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  2. Immediate early response gene 3 (IER3) is a stress-inducible gene, which exerts diverse effects in regulating cell apoptosis and cell cycle. Growing evidence shows that IER3 functions either as an oncogene or ...

    Authors: Jianheng Ye, Yanqiong Zhang, Zhiduan Cai, Minyao Jiang, Bowei Li, Guo Chen, Yanru Zeng, Yuxiang Liang, Shulin Wu, Zongwei Wang, Huichan He, Weide Zhong and Chin-Lee Wu

    Citation: BMC Urology 2018 18:82

    Content type: Research article

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  3. Most patients with advanced prostate cancer develop bone metastases, which often result in painful and debilitating skeletal-related events. Inhibitors of bone resorption, such as bisphosphonates and denosumab...

    Authors: Jean-Jacques Body, Roger von Moos, Daniela Niepel and Bertrand Tombal

    Citation: BMC Urology 2018 18:81

    Content type: Review

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  4. Elderly people are representative for the patients most likely to be treated with anticholinergics for overactive bladder (OAB). They often receive further drugs with anticholinergic properties for concomitant...

    Authors: A. Ivchenko, R.-H. Bödeker, C. Neumeister and A. Wiedemann

    Citation: BMC Urology 2018 18:80

    Content type: Research article

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  5. BRAF-activated long non-coding RNA (BANCR) has been associated with various types of cancer. Nevertheless, the role of BANCR in clear cell renal cell carcinoma (ccRCC) is still not fully understood. This study...

    Authors: Sheng Xue, Sheng-Qun Jiang, Qing-wen Li, Sheng Wang, Jian Li, Shuai Yang, Hai-Min Zhang, Yun-Fei Xu, Long-Sheng Wang and Jun-Hua Zheng

    Citation: BMC Urology 2018 18:79

    Content type: Research article

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  6. Refinement of parameters defining prostate cancer (PC) prognosis are urgently needed to identify patients with indolent versus aggressive disease. The Canadian Prostate Cancer Biomaker Network (CPCBN) consists...

    Authors: VĂ©ronique Ouellet, Armen Aprikian, Alain Bergeron, Fadi Brimo, Robert G. Bristow, Simone Chevalier, Darrel Drachenberg, Ladan Fazli, Neil E. Fleshner, Martin Gleave, Pierre Karakiewicz, Laurence Klotz, Louis Lacombe, Jean-Baptiste Lattouf, Theodorus van der Kwast, Jeremy A. Squire…

    Citation: BMC Urology 2018 18:78

    Content type: Research article

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  7. This analysis estimated the number needed to treat with enzalutamide versus bicalutamide to achieve one additional patient with chemotherapy-naĂŻve metastatic castration-resistant prostate cancer who would obta...

    Authors: Neil M. Schultz, Neal D. Shore, Simon Chowdhury, Laurence H. Klotz, Raoul S. Concepcion, David F. Penson, Lawrence I. Karsh, Hongbo Yang, Bruce A. Brown, Arie Barlev and Scott C. Flanders

    Citation: BMC Urology 2018 18:77

    Content type: Research article

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    The Correction to this article has been published in BMC Urology 2018 18:84

  8. Persistence on-treatment with antimuscarinics in patients with overactive bladder (OAB) is reported to be sub-optimal. This retrospective, longitudinal, observational cohort study assessed treatment persistenc...

    Authors: Jameel Nazir, Zalmai Hakimi, Florent Guelfucci, Amine Khemiri, Francis Fatoye, Ana María Mora Blázquez and Marta Hernández González

    Citation: BMC Urology 2018 18:76

    Content type: Research article

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  9. To study the expression pattern, localisation and potential clinical significance of aquaporin water channels (AQP) both in prostate cancer (PC) cell lines and in benign and malignant human prostate tissue.

    Authors: Johannes BrĂĽndl, Sabine Wallinger, Johannes Breyer, Florian Weber, Matthias Evert, Nikolaos Theodoros Georgopoulos, Bernd Rosenhammer, Maximilian Burger, Wolfgang Otto and Peter Rubenwolf

    Citation: BMC Urology 2018 18:75

    Content type: Research article

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  10. We present a rare case where distant metastasis of a low grade bladder tumor was observed. We carried out detailed genomic analysis and cell based experiments on patient tumor samples to study tumor evolution,...

    Authors: Marvin J. Van Every, Garrett Dancik, Venki Paramesh, Grzegorz T. Gurda, David R. Meier, Steven E. Cash, Craig S. Richmond and Sunny Guin

    Citation: BMC Urology 2018 18:74

    Content type: Case report

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  11. To explore the feasibility and long-term outcomes of renal preservation in a retrospective cohort of patients with ureteral urothelial carcinoma undergoing total ureterectomy with ileal-ureteral substitution.

    Authors: Yin-Chien Ou, Che-Yuan Hu, Hong-Lin Cheng and Wen-Horng Yang

    Citation: BMC Urology 2018 18:73

    Content type: Research article

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  12. Neurogenic bladder (NGB) dysfunction after spinal cord injury (SCI) is generally irreversible. Preliminary animal and human studies have suggested that initiation of sacral neuromodulation (SNM) immediately fo...

    Authors: Jeffrey D. Redshaw, Sara M. Lenherr, Sean P. Elliott, John T. Stoffel, Jeffrey P. Rosenbluth, Angela P. Presson and Jeremy B. Myers

    Citation: BMC Urology 2018 18:72

    Content type: Study protocol

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  13. Our understanding of effective perioperative supportive interventions for patients undergoing cystectomy procedures and how these may affect short and long-term health outcomes is limited.

    Authors: Helen Quirk, Derek J. Rosario and Liam Bourke

    Citation: BMC Urology 2018 18:71

    Content type: Research article

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  15. The benefits of PSA-based screening for prostate cancer (PCa) are controversial. The Canadian and American Task Forces on Preventive Health Care (CTFPHC & USPSTF) have released recommendations against the use ...

    Authors: Ahmed S. Zakaria, Alice Dragomir, Fadi Brimo, Wassim Kassouf, Simon Tanguay and Armen Aprikian

    Citation: BMC Urology 2018 18:69

    Content type: Research article

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  16. Recent studies suggest that FGFR3 is a potential therapeutic target in urothelial carcinoma (UC). The purpose of this study was to evaluate the rates and types of FGFR3 aberrations in patients with muscle-invasiv...

    Authors: Young Saing Kim, Kyung Kim, Ghee-Young Kwon, Su Jin Lee and Se Hoon Park

    Citation: BMC Urology 2018 18:68

    Content type: Research article

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  17. Aspergillosis in patients with impaired immunity usually presents with invasive pulmonary infection and dissemination to a variety of organs via hematogenous spread. Aspergilloma in the retroperitoneal cavity ...

    Authors: Risa Shinoki, Teppei Takeshima, Koichiro Horie, Toshihiro Matsui, Ayako Horita, Ikuo Saito and Kotaro Hirai

    Citation: BMC Urology 2018 18:67

    Content type: Case report

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  18. New biologic therapies directly injected into the prostate are in clinical trials for prostatic diseases. There is a need to understand distribution of injected therapies as a function of prostatic anatomy, ph...

    Authors: Martin L. Brady, King Scott Coffield, Thomas J. Kuehl, Raghu Raghavan, V. O. Speights Jr, Belur Patel, Scott Wilson, Mike Wilson and Rick M. Odland

    Citation: BMC Urology 2018 18:66

    Content type: Research article

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  19. Reduced clinical exposure to urology at the undergraduate or internship level is the main explanation for the marked decrease in applicants to urology residencies. This manuscript was to access the application...

    Authors: Hwa Yeon Sun, Young Myoung Ko, Seung Wook Lee, Bora Lee and Jae Heon Kim

    Citation: BMC Urology 2018 18:65

    Content type: Research article

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  21. To provide indicators for the likelihood of sperm retrieval in patients undergoing testicular sperm extraction is a major issue in the management of male infertility by TESE. The aim of our study was to determ...

    Authors: Lucio Gnessi, Filomena Scarselli, Maria Giulia Minasi, Stefania Mariani, Carla Lubrano, Sabrina Basciani, Pier Francesco Greco, Mikiko Watanabe, Giorgio Franco, Alessio Farcomeni and Ermanno Greco

    Citation: BMC Urology 2018 18:63

    Content type: Research article

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  22. Even though evidence based medicine, guidelines and algorithms still represent the pillars of the management of chronic diseases (i.e: hypertension, diabetes mellitus), a patient centred approach has been rece...

    Authors: Cosimo De Nunzio, Fabrizio Presicce, Riccardo Lombardo, Alberto Trucchi, Mariangela Bellangino, Andrea Tubaro and Egidio Moja

    Citation: BMC Urology 2018 18:62

    Content type: Research article

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  23. Αim of the study was to determine the effect of mirabegron, used for overactive bladder (OAB) treatment, on female sexual function.

    Authors: A. Zachariou, C. Mamoulakis, M. Filiponi, F. Dimitriadis, J. Giannakis, S. Skouros, P. Tsounapi, A. Takenaka and N. Sofikitis

    Citation: BMC Urology 2018 18:61

    Content type: Research article

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  24. The preoperative neutrophil-to-lymphocyte ratio (NLR), C-reactive protein/albumin ratio (CRP/Alb ratio) and platelet-to-lymphocyte ratio (PLR) have been demonstrated to predict the clinical outcome of various ...

    Authors: Sezim Agizamhan, Feng Qu, Ning Liu, Jing Sun, Wei Xu, Lihua Zhang, Hongqian Guo and Weidong Gan

    Citation: BMC Urology 2018 18:60

    Content type: Research article

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  25. Epidermal growth factor receptor (EGFR) has been shown to have abnormal expression in many human cancers and is considered as a marker of poor prognosis. Frequency of over expression in bladder cancer has not ...

    Authors: Atif Ali hashmi, Zubaida Fida Hussain, Muhammad Irfan, Erum Yousuf Khan, Naveen Faridi, Hanna Naqvi, Amir Khan and Muhammad Muzzammil Edhi

    Citation: BMC Urology 2018 18:59

    Content type: Research article

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  27. Xanthogranulomatous pyelonephritis (XGP) is an uncommon infectious disease of the kidney known to mimic other renal maladies. A rare presentation of this uncommon disease is spontaneous renal hemorrhage (SRH).

    Authors: William Keith Ballentine III, Fernandino Vilson, Raymond B Dyer and Majid Mirzazadeh

    Citation: BMC Urology 2018 18:57

    Content type: Case report

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  28. Overactive bladder (OAB) affects millions of women. It is important to assess knowledge and attitude in affected patients. The study objective was to develop surveys to assess OAB knowledge and OAB related att...

    Authors: Sumedha Chhatre, Diane K. Newman, Alan J. Wein, Ashlie E. Jefferson, J. Sanford Schwartz and Ravishankar Jayadevappa

    Citation: BMC Urology 2018 18:56

    Content type: Research article

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  29. The objective of this study was to describe overall survival and the management of men with favorable risk prostate cancer (PCa) within a large community-based health care system in the United States.

    Authors: Furaha Kariburyo, Yuexi Wang, I-Ning ( Elaine) Cheng, Lisa Wang, David Morgenstern, Lin Xie, Eric Meadows, John Danella and Michael L. Cher

    Citation: BMC Urology 2018 18:55

    Content type: Research article

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  30. Recurrent (stuttering) ischemic priapism is a challenging clinical condition. Frequent recurrences result in frequent hospital admissions whereas treatment with a shunting procedure often results in erectile d...

    Authors: Paolo Massenio, Nicola D’Altilia, Francesca Sanguedolce, Giuseppe Carrieri and Luigi Cormio

    Citation: BMC Urology 2018 18:54

    Content type: Case report

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  31. This study aims to explore the feasibility of anchoring a four-arm transvaginal mesh (TVM) to the mid-urethra to correct an anterior compartment POP–Quantification stage II–III (Q II–III) and concomitant genuine ...

    Authors: Zoltán Fekete, Szilvia Kőrösi, László Pajor, Zoltán Bajory, Gábor Németh and Zoltan Kozinszky

    Citation: BMC Urology 2018 18:53

    Content type: Research article

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  32. This study was conducted to determine whether the location of the bladder neck in postoperative cystography predicts recovery of continence after radical prostatectomy.

    Authors: Susumu Kageyama, Tetsuya Yoshida, Masayuki Nagasawa, Shigehisa Kubota, Keiji Tomita, Kenichi Kobayashi, Ryosuke Murai, Teruhiko Tsuru, Eiki Hanada, Kazuyoshi Johnin, Mitsuhiro Narita and Akihiro Kawauchi

    Citation: BMC Urology 2018 18:52

    Content type: Research article

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  33. To determine whether prebiopsy multiparametric magnetic resonance imaging (mpMRI) with subsequent systematic plus targeted biopsies for suspicious lesions improve prostate cancer detection compared with standa...

    Authors: Satoshi Washino, Shigeru Kobayashi, Tomohisa Okochi, Tomohiro Kameda, Tsuzumi Konoshi, Tomoaki Miyagawa, Tatsuya Takayama and Tatsuo Morita

    Citation: BMC Urology 2018 18:51

    Content type: Research article

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  34. The objectives of this study were to determine the minimum incidence of penile cancer in the poorest Brazilian state, and to describe the epidemiologic and clinical characteristics of patients diagnosed with t...

    Authors: Ronald Wagner Pereira Coelho, Jaqueline Diniz Pinho, Janise Silva Moreno, Dimitrius Vidal e Oliveira Garbis, Athiene Maniva Teixeira do Nascimento, Joyce Santos Larges, José Ribamar Rodrigues Calixto, Leandra Naira Zambelli Ramalho, Antônio Augusto Moura da Silva, Leudivan Ribeiro Nogueira, Laisson de Moura Feitoza and Gyl Eanes Barros Silva

    Citation: BMC Urology 2018 18:50

    Content type: Research article

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  35. Long-term use of indwelling urethral catheters is associated with high risk of urinary tract infection (UTI) and blockage, which may in turn cause significant morbidity and reduce the life of the catheter. A 0...

    Authors: Florian H. H. Brill, Henrik Gabriel, Holger Brill, Jan-Hendrik Klock, Joerg Steinmann and Andreas Arndt

    Citation: BMC Urology 2018 18:49

    Content type: Research article

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  36. The aim of this study is to assess the value of contrast-enhanced ultrasound (CEUS) as a new non-invasive approach to locate the testicular area in which spermatogenesis is most likely to be found in non-obstr...

    Authors: Shijun Zhang, Jing Du, Ruhui Tian, Shaowei Xie, Fenghua Li and Zheng Li

    Citation: BMC Urology 2018 18:48

    Content type: Research article

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  37. Although the pelvic autonomic plexus branches are considered to be a mixture of sympathetic and parasympathetic nerves, little is known regarding the composite fibers of the pelvic plexus branches. This study ...

    Authors: Kuniyasu Muraoka, Shuichi Morizane, Keisuke Hieda, Masashi Honda, Takehiro Sejima, Gen Murakami, Shin-ichi Abe and Atsushi Takenaka

    Citation: BMC Urology 2018 18:47

    Content type: Research article

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  38. The incidence of posterior urethral valve (PUV) is estimated at 1:5000–1:8000 males. It is the most common paediatric urologic urgency and the most common cause of male obstructive uropathy and chronic renal f...

    Authors: Faustin Felicien Mouafo Tambo, Paul Nkemtendong Tolefac, Marcelin Ngowe Ngowe, Jacqueline Ze Minkande, Landry Mbouche, Georgette Guemkam, Neville Alemnju Telelen, Fru Fobuzshi Angwafo III and Aurelien Maurice Sosso

    Citation: BMC Urology 2018 18:46

    Content type: Research article

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  39. Urinary tract infection (UTI) is very common in patients with urolithiasis, which makes the treatment of urolithiasis complicated, even dangerous. The objective of this study was to determine the risk factors ...

    Authors: Li Yongzhi, Yan Shi, Liu Jia, Liu Yili, Zhu Xingwang and Gong Xue

    Citation: BMC Urology 2018 18:45

    Content type: Research article

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  40. Adjustable single-incision mini-sling (SIMS) is a new category of SIMS for stress urinary incontinence (SUI). The aim of this study was to compare the efficacy and safety of adjustable single-incision mini-sli...

    Authors: Fuding Bai, Jimin Chen, Zhewei Zhang, Yichun Zheng, Jiaming Wen, Xiawa Mao and Nan Zhang

    Citation: BMC Urology 2018 18:44

    Content type: Research article

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  41. Hospital length of stay (LOS) has recently been receiving increasing attention as a marker of medical resource consumption. Identifying predictors of longer LOS can better equip doctors to counsel patients and...

    Authors: Qingmei Huang, Ping Jiang, Lina Feng, Liping Xie, Shuo Wang, Dan Xia, Baihua Shen, Baiye Jin, Li Zheng and Wei Wang

    Citation: BMC Urology 2018 18:43

    Content type: Research article

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  44. Primary synovial sarcoma of the kidney is a rare type of soft tissue sarcoma. Its presenting features can resemble those of other renal tumors; rendering its early diagnosis, a dilemma. Several cases of renal ...

    Authors: Alissar El Chediak, Deborah Mukherji, Sally Temraz, Samer Nassif, Sara Sinno, Rami Mahfouz and Ali Shamseddine

    Citation: BMC Urology 2018 18:40

    Content type: Case report

    Published on:

  45. Living-donor nephrectomy (LDN) is challenging, as surgery is performed on healthy individuals. Minimally invasive techniques for LDN have become standard in most centers. Nevertheless, numerous techniques have...

    Authors: Jeannette D. Widmer, Andrea Schlegel, Philipp Kron, Marc Schiesser, Jens G. Brockmann and Markus K. Muller

    Citation: BMC Urology 2018 18:39

    Content type: Research article

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  46. Multiple guidelines seek to alter rates of prostate-specific antigen (PSA)-based prostate cancer screening. The costs borne by payers associated with PSA-based screening for men of different age groups—includi...

    Authors: Karthik Rao, Stella Liang, Michael Cardamone, Corinne E. Joshu, Kyle Marmen, Nrupen Bhavsar, William G. Nelson, H. Ballentine Carter, Michael C. Albert, Elizabeth A. Platz and Craig E. Pollack

    Citation: BMC Urology 2018 18:38

    Content type: Research article

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  47. Penile length (PL) shortening is an underreported phenomenon following radical prostatectomy (RP) and risk factors are not fully explored. We aimed to describe longitudinal patterns of PL recovery and evaluate...

    Authors: Young Suk Kwon, Nicholas Farber, Ji Woong Yu, Kevin Rhee, Christopher Han, Patrick Ney, Jeong Hee Hong, Paul Lee, Nikhil Gupta, Wun-Jae Kim and Isaac Yi Kim

    Citation: BMC Urology 2018 18:37

    Content type: Research article

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  48. Urologists frequently encounter malignant ureteral obstruction (MUO) caused by advanced urological or non-urological malignant disease, but the treatment policy is unclear. The present study examined the risk ...

    Authors: Mari Ohtaka, Takashi Kawahara, Daiji Takamoto, Taku Mochizuki, Yusuke Hattori, Jun-ichi Teranishi, Kazuhide Makiyama, Yasuhide Miyoshi, Yasushi Yumura, Masahiro Yao and Hiroji Uemura

    Citation: BMC Urology 2018 18:35

    Content type: Research article

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  49. To observe the efficacy of self-help position therapy (SHPT) after holmium laser lithotripsy via flexible ureteroscopy (FURS).

    Authors: Jie Yang, Rong-zhen Tao, Pei Lu, Meng-xing Chen, Xin-kun Huang, Ke-liang Chen, Ying-heng Huang, Xiao-rong He, Li-di Wan, Jing Wang, Xin Tang and Wei Zhang

    Citation: BMC Urology 2018 18:33

    Content type: Research article

    Published on:

  50. Less evidence is known about the role of early changes in serum biomarker after androgen deprivation therapy (ADT) in patients with metastatic hormone-sensitive prostate cancer (mHSPC). Here we evaluated the i...

    Authors: Hiromi Sato, Shintaro Narita, Norihiko Tsuchiya, Atsushi Koizumi, Taketoshi Nara, Sohei Kanda, Kazuyuki Numakura, Hiroshi Tsuruta, Atsushi Maeno, Mitsuru Saito, Takamitsu Inoue, Shigeru Satoh, Kyoko Nomura and Tomonori Habuchi

    Citation: BMC Urology 2018 18:32

    Content type: Research article

    Published on:

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