as the etiology of lower urinary tract symptoms (LUTS) makes the bladder an additional therapeutic target. This study aims to evaluat...

Authors: Antoni Sicras-Mainar, Ruth Navarro-Artieda, Ana Mª. Mora and Marta Hernández

Application and analysis of retroperitoneal laparoscopic partial nephrectomy with sequential segmental renal artery clamping for patients with multiple renal tumor: initial experience

To explore the feasibility and safety of retroperitoneal laparoscopic partial nephrectomy with sequential segmental renal artery clamping for the patients with multiple renal tumor of who have solitary kidney ...

Authors: Jundong Zhu, Fan Jiang, Pu Li, Pengfei Shao, Chao Liang, Aiming Xu, Chenkui Miao, Chao Qin, Zengjun Wang and Changjun Yin

Transperineal cryotherapy for unresectable muscle invasive bladder cancer: preliminary experience with 7 male patients

Radical cystectomy (RC) with pelvic lymph node dissection (PLND) and urinary diversion (UD) is considered the standard treatment for muscle invasive bladder cancer (MIBC). In a part of patients, RC procedure i...

Authors: Qing Zhang, Shiwei Zhang, Shun Zhang, Wei Wang, Xiaozhi Zhao, Yongming Deng, Huibo Lian and Hongqian Guo

Can Randall’s plug composed of calcium oxalate form via the free particle mechanism?

The likelihood of a Randall’s plug composed of calcium oxalate monohydrate (COM) forming by the free particle mechanism in a model of kidney with a structure recently described by Robertson was examined at the...

Authors: F. Grases and O. Söhnel

Comparison of radiofrequency ablation and partial nephrectomy for tumor in a solitary kidney

To estimate oncologic and functional outcomes for radiofrequency ablation (RFA) versus partial nephrectomy (PN) for tumors in a solitary kidney.

Authors: Wu Xiaobing, Gong Wentao, Liu Guangxiang, Zhang Fan, Gan Weidong, Guo Hongqian and Zhang Gutian

Extranodal nasal-type natural killer/T-cell lymphoma with penile involvement: a case report and review of the literature

Extranodal natural killer/T-cell lymphoma (ENKTL) usually presents as a localized disease in the nasal cavity; extension to the male genitourinary system is very rare and has been characterized only recently. ...

Authors: Xiaotian Wang, Zimu Gong, Shawn Xiang Li, Wei Yan and Yongsheng Song

Prophylactic antibiotic use in pediatric patients undergoing urinary tract catheterization: a survey of members of the Society for Pediatric Urology

Current organizational guidelines regarding use of antibiotics during urinary tract catheterization are based on limited evidence and are not directly applicable to the pediatric urology population. We seek to...

Authors: Alexander P. Glaser, Ilina Rosoklija, Emilie K. Johnson and Elizabeth B. Yerkes

Assembling and validating data from multiple sources to study care for Veterans with bladder cancer

Despite the high prevalence of bladder cancer, research on optimal bladder cancer care is limited. One way to advance observational research on care is to use linked data from multiple sources. Such big data r...

Authors: Florian R. Schroeck, Brenda Sirovich, John D. Seigne, Douglas J. Robertson and Philip P. Goodney

Predictive value of C-reactive protein in patients treated with sunitinib for metastatic clear cell renal cell carcinoma

Sunitinib has become mainstay first line treatment for patients with metastatic renal clear cell carcinoma (mRCC). Still, useful predictive markers of response are lacking and urgently needed for clinical deci...

Authors: Martin Pilskog, Christian Beisland, Lars A. Akslen, Leif Bostad, Åse Haug, Daniel Heinrich, Karin M. Hjelle and Oddbjørn Straume

Management of large renal stones: laparoscopic pyelolithotomy versus percutaneous nephrolithotomy

Percutaneous nephrolithotomy (PCNL) remains the standard procedure for large (≥2 cm) renal calculi; however, laparoscopic pyelolithotomy (LPL) can be used as an alternative management procedure. The aim of pre...

Authors: Yunjin Bai, Yin Tang, Lan Deng, Xiaoming Wang, Yubo Yang, Jia Wang and Ping Han

Evaluation of noise hazard during the holmium laser enucleation of prostate

To evaluate noise hazard during holmium laser enucleation of the prostate (HoLEP), we designed a study to detect such a risk in this procedure.

Authors: Huan Xu, Yan-bo Chen, Meng Gu, Qi Chen and Zhong Wang

Presence of transient hydronephrosis immediately after surgery has a limited influence on renal function 1 year after ileal neobladder construction

Urinary tract obstruction and postoperative hydronephrosis are risk factor for renal function deterioration after orthotopic ileal neobladder construction. However, reports of relationship between transient hy...

Authors: Takuma Narita, Shingo Hatakeyama, Takuya Koie, Shogo Hosogoe, Teppei Matsumoto, Osamu Soma, Hayato Yamamoto, Tohru Yoneyama, Yuki Tobisawa, Takahiro Yoneyama, Yasuhiro Hashimoto and Chikara Ohyama

Retroperitoneal laparoscopic partial nephrectomy with segmental renal artery clamping for cancer of the left upper calyx: a case report

Currently, the standard treatment for renal pelvis carcinoma is radical nephroureterectomy with bladder cuff excision. To describe the feasibility of retroperitoneal laparoscopic partial nephrectomy with segme...

Authors: Yajie Yu, Chao Liang, Meiling Bao, Pengfei Shao and Zengjun Wang

A modified neo-vagina procedure in a low resource urogynecological unit: a case report of a 21 year old with Mayer-Rokitansky-Küster-Hauser (mrkh) Syndrome operated at Mbarara referral hospital, Southwestern Uganda

Although vaginal agenesis as may occur in Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome is a rare condition, it is associated with not only anatomical problems but also serious psychological and social proble...

Authors: Musa Kayondo, Joseph Njagi, Peter Kivuniike Mukasa and Tom Margolis

A gonadotropin-releasing hormone antagonist reduces serum adrenal androgen levels in prostate cancer patients

Adrenal androgens play an important role in the development of castration-resistant prostate cancer therapeutics. The effect of gonadotropin-releasing hormone (GnRH) antagonists on adrenal androgens has not be...

Authors: Yoshiyuki Miyazawa, Yoshitaka Sekine, Takahiro Syuto, Masashi Nomura, Hidekazu Koike, Hiroshi Matsui, Yasuhiro Shibata, Kazuto Ito and Kazuhiro Suzuki

Erratum to: Expression and function of phosphodiesterases (PDEs) in the rat urinary bladder

Authors: Xiaofei Zhu, Kui Zhai, Yue Mi and Guangju Ji

The application of a novel integrated rigid and flexible Nephroscope in percutaneous nephrolithotomy for renal staghorn stones

Renal staghorn stones are challenging for urologists to ensure maximum stone clearance and minimal morbidity. Percutaneous nephrolithotomy (PCNL) has become the gold standard treatment for renal staghorn stone...

Authors: Huan Yang, Jianxing Li, Gang Long and Shaogang Wang

Infrarenal high intra-abdominal testis: fusion of T2-weighted and diffusion-weighted magnetic resonance images and pathological findings

Several recent reports have demonstrated that the preoperative sensitivity and accuracy of identifying and locating non-palpable testes increases with the use of conventional MRI, in addition to diffusion-weig...

Authors: Seiji Hoshi, Yuichi Sato, Junya Hata, Hidenori Akaihata, Soichiro Ogawa, Nobuhiro Haga and Yoshiyuki Kojima

Symptom clusters and related factors in bladder cancer patients three months after radical cystectomy

To identify symptom distress and clusters in patients 3 months after radical cystectomy and to explore their potential predictors.

Authors: Hongyan Ren, Ping Tang, Qinghua Zhao and Guosheng Ren

Alpha_1A-adrenoceptor antagonist improves underactive bladder associated with diabetic cystopathy via bladder blood flow in rats

Patients with diabetes experience lower urinary tract symptoms. Cystopathy may evolve into underactive bladder (UAB), depending on the degree and duration of the symptoms. In the present study, we aimed to inv...

Authors: Saori Yonekubo, Satoshi Tatemichi, Kazuyasu Maruyama and Mamoru Kobayashi

A retrospective feasibility study of biweekly, reduced-dose docetaxel in Asian patients with castrate-resistant, metastatic prostate cancer

The aim of this retrospective study was to evaluate the clinical outcomes of reduced dose, biweekly docetaxel chemotherapy for Korean patients with castrate-resistant prostate cancer (CRPC).

Authors: Hae Su Kim, Ji Yun Lee, Su Jin Lee, Ho Yeong Lim, Hyun Hwan Sung, Hwang Gyun Jeon, Byong Chang Jeong, Seong Il Seo, Seong Soo Jeon, Hyun Moo Lee, Han-Yong Choi and Se Hoon Park

Assessment of lower urinary symptom flare with overactive bladder symptom score and International Prostate Symptom Score in patients treated with iodine-125 implant brachytherapy: long-term follow-up experience at a single institute

The aim of this study was to evaluate the combined use of the overactive bladder symptom score (OABSS) and International Prostate Symptom Score (IPSS) as an assessment tool for urinary symptom flare after iodi...

Authors: Makito Miyake, Nobumichi Tanaka, Isao Asakawa, Shunta Hori, Yosuke Morizawa, Yoshihiro Tatsumi, Yasushi Nakai, Takeshi Inoue, Satoshi Anai, Kazumasa Torimoto, Katsuya Aoki, Masatoshi Hasegawa, Tomomi Fujii, Noboru Konishi and Kiyohide Fujimoto

Simultaneous antegrade and retrograde endoscopic treatment of non-malignant ureterointestinal anastomotic strictures following urinary diversion

The ureterointestinal anastomosis stricture (UAS) is a common complication of urinary diversion after radical cystectomy. For decades, open anastomotic revision remained the gold standard for the treatment of ...

Authors: Weiguo Hu, Boxing Su, Bo Xiao, Xin Zhang, Song Chen, Yuzhe Tang, Yubao Liu, Meng Fu and Jianxing Li

Heterogeneity in high-risk prostate cancer treated with high-dose radiation therapy and androgen deprivation therapy

Our aim was to assess the heterogeneity of high-risk (HR) prostate cancer managed with high-dose external beam radiotherapy (EBRT) with androgen deprivation therapy (ADT).

Authors: Daniel N. Cagney, Mary Dunne, Carmel O’Shea, Marie Finn, Emma Noone, Martina Sheehan, Lesley McDonagh, Lydia O’Sullivan, Pierre Thirion and John Armstrong

Efficacy of commercialised extracorporeal shock wave lithotripsy service: a review of 589 renal stones

Extracorporeal shockwave lithotripsy (ESWL) is the management of choice for renal stones 20 mm or smaller, with a stone clearance rate of up to 89%. The purpose of the present is to investigate the efficacy of...

Authors: Tommy Kjærgaard Nielsen and Jørgen Bjerggaard Jensen

Transcutaneous electrical stimulation of somatic afferent nerves in the foot relieved symptoms related to postoperative bladder spasms

Bladder spasm is a common side effect of urological surgery. Main treatment modalities include opioids or anticholinergic medication; however, bladder spasms still occur even after these interventions. Recent ...

Authors: Chanjuan Zhang, Zhiying Xiao, Xiulin Zhang, Liqiang Guo, Wendong Sun, Changfeng Tai, Zhaoqun Jiang and Yuqiang Liu

The influence of prior laparoscopic experience on learning laparoendoscopic single site surgery: a prospective comparative preliminary study using cystorraphy in a live porcine model

The purpose of this study is to assess the impact of prior laparoscopic experience on the ability to learn laparoendoscopic single site surgery (LESS) skills.

Authors: U-Syn Ha, Kyu Won Lee, Sun Wook Kim, Seung Hyun Jeon, Tae Gyun Kwon, Hyung Keun Park and Sung-Hoo Hong

Patient driven care in the management of prostate cancer: analysis of the United States military healthcare system

Patient preferences are assumed to impact healthcare resource utilization, especially treatment options. There is limited data exploring this phenomenon. We sought to identify factors associated with patients ...

Authors: Muhammad Ali Chaudhary, Jeffrey J. Leow, Matthew Mossanen, Ritam Chowdhury, Wei Jiang, Peter A. Learn, Joel S. Weissman and Steven L. Chang

Polypoid arteriovenous malformation of the ureter mimicking a fibroepithelial polyp, a case report

Arteriovenous malformations (AVM) of the urinary tract are extremely rare. To the best of our knowledge, only three case of AVM of the ureter have been described in the literature so far.

Authors: C.S. ten Donkelaar, A.C. Houwert, F.J.W. ten Kate and M.T.W.T. Lock

Expression and function of phosphodiesterases (PDEs) in the rat urinary bladder

It has been shown that hosphodiesterases (PDEs) play an important role in mediating the smooth muscle tone of rat urinary bladder. However, the gene expression profiles of them were still unknown.

Authors: Xiaofei Zhu, Kui Zhai, Yue Mi and Guangju Ji

Assessment of free-hand transperineal targeted prostate biopsy using multiparametric magnetic resonance imaging-transrectal ultrasound fusion in Chinese men with prior negative biopsy and elevated prostate-specific antigen

To evaluate the role of free-hand transperineal targeted prostate biopsy using multiparametric magnetic resonance imaging-transrectal ultrasound (mpMRI-TRUS) fusion in Chinese men with repeated biopsy.

Authors: Huibo Lian, Junlong Zhuang, Wei Wang, Bing Zhang, Jiong Shi, Danyan Li, Yao Fu, Xuping Jiang, Weimin Zhou and Hongqian Guo

Transperineal ultrasound-guided prostate biopsy is safe even when patients are on combination antiplatelet and/or anticoagulation therapy

To assess whether hemorrhagic complications associated with transperineal prostate biopsy increased in patients on antiplatelet and/or anticoagulant therapy.

Authors: Kimitoshi Saito, Satoshi Washino, Yuhki Nakamura, Tsuzumi Konishi, Masashi Ohshima, Yoshiaki Arai and Tomoaki Miyagawa

Impact of a protein-based assay that predicts prostate cancer aggressiveness on urologists’ recommendations for active treatment or active surveillance: a randomized clinical utility trial

Of the more than 1.1 million men diagnosed worldwide annually with prostate cancer, the majority have indolent tumors. Distinguishing between aggressive and indolent cancer is an important clinical challenge. ...

Authors: John W. Peabody, Lisa M. DeMaria, Diana Tamondong-Lachica, Jhiedon Florentino, M. Czarina Acelajado, Othman Ouenes, Jerome P. Richie and Trever Burgon

Comparison of the efficacy and safety of URSL, RPLU, and MPCNL for treatment of large upper impacted ureteral stones: a randomized controlled trial

There are three minimally invasive methods for the management of large upper impacted ureteral stones: mini-percutaneous nephrolithotomy (MPCNL), transurethral ureteroscope lithotripsy (URSL), and retroperiton...

Authors: Yunyan Wang, Bing Zhong, Xiaosong Yang, Gongcheng Wang, Peijin Hou and Junsong Meng

The neutrophil-to-lymphocyte ratio (NLR) predicts adrenocortical carcinoma and is correlated with the prognosis

The neutrophil-to-lymphocyte ratio (NLR) is reported as a biomarker for some solid malignant diseases. Thus far, however, no reports of the relationship between the NLR and adrenal tumors have been published. ...

Authors: Taku Mochizuki, Takashi Kawahara, Daiji Takamoto, Kazuhide Makiyama, Yusuke Hattori, Jun-ichi Teranishi, Yasuhide Miyoshi, Yasushi Yumura, Masahiro Yao and Hiroji Uemura

Intraoperative and postoperative feasibility and safety of total tubeless, tubeless, small-bore tube, and standard percutaneous nephrolithotomy: a systematic review and network meta-analysis of 16 randomized controlled trials

Percutaneous nephrolithotomy (PCNL) is performed to treat relatively large renal stones. Recent publications indicate that tubeless and total tubeless (stentless) PCNL is safe in selected patients. We performe...

Authors: Joo Yong Lee, Seong Uk Jeh, Man Deuk Kim, Dong Hyuk Kang, Jong Kyou Kwon, Won Sik Ham, Young Deuk Choi and Kang Su Cho

Performance characteristics of prostate-specific antigen density and biopsy core details to predict oncological outcome in patients with intermediate to high-risk prostate cancer underwent robot-assisted radical prostatectomy

Many urologic surgeons refer to biopsy core details for decision making in cases of localized prostate cancer (PCa) to determine whether an extended resection and/or lymph node dissection should be performed. ...

Authors: Masahiro Yashi, Akinori Nukui, Yuumi Tokura, Kohei Takei, Issei Suzuki, Kazumasa Sakamoto, Hideo Yuki, Tsunehito Kambara, Hironori Betsunoh, Hideyuki Abe, Yoshitatsu Fukabori, Yoshimasa Nakazato, Yasushi Kaji and Takao Kamai

Assessing health-related quality of life in urology – a survey of 4500 German urologists

Urological diseases and their treatment may negatively influence continence, potency, and health-related quality of life (HRQOL). Although current guidelines recommend HRQOL assessment in clinical urology, spe...

Authors: A. Schmick, M. Juergensen, V. Rohde, A. Katalinic and A. Waldmann

Life after prostate cancer treatment: a mixed methods study of the experiences of men with sexual dysfunction and their partners

Prostate cancer is the most common non-skin cancer in men and sexual dysfunction is the most frequently reported long-term side effect of prostate cancer surgery or radiation. The aim of this study was to exam...

Authors: Jeffrey A. Albaugh, Nat Sufrin, Brittany R. Lapin, Jacqueline Petkewicz and Sandi Tenfelde

The usefulness of flexible cystoscopy for preventing double-J stent malposition after laparoscopic ureterolithotomy

The aim of this study was to evaluate the role of flexible cystoscopy in preventing malpositioning of the ureteral stent after laparoscopic ureterolithotomy in male patients.

Authors: Jae-Yoon Kim, Seok-Ho Kang, Jun Cheon, Jeong-Gu Lee, Je-Jong Kim and Sung-Gu Kang

Intravenous misplacement of the nephrostomy catheter following percutaneous nephrostolithotomy: two case reports and literature review

Intravenous misplacement of a nephrostomy tube after percutaneous nephrostolithotomy (PCNL) is very rare in clinical experiences. This report summarizes the characteristics and management of intravenous mispla...

Authors: Weijin Fu, Zhanbin Yang, Zhibin Xie and Haibiao Yan

Toileting behaviors and overactive bladder in patients with type 2 diabetes: a cross-sectional study in China

Overactive bladder is more prevalent in patients with type 2 diabetes than in those without diabetes. Unhealthy toileting behaviors may be associated with the development and worsening of overactive bladder sy...

Authors: Dongjuan Xu, Ran Cheng, Aixia Ma, Meng Zhao and Kefang Wang

When to perform bone scintigraphy in patients with newly diagnosed prostate cancer? a retrospective study

To determine when a bone scintigraphy investigation is appropriate in patients with newly diagnosed prostate cancer (PCa).

Authors: Yiwei Lin, Qiqi Mao, Bin Chen, Liujiang Wang, Ben Liu, Xiangyi Zheng and Liping Xie

Jack stone in the bladder: case report of a rare entity

Jackstone is a bladder stone that has a similar appearance to toy jacks. However review of the English language medical literature revealed only a few previous reports of jackstone calculus.

Authors: Duminda Subasinghe, Serozsha Goonewardena and Vickneswaran Kathiragamathamby

Predictors of survival outcomes in native sub Saharan black men newly diagnosed with metastatic prostate cancer

Though it is well established that black men are at higher risk of prostate cancer (PCa) very little is known about the disease in native sub Saharan black men. Newly diagnosed metastatic PCa patients treated ...

Authors: Jibril Oyekunle Bello

Anti-proliferative potential of Glucosamine in renal cancer cells via inducing cell cycle arrest at G0/G1 phase

Renal cell carcinoma (RCC) is one of the most common types of cancer in urological system worldwide. Recently, the anticancer role of Glucosamine has been studied in many types of cancer. The aim of this study...

Authors: Long-sheng Wang, Shao-jun Chen, Jun-feng Zhang, Meng-nan Liu, Jun-hua Zheng and Xu-dong Yao