Articles

Assessing health-related quality of life in urology – a survey of 4500 German urologists

Urological diseases and their treatment may negatively influence continence, potency, and health-related quality of life (HRQOL). Although current guidelines recommend HRQOL assessment in clinical urology, spe...

Authors: A. Schmick, M. Juergensen, V. Rohde, A. Katalinic and A. Waldmann

Life after prostate cancer treatment: a mixed methods study of the experiences of men with sexual dysfunction and their partners

Prostate cancer is the most common non-skin cancer in men and sexual dysfunction is the most frequently reported long-term side effect of prostate cancer surgery or radiation. The aim of this study was to exam...

Authors: Jeffrey A. Albaugh, Nat Sufrin, Brittany R. Lapin, Jacqueline Petkewicz and Sandi Tenfelde

The usefulness of flexible cystoscopy for preventing double-J stent malposition after laparoscopic ureterolithotomy

The aim of this study was to evaluate the role of flexible cystoscopy in preventing malpositioning of the ureteral stent after laparoscopic ureterolithotomy in male patients.

Authors: Jae-Yoon Kim, Seok-Ho Kang, Jun Cheon, Jeong-Gu Lee, Je-Jong Kim and Sung-Gu Kang

Intravenous misplacement of the nephrostomy catheter following percutaneous nephrostolithotomy: two case reports and literature review

Intravenous misplacement of a nephrostomy tube after percutaneous nephrostolithotomy (PCNL) is very rare in clinical experiences. This report summarizes the characteristics and management of intravenous mispla...

Authors: Weijin Fu, Zhanbin Yang, Zhibin Xie and Haibiao Yan

Toileting behaviors and overactive bladder in patients with type 2 diabetes: a cross-sectional study in China

Overactive bladder is more prevalent in patients with type 2 diabetes than in those without diabetes. Unhealthy toileting behaviors may be associated with the development and worsening of overactive bladder sy...

Authors: Dongjuan Xu, Ran Cheng, Aixia Ma, Meng Zhao and Kefang Wang

When to perform bone scintigraphy in patients with newly diagnosed prostate cancer? a retrospective study

To determine when a bone scintigraphy investigation is appropriate in patients with newly diagnosed prostate cancer (PCa).

Authors: Yiwei Lin, Qiqi Mao, Bin Chen, Liujiang Wang, Ben Liu, Xiangyi Zheng and Liping Xie

Jack stone in the bladder: case report of a rare entity

Jackstone is a bladder stone that has a similar appearance to toy jacks. However review of the English language medical literature revealed only a few previous reports of jackstone calculus.

Authors: Duminda Subasinghe, Serozsha Goonewardena and Vickneswaran Kathiragamathamby

Predictors of survival outcomes in native sub Saharan black men newly diagnosed with metastatic prostate cancer

Though it is well established that black men are at higher risk of prostate cancer (PCa) very little is known about the disease in native sub Saharan black men. Newly diagnosed metastatic PCa patients treated ...

Authors: Jibril Oyekunle Bello

Anti-proliferative potential of Glucosamine in renal cancer cells via inducing cell cycle arrest at G0/G1 phase

Renal cell carcinoma (RCC) is one of the most common types of cancer in urological system worldwide. Recently, the anticancer role of Glucosamine has been studied in many types of cancer. The aim of this study...

Authors: Long-sheng Wang, Shao-jun Chen, Jun-feng Zhang, Meng-nan Liu, Jun-hua Zheng and Xu-dong Yao

A rare presentation of metastatic prostate cancer, initially a suspect for urothelial cell carcinoma of the ureter: a case report

The most common metastatic sites of prostate cancer are the lymph nodes and bone. Ureteral metastasis from prostate cancer is very unusual and only a few cases have been reported.

Authors: Ho Seok Chung, Myung Soo Kim, Yang Hyun Cho, Eu Chang Hwang, Seung Il Jung, Taek Won Kang, Dong Deuk Kwon, Suk Hee Heo and Chan Choi

A retrospective study of treatment persistence and adherence to α-blocker plus antimuscarinic combination therapies, in men with LUTS/BPH in the Netherlands

To assess treatment persistence and adherence in men ≥45 years of age with lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH), using prescription records from the Netherland...

Authors: Marcus J. Drake, Sally Bowditch, Emilio Arbe, Zalmai Hakimi, Florent Guelfucci, Ikbel Amri and Jameel Nazir

Qualitative insights into how men with low-risk prostate cancer choosing active surveillance negotiate stress and uncertainty

Active surveillance is a management strategy for men diagnosed with early-stage, low-risk prostate cancer in which their cancer is monitored and treatment is delayed. This study investigated the primary coping...

Authors: Emily M. Mader, Hsin H. Li, Kathleen D. Lyons, Christopher P. Morley, Margaret K. Formica, Scott D. Perrapato, Brian H. Irwin, John D. Seigne, Elias S. Hyams, Terry Mosher, Mark T. Hegel and Telisa M. Stewart

Lymphoepithelioma-like, a variant of urothelial carcinoma of the urinary bladder: a case report and systematic review for optimal treatment modality for disease-free survival

Lymphoepithelioma-like carcinoma (LELC) is a rare high-grade carcinoma that resembles nasopharyngeal lymphoepithelioma and can occur throughout the body. First reported in 1991, bladder LELC has an incidence o...

Authors: Andy W. Yang, Aydin Pooli, Subodh M. Lele, Ina W. Kim, Judson D. Davies and Chad A. LaGrange

The susceptibility to fosfomycin of Gram-negative bacteria isolates from urinary tract infection in the Czech Republic: data from a unicentric study

Against a background of rapid increase of β-lactamase-producing or multi-resistant pathogenic bacteria and the resulting lack of effective antibiotic treatment, some older antibiotics have been tested for new ...

Authors: Miroslav Fajfr, Miroslav Louda, Pavla Paterová, Lenka Ryšková, Jaroslav Pacovský, Josef Košina, Helena Žemličková and Miloš Broďák

A prospective and randomized comparison of rigid ureteroscopic to flexible cystoscopic retrieval of ureteral stents

Flexible cystoscopy has become an accepted alternative for stent retrieval. However, it is associated with higher cost. Some reports have described experiences of using rigid ureteroscope to retrieve ureteral ...

Authors: Dehui Lai, Meiling Chen, Shifang Zha and Shawpong Wan

The role of flower pollen extract in managing patients affected by chronic prostatitis/chronic pelvic pain syndrome: a comprehensive analysis of all published clinical trials

Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is still a challenge to manage for all physicians. We feel that a summary of the current literature and a systematic review to evaluate the therapeuti...

Authors: Tommaso Cai, Paolo Verze, Roberto La Rocca, Umberto Anceschi, Cosimo De Nunzio and Vincenzo Mirone

Real life persistence rate with antimuscarinic treatment in patients with idiopathic or neurogenic overactive bladder: a prospective cohort study with solifenacin

Several studies have shown that the antimuscarinic treatment of overactive bladder is characterized by low long-term persistence rates. We have investigated the persistence of solifenacin in real life by means...

Authors: Marloes J. Tijnagel, Jeroen R. Scheepe and Bertil F. M. Blok

Urinary incontinence, mental health and loneliness among community-dwelling older adults in Ireland

Urinary incontinence (UI) is associated with worse health among older adults. Little is known however, about its relation with loneliness or the role of mental health in this association. This study examined t...

Authors: Andrew Stickley, Ziggi Ivan Santini and Ai Koyanagi

The prostate cancer detection rates of CEUS-targeted versus MRI-targeted versus systematic TRUS-guided biopsies in biopsy-naïve men: a prospective, comparative clinical trial using the same patients

The current standard for Prostate Cancer (PCa) detection in biopsy-naïve men consists of 10–12 systematic biopsies under ultrasound guidance. This approach leads to underdiagnosis and undergrading of significa...

Authors: A. W. Postema, M. J. V. Scheltema, C. K. Mannaerts, R. J. G. Van Sloun, T. Idzenga, M. Mischi, M. R. E. Engelbrecht, J. J. M. C. H. De la Rosette and H. Wijkstra

A rare diaphragmatic ureteral herniation case report: endoscopic and open reconstructive management

Ureteral herniations are a rare occurrence, generally found incidentally on cross sectional imaging or during surgical intervention for unrelated processes. Several locations of ureteral herniations can occur ...

Authors: Frank C. Lin, Jamie S. Lin, Samuel Kim and Jonathan R. Walker

Transperineal template-guided saturation biopsy aimed at sampling one core for each milliliter of prostate volume: 103 cases requiring repeat prostate biopsy

We evaluated the cancer detection rate of prostate cancer using transperineal template-guided saturation biopsy aimed at sampling one core for each milliliter of prostate volume for patients requiring repeated...

Authors: Yasushi Nakai, Nobumichi Tanaka, Satoshi Anai, Makito Miyake, Shunta Hori, Yoshihiro Tatsumi, Yosuke Morizawa, Tomomi Fujii, Noboru Konishi and Kiyohide Fujimoto

Clinical relevance of aortic calcification in urolithiasis patients

The aim of the present study is to investigate the clinical relevance of aortic calcification in urolithiasis patients.

Authors: Toshikazu Tanaka, Shingo Hatakeyama, Hayato Yamamoto, Takuma Narita, Itsuto Hamano, Teppei Matsumoto, Osamu Soma, Yuki Tobisawa, Tohru Yoneyama, Takahiro Yoneyama, Yasuhiro Hashimoto, Takuya Koie, Ippei Takahashi, Shigeyuki Nakaji, Yuriko Terayama, Tomihisa Funyu…

Different expression of B7-H3 in the caput, corpus, and cauda of the epididymis in mouse

B7-H3, a member of the B7 family of the Ig superfamily of proteins, has been detected in the epididymis, which is a storage organ related to sperm maturation. However, the characteristics of its expression in ...

Authors: Kai Li, Xuedong Wei, Guangbo Zhang, Miao Li, Xuefeng Zhang, Chenhao Zhou, Jianquan Hou and Hexing Yuan

Rare adrenal gland incidentaloma: an unusual Ewing’s sarcoma family of tumor presentation and literature review

Members of the Ewing’s sarcoma family of tumor (ESFT) are malignant neoplasms and rarely observed in the adrenal gland.

Authors: Hui Guo, Shuaiqi Chen, Shukun Liu, Kaixuan Wang, Erpeng Liu, Faping Li and Yuchuan Hou

Benign prostatic enlargement can be influenced by metabolic profile: results of a multicenter prospective study

In last years Metabolic Syndrome (MetS) has been closely associated to Benign Prostatic Enlargement (BPE) Aim of our study is to evaluate the effect of MetS and each single MetS parameter on prostate growth in...

Authors: Mauro Gacci, Arcangelo Sebastianelli, Matteo Salvi, Cosimo De Nunzio, Linda Vignozzi, Giovanni Corona, Tommaso Jaeger, Tommaso Chini, Giorgio Ivan Russo, Mario Maggi, Giuseppe Morgia, Andrea Tubaro, Marco Carini and Sergio Serni

Evaluation and treatment for ovotesticular disorder of sex development (OT-DSD) - experience based on a Chinese series

The aim of this study is to review and present the clinical features and process of evaluation and treatment for OT-DSD in a single center in recent years in China.

Authors: Yu Mao, Shaoji Chen, Ru Wang, Xuejun Wang, Daorui Qin and Yunman Tang

Erratum to: Patient preferences for treatment of castration-resistant prostate cancer in Japan: a discrete-choice experiment

Authors: Hiroji Uemura, Nobuaki Matsubara, Go Kimura, Akito Yamaguchi, Dianne Athene Ledesma, Marco DiBonaventura, Ateesha F. Mohamed, Enrique Basurto, Ian McKinnon, Ed Wang, Kristen Concialdi, Aya Narimatsu and Yasuko Aitoku

BAP1 and PBRM1 in metastatic clear cell renal cell carcinoma: tumor heterogeneity and concordance with paired primary tumor

BAP1 and PBRM1 are frequently mutated in primary clear cell renal cell carcinoma (ccRCC) tumors; however, the frequency and clinical relevance of these mutations in metastatic ccRCC tumors is unknown. Addition...

Authors: Jeanette E. Eckel-Passow, Daniel J. Serie, John C. Cheville, Thai H. Ho, Payal Kapur, James Brugarolas, R. Houston Thompson, Bradley C. Leibovich, Eugene D. Kwon, Richard W. Joseph and Alexander S. Parker

miRNAs associated with prostate cancer risk and progression

Prostate cancer is the most common malignancy among men in the US. Though considerable improvement in the diagnosis of prostate cancer has been achieved in the past decade, predicting disease outcome remains a...

Authors: Hung N. Luu, Hui-Yi Lin, Karina Dalsgaard Sørensen, Olorunseun O. Ogunwobi, Nagi Kumar, Ganna Chornokur, Catherine Phelan, Dominique Jones, LaCreis Kidd, Jyotsna Batra, Kosj Yamoah, Anders Berglund, Robert J. Rounbehler, Mihi Yang, Sang Haak Lee, Nahyeon Kang…

Multicystic nephroma masquerading as hydatid cyst: a diagnostic challenge

Multicystic nephroma is an uncommon, non-familial renal neoplasm that is usually benign. About 200 cases of this lesion have been described in the literature.

Authors: Abdelmoneim E. M. Kheir, Aziza M. Elnaeema, Sara M. A. Gafer, Sawsan A. Mohammed and Mustafa E. Bahar

The resonance® metallic ureteric stent in the treatment of chronic ureteric obstruction: a safety and efficacy analysis from a contemporary clinical series

We evaluate the efficacy and safety of metallic ureteric stenting using the Cook Resonance® stent in the treatment of chronic ureteric obstruction of benign and malignant aetiology. Published experience of usi...

Authors: C. Patel, D. Loughran, R. Jones, M. Abdulmajed and I. Shergill

Multi-tract percutaneous nephrolithotomy combined with EMS lithotripsy for bilateral complex renal stones: our experience

The treatment of bilateral complex renal stones is a tough challenge for urologists. This study aimed to evaluate the efficiency and safety of bilateral ultrasonography-guided multi-tract percutaneous nephroli...

Authors: Taisheng Liang, Chenming Zhao, Gang Wu, Botao Tang, Xiangdong Luo, Shangguang Lu, Yu Dong and Huan Yang

Anti-tumor effects of a recombinant anti-prostate specific membrane antigen immunotoxin against prostate cancer cells

To evaluate anti-prostate cancer effects of a chimeric tumor-targeted killer protein.

Authors: Ping Meng, Qing-chuan Dong, Guang-guo Tan, Wei-hong Wen, He Wang, Geng Zhang, Yan-zhu Wang, Yu-ming Jing, Chen Wang, Wei-jun Qin and Jian-lin Yuan

Aortic calcification burden predicts deterioration of renal function after radical nephrectomy

Radical nephrectomy for renal cell carcinoma (RCC) is a risk factor for the development of chronic kidney disease (CKD), and the possibility of postoperative deterioration of renal function must be considered ...

Authors: Ken Fukushi, Shingo Hatakeyama, Hayato Yamamoto, Yuki Tobisawa, Tohru Yoneyama, Osamu Soma, Teppei Matsumoto, Itsuto Hamano, Takuma Narita, Atsushi Imai, Takahiro Yoneyama, Yasuhiro Hashimoto, Takuya Koie, Yuriko Terayama, Tomihisa Funyu and Chikara Ohyama

Genetic polymorphisms in key hypoxia-regulated downstream molecules and phenotypic correlation in prostate cancer

In this study we sought if, in their quest to handle hypoxia, prostate tumors express target hypoxia-associated molecules and their correlation with putative functional genetic polymorphisms.

Authors: Avelino Fraga, Ricardo Ribeiro, André Coelho, José Ramon Vizcaíno, Helena Coutinho, José Manuel Lopes, Paulo Príncipe, Carlos Lobato, Carlos Lopes and Rui Medeiros

Do men regret prostate biopsy: Results from the PiCTure study

Understanding men’s experience of prostate biopsy is important as the procedure is common, invasive and carries potential risks. The psychological aspects of prostate biopsy have been somewhat neglected. The a...

Authors: Catherine Coyle, Eileen Morgan, Frances J. Drummond, Linda Sharp and Anna Gavin

Percutaneous nephrolithotomy versus retrograde intrarenal surgery for the treatment of kidney stones up to 2 cm in patients with solitary kidney: a single centre experience

To compare the treatment outcomes between percutaneous nephrolithotomy (PCNL) and retrograde intrarenal surgery (RIRS) for the management of stones larger than 2 cm in patients with solitary kidney.

Authors: Yunjin Bai, Xiaoming Wang, Yubo Yang, Ping Han and Jia Wang

Preoperative lipiodol marking and its role on survival and complication rates of CT-guided cryoablation for small renal masses

Partial nephrectomy for small renal masses (SRM) may be useful for preserving renal function, but is technically more difficult than radical nephrectomy. Cryoablation may be performed under local anesthesia. T...

Authors: Fumiya Hongo, Yasuhiro Yamada, Takashi Ueda, Terukazu Nakmura, Yoshio Naya, Kazumi Kamoi, Koji Okihara, Yusuke Ichijo, Tsuneharu Miki, Kei Yamada and Osamu Ukimura

PD-L1 expression in papillary renal cell carcinoma

The immune escape or tolerance of cancer cells is considered to be closely involved in cancer progression. Programmed death-1 (PD-1) is an inhibitory receptor expressed on activating T cells, and several types...

Authors: Takanobu Motoshima, Yoshihiro Komohara, Chaoya Ma, Arni Kusuma Dewi, Hirotsugu Noguchi, Sohsuke Yamada, Toshiyuki Nakayama, Shohei Kitada, Yoshiaki Kawano, Wataru Takahashi, Masaaki Sugimoto, Motohiro Takeya, Naohiro Fujimoto, Yoshinao Oda and Masatoshi Eto

The addition of a sagittal image fusion improves the prostate cancer detection in a sensor-based MRI /ultrasound fusion guided targeted biopsy

To explore the diagnostic benefit of an additional image fusion of the sagittal plane in addition to the standard axial image fusion, using a sensor-based MRI/US fusion platform.

Authors: Karsten Günzel, Hannes Cash, John Buckendahl, Maximilian Königbauer, Patrick Asbach, Matthias Haas, Jörg Neymeyer, Stefan Hinz, Kurt Miller and Carsten Kempkensteffen

Bilateral benign renal oncocytomas and the role of renal biopsy: single institution review

The goal was to assess the natural history and management of patients with pathologically proven bilateral (synchronous) RO after undergoing initial partial nephrectomy (PN).

Authors: Andrew R. Leone, Laura C. Kidd, Gregory J. Diorio, Kamran Zargar-Shoshtari, Pranav Sharma, Wade J. Sexton and Philippe E. Spiess

Quality of life and functional outcome after infravesical desobstruction and HIFU treatment for localized prostate cancer

To evaluate quality of life, functional and oncological outcome after infravesical desobstruction and HIFU treatment for localized prostate cancer.

Authors: G. Hatiboglu, I. V. Popeneciu, M. Deppert, J. Nyarangi-Dix, B. Hadaschik, M. Hohenfellner, D. Teber and S. Pahernik

Intermittent catheterisation with hydrophilic and non-hydrophilic urinary catheters: systematic literature review and meta-analyses

Intermittent catheterisation is the method of choice for the management of bladder dysfunctions. Different urinary catheters are available, but there is conflicting evidence on which type of catheter is best. ...

Authors: Carla Rognoni and Rosanna Tarricone

The “Guidewire-Coil”-Technique to prevent retrograde stone migration of ureteric calculi during intracorporeal lithothripsy

Stone retropulsion represents a challenge for intracorporeal lithotripsy of ureteral calculi. The consequences are an increased duration and cost of surgery as well as decreased stone-free rates. The use of ad...

Authors: Nici Markus Dreger, Friedrich Carl von Rundstedt, Stephan Roth, Alexander Sascha Brandt and Stephan Degener

Fulranumab in patients with interstitial cystitis/bladder pain syndrome: observations from a randomized, double-blind, placebo-controlled study

This study was designed to evaluate the efficacy and safety of fulranumab, a fully human monoclonal antibody directed against nerve growth factor (NGF), for pain relief in patients with interstitial cystitis/b...

Authors: Hao Wang, Lucille J. Russell, Kathleen M. Kelly, Steven Wang and John Thipphawong

Neutrophil-lymphocyte ratio as a predictive biomarker for response to high dose interleukin-2 in patients with renal cell carcinoma

Immunotherapy with high-dose interleukin-2 (HD-IL2) results in long-term survival in some metastatic renal cell carcinoma (mRCC) patients but has significant acute toxicities. Biomarkers predicting response to...

Authors: James A. Kuzman, David D. Stenehjem, Joseph Merriman, Archana M. Agarwal, Shiven B. Patel, Andrew W. Hahn, Anitha Alex, Dan Albertson, David M. Gill and Neeraj Agarwal

A Randomized Study of Minimally Invasive Percutaneous Nephrolithotomy (MPCNL) with the aid of a patented suctioning sheath in the treatment of renal calculus complicated by pyonephrosis by one surgery

Calculus pyonephrosis is difficult to manage. The aim of this study is to explore the value of a patented suctioning sheath assisted minimally invasive percutaneous nephrolithotomy (MPCNL) in the treatment of ...

Authors: Jianrong Huang, Leming Song, Donghua Xie, Monong Li, Xiaolin Deng, Min Hu, Zuofeng Peng, Tairong Liu, Chuance Du, Lei Yao, Shengfeng Liu, Shulin Guo and Jiuqing Zhong

Developing a preoperative predictive model for ureteral length for ureteral stent insertion

Ureteral stenting has been a fundamental part of various urological procedures. Selecting a ureteral stent of optimal length is important for decreasing the incidence of stent migration and complications. The ...

Authors: Takashi Kawahara, Kentaro Sakamaki, Hiroki Ito, Shinnosuke Kuroda, Hideyuki Terao, Kazuhide Makiyama, Hiroji Uemura, Masahiro Yao, Hiroshi Miyamoto and Junichi Matsuzaki

Protocol for a prospective, randomized study on neurophysiological assessment of lower urinary tract function in a healthy cohort

Lower urinary tract symptoms are highly prevalent and a large proportion of these symptoms are known to be associated with a dysfunction of the afferent pathways. Diagnostic tools for an objective and reproduc...

Authors: Stéphanie van der Lely, Martina Stefanovic, Melanie R. Schmidhalter, Marta Pittavino, Reinhard Furrer, Martina D. Liechti, Martin Schubert, Thomas M. Kessler and Ulrich Mehnert

Comparison of the complications of traditional 12 cores transrectal prostate biopsy with image fusion guided transperineal prostate biopsy

To compare the complications of traditional transrectal (TR) prostate biopsy and image fusion guided transperineal (TP) prostate biopsy in our center.

Authors: Haifeng Huang, Wei Wang, Tingsheng Lin, Qing Zhang, Xiaozhi Zhao, Huibo Lian and Hongqian Guo