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  1. Content type: Research article

    Lower Urinary Tract Symptoms (LUTS) in men are a common clinical problem in urology and have been historically strictly linked to benign prostatic hyperplasia (BPH), which may lead to bladder outlet obstructio...

    Authors: Simone Albisinni, Ibrahim Biaou, Quentin Marcelis, Fouad Aoun, Cosimo De Nunzio and Thierry Roumeguère

    Citation: BMC Urology 2016 16:58

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  2. Content type: Research article

    The aim was to evaluate cancer-specific survival (CSS) and overall survival (OS) in patients with prostate cancer (PCa) recurrence who underwent salvage extended pelvic lymph node dissection (ePLND), taking in...

    Authors: Daniar K. Osmonov, Alexey V. Aksenov, David Trick, Carsten M. Naumann, Moritz F. Hamann, Amr Abou Faddan and Klaus-Peter Jünemann

    Citation: BMC Urology 2016 16:56

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  3. Content type: Research article

    To assess the efficacy and safety of intradetrusor onabotulinumtoxinA (OnabotA) injection treatment in patients with neurogenic lower urinary tract dysfunction (NLUTD), especially for patients with Parkinson d...

    Authors: Stephanie C. Knüpfer, Susanne A. Schneider, Mareike M. Averhoff, Carsten M. Naumann, Günther Deuschl, Klaus-Peter Jünemann and Moritz F. Hamann

    Citation: BMC Urology 2016 16:55

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  4. Content type: Research article

    Men diagnosed with prostate cancer (PCa) in specific regional areas in Victoria, Australia have a poorer five-year survival rate compared to men living elsewhere in Victoria. This study aims to describe patter...

    Authors: Rasa Ruseckaite, Fanny Sampurno, Jeremy Millar, Mark Frydenberg and Sue Evans

    Citation: BMC Urology 2016 16:54

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  5. Content type: Research article

    Previous studies have suggested a greater benefit for various outcomes in men diagnosed with benign prostatic hyperplasia (BPH) who are treated with dutasteride than for men treated with finasteride. This stud...

    Authors: Josephina G. Kuiper, Irene D. Bezemer, Maurice T. Driessen, Averyan Vasylyev, Claus G. Roehrborn, Fernie J. A. Penning-van Beest and Ron M. C. Herings

    Citation: BMC Urology 2016 16:53

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  6. Content type: Research article

    Methylation of the tumor suppressor gene H-cadherin (CDH13) has been reported in many cancers. However, the clinical effect of the CDH13 methylation status of patients with bladder cancer remains to be clarified.

    Authors: Feng Chen, Tao Huang, Yu Ren, Junjun Wei, Zhongguan Lou, Xue Wang, Xiaoxiao Fan, Yirun Chen, Guobin Weng and Xuping Yao

    Citation: BMC Urology 2016 16:52

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  7. Content type: Research article

    Quinolone is recommended as an antimicrobial prophylaxis to prevent infectious complication after transrectal ultrasound-guided biopsy, but the increased appearance of quinolone-resistant organism has raised c...

    Authors: Jung Keun Lee, Sangchul Lee, Sung Kyu Hong, Seok-Soo Byun and Sang Eun Lee

    Citation: BMC Urology 2016 16:51

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  8. Content type: Research article

    Studies have reported that early physical rehabilitation after surgical procedures is associated with improved outcome measured as shorter hospital stay and enhanced recovery. The aim of this study was to expl...

    Authors: E. Angenete, U. Angerås, M. Börjesson, J. Ekelund, M. Gellerstedt, T. Thorsteinsdottir, G. Steineck and E. Haglind

    Citation: BMC Urology 2016 16:50

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  9. Content type: Research article

    To assess the efficacy and safety of the herbal medicine, Weng-li-tong (WLT) as monotherapy or combined with tolterodine in women with overactive bladder (OAB).

    Authors: Dong-dong Xiao, Jian-wei Lv, Xin Xie, Xing-wei Jin, Mu-jun Lu and Yuan Shao

    Citation: BMC Urology 2016 16:49

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  10. Content type: Research article

    The guidelines of the European Association of Urologists (EAU), of the German Society of Nuclear Medicine (DGN), and the European Society for Medical Oncology (ESMO) recommend sentinel lymph node biopsy (SLNB)...

    Authors: Ulf Lützen, Carsten Maik Naumann, Jens Dischinger, Marlies Marx, René Baumann, Yi Zhao, Michael Jüptner, Daniar Osmonov, Katrin Bothe, Klaus-Peter Jünemann and Maaz Zuhayra

    Citation: BMC Urology 2016 16:47

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  11. Content type: Research article

    Androgen deprivation therapy (ADT) is an effective palliation treatment in men with advanced prostate cancer (PC). However, ADT has well documented side effects that could alter the patient’s health-related qu...

    Authors: Nishi Karunasinghe, Yifei Zhu, Dug Yeo Han, Katja Lange, Shuotun Zhu, Alice Wang, Stephanie Ellett, Jonathan Masters, Megan Goudie, Justin Keogh, Benji Benjamin, Michael Holmes and Lynnette R. Ferguson

    Citation: BMC Urology 2016 16:48

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  12. Content type: Research article

    The efficacy and/or tolerability of pazopanib in patients with metastatic renal cell carcinoma (mRCC) have been found to differ in Western and Asian populations. This retrospective multicenter study analyzed t...

    Authors: Moon Jin Kim, Se Hoon Park, Jae-Lyun Lee, Se-Hoon Lee, Su Jin Lee and Ho Yeong Lim

    Citation: BMC Urology 2016 16:46

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  13. Content type: Research article

    Mirabegron is a β3-adrenoreceptor agonist developed for treatment of overactive bladder (OAB). α1-Adrenergic receptor blockers are effective for lower urinary tract symptoms (LUTS) in male patients. However, t...

    Authors: Tomohiro Matsuo, Yasuyoshi Miyata, Katsura Kakoki, Miki Yuzuriha, Akihiro Asai, Kojiro Ohba and Hideki Sakai

    Citation: BMC Urology 2016 16:45

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  14. Content type: Research article

    Ureteropelvic junction obstruction (UPJO) diagnosed prenatally occurs in 1:150 – 1:1200 pregnancies. Although many studies investigating the molecular changes of this obstructed segment have been performed, th...

    Authors: Sabrina Thalita Reis, Kátia R. M. Leite, Nayara Izabel Viana, Roberto Iglesias Lopes, Caio Martins Moura, Renato F. Ivanovic, Marcos Machado, Francisco Tibor Denes, Amilcar Giron, William Carlos Nahas, Miguel Srougi and Carlo C. Passerotti

    Citation: BMC Urology 2016 16:44

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  15. Content type: Research article

    The management of patients with renal cell carcinoma (RCC) with venous tumor thrombus (VTT) is challenging. We report our 15 year experience in the management of patients with RCC with VTT utilizing a multidis...

    Authors: Bishoy A. Gayed, Ramy Youssef, Oussama Darwish, Payal Kapur, Aditya Bagrodia, James Brugarolas, Ganesh Raj, J. Michael DiMaio, Arthur Sagalowsky and Vitaly Margulis

    Citation: BMC Urology 2016 16:43

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  16. Content type: Research article

    To validate the association between obesity and penile cancer at a population level, we conducted a matched case–control study linking the Iowa Department of Motor Vehicles Drivers’ License Database (DLD) with...

    Authors: Kerri T. Barnes, Bradley D. McDowell, Anna Button, Brian J. Smith, Charles F. Lynch and Amit Gupta

    Citation: BMC Urology 2016 16:42

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  17. Content type: Research article

    In Ethiopia, about 9000 fistula cases are estimated to occur every year with an incidence of 2.2/1000 women. This study was aimed to determine obstetric fistula characteristics and surgical repair outcomes amo...

    Authors: Demisew Anemu Sori, Ahadu Workineh Azale and Desta Hiko Gemeda

    Citation: BMC Urology 2016 16:41

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  18. Content type: Research article

    Renal cell carcinoma (RCC) associated with Xp11.2 translocation/TFE3 gene fusion (Xp11.2 RCC) is a rare subtype of RCC which is firstly described as a distinct entity in 2004 so that clinical characteristics o...

    Authors: Xiangming Cheng, Weidong Gan, Gutian Zhang, Xiaogong Li and Hongqian Guo

    Citation: BMC Urology 2016 16:40

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  19. Content type: Research article

    The standard of care in patients with suspected prostate cancer (PCa) is systematic prostate biopsies. This approach leads to unnecessary biopsies in patients without PCa and also to the detection of clinical ...

    Authors: Yngve Nygård, Svein A. Haukaas, Ole J. Halvorsen, Karsten Gravdal, Jannicke Frugård, Lars A. Akslen and Christian Beisland

    Citation: BMC Urology 2016 16:39

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  20. Content type: Research article

    The purpose of this study was to identify risk factors for abscess formation in acute bacterial prostatitis, and to compare treatment outcomes between abscess group and non-abscess group.

    Authors: Dong Sup Lee, Hyun-Sop Choe, Hee Youn Kim, Sun Wook Kim, Sang Rak Bae, Byung Il Yoon and Seung-Ju Lee

    Citation: BMC Urology 2016 16:38

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  21. Content type: Research article

    The currently recommended treatment algorithm for patients with advanced renal cell carcinoma who fail the first-line targeted therapy does not normally include pazopanib as a second-line treatment option. It ...

    Authors: Victor C. Kok and Jung-Tsung Kuo

    Citation: BMC Urology 2016 16:34

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  22. Content type: Research article

    The activation of TRPA1 channel is implicated in hyper-reflexic micturition similar to overactive bladder. In this study, we aimed to investigate the effects of blocking TRPA1 via intrathecal administration of...

    Authors: Zhipeng Chen, Shuqi Du, Chuize Kong, Zhe Zhang and Al-dhabi Mokhtar

    Citation: BMC Urology 2016 16:33

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  23. Content type: Research article

    Osteoporosis is a common consequence of androgen deprivation therapy (ADT) for prostate cancer. Up to 20 % of men on ADT have suffered from fractures within 5 years. The WHO Fracture Risk Assessment Tool (FRAX...

    Authors: Takashi Kawahara, Shusei Fusayasu, Koji Izumi, Yumiko Yokomizo, Hiroki Ito, Yusuke Ito, Kayo Kurita, Kazuhiro Furuya, Hisashi Hasumi, Narihiko Hayashi, Yasuhide Myoshi, Hiroshi Miyamoto, Masahiro Yao and Hiroji Uemura

    Citation: BMC Urology 2016 16:32

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  24. Content type: Research article

    Spectrum effects refer to the phenomenon that test performance varies across subgroups of a population. When spectrum effects occur during diagnostic testing for cancer, difficult patient misdiagnoses can occu...

    Authors: Ajay Gopalakrishna, Thomas A. Longo, Joseph J. Fantony, Richmond Owusu, Wen-Chi Foo, Rajesh Dash and Brant A. Inman

    Citation: BMC Urology 2016 16:30

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  25. Content type: Research article

    Flexible cystoscopy (FC) is one of the most frequently performed urological intervention. Cumulative sum analysis (CUSUM) allows objective assessment of a proceduralist’s performance to ensure acceptable outco...

    Authors: Kenneth R. MacKenzie and Jonathan Aning

    Citation: BMC Urology 2016 16:31

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    The Erratum to this article has been published in BMC Urology 2016 16:57

  26. Content type: Research article

    Among the different organs used for NOTES (natural orifice translumenal endoscopic surgery) technique, the transvaginal approach may be the optimal choice because of a simple and secure closure of colpotomy si...

    Authors: Dechao Wei, Yili Han, Mingchuan Li, Yongxing Wang, Yatong Chen, Yong Luo and Yongguang Jiang

    Citation: BMC Urology 2016 16:29

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  27. Content type: Research article

    To assess the anti-adhesive effect of treatment with hyaluronic acid-carboxymethylcellulose following laparoscopic radical prostatectomy.

    Authors: U-Syn Ha, Jun Sung Koh, Kang Jun Cho, Byung Il Yoon, Kyu Won Lee, Sung Hoo Hong and Ji Youl Lee

    Citation: BMC Urology 2016 16:28

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  28. Content type: Research article

    Nonbacterial prostatitis, together with chronic pelvic pain syndrome, accounts for 90–95 % of prostatitis cases. Anti-inflammatory medications are commonly used to reduce storage/inflammatory symptoms that can...

    Authors: Giorgio Bozzini, Marco Provenzano, Nicolò Buffi, Mauro Seveso, Giovanni Lughezzani, Giorgio Guazzoni, Alberto Mandressi and Gianluigi Taverna

    Citation: BMC Urology 2016 16:25

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  29. Content type: Research article

    We propose to improve the prognostic assessment after radical prostatectomy (RP) by dividing high-risk prostate cancer (hrPCa) (according to the d’Amico classification) into subgroups combining 1, 2 or 3 crite...

    Authors: Jean-Baptiste Beauval, Mathieu Roumiguié, Thomas Filleron, Thibaut Benoit, Alexandre de la Taille, Bernard Malavaud, Laurent Salomon, Michel Soulié and Guillaume Ploussard

    Citation: BMC Urology 2016 16:26

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  30. Content type: Research article

    Previous studies have demonstrated an association between prostate-specific antigen (PSA) kinetics and predictive value for treatment outcomes. Abiraterone acetate (AA) is a newly approved cytochrome-P450C17 i...

    Authors: Masahiko Nakayama, Hisanori Kobayashi, Tomihiro Takahara, Ryo Oyama, Keiichiro Imanaka and Kazutake Yoshizawa

    Citation: BMC Urology 2016 16:27

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  31. Content type: Research article

    Intestinal metaplasia of the bladder is an uncommon glandular proliferation. We examined a large series of intestinal metaplasia for the clinicopathological features and discuss the significance of this lesion.

    Authors: Zhixiang Xin, Chenhui Zhao, Tao Huang, Zhaohui Zhang, Chenlong Chu, Caifeng Lu, Min Wu and Wenlong Zhou

    Citation: BMC Urology 2016 16:24

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  32. Content type: Research article

    Duplex kidney is a common anomaly that is frequently associated with multiple complications. Typical computed tomography urography (CTU) includes four phases (unenhanced, arterial, parenchymal and excretory) a...

    Authors: Honghan Gong, Lei Gao, Xi-Jian Dai, Fuqing Zhou, Ning Zhang, Xianjun Zeng, Jian Jiang and Laichang He

    Citation: BMC Urology 2016 16:21

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  33. Content type: Research article

    The purpose of the study was to investigate whether micro-TESE can improve sperm retrieval rate (SRR) compared to conventional single TESE biopsy on the same testicle or to contralateral multiple TESE, by empl...

    Authors: Giorgio Franco, Filomena Scarselli, Valentina Casciani, Cosimo De Nunzio, Donato Dente, Costantino Leonardo, Pier Francesco Greco, Alessia Greco, Maria Giulia Minasi and Ermanno Greco

    Citation: BMC Urology 2016 16:20

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  34. Content type: Study protocol

    Urinary tract infections [UTIs] are very common in people with Spinal Cord Injury [SCI]. UTIs are increasingly difficult and expensive to treat as the organisms that cause them become more antibiotic resistant...

    Authors: Bonsan Bonne Lee, Swee-Ling Toh, Suzanne Ryan, Judy M. Simpson, Kate Clezy, Laetitia Bossa, Scott A. Rice, Obaydullah Marial, Gerard Weber, Jasbeer Kaur, Claire Boswell-Ruys, Stephen Goodall, James Middleton, Mark Tudehope and George Kotsiou

    Citation: BMC Urology 2016 16:18

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  35. Content type: Research article

    The objective of this study was to determine the factors responsible for peri-operative blood transfusion in a contemporary series of open prostatectomy for benign prostate hyperplasia and thus offer a guide f...

    Authors: Mathew Y. Kyei, George O. Klufio, James E. Mensah, Samuel Gepi-Attee, Kwabena Ampadu, Bernard Toboh and Edward D. Yeboah

    Citation: BMC Urology 2016 16:17

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  36. Content type: Research article

    Human dermal allografts have been used for over a decade for interpositional repair of rectoceles. How do dermal allografts perform with regards to success rate and complications with 8 years’ minimum follow-up?

    Authors: Serge P. Marinkovic, Scott Hughes, Donghua Xie, Lisa M. Gillen and Christina M. Marinkovic

    Citation: BMC Urology 2016 16:16

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  37. Content type: Research article

    [−2]proPSA and its derivatives have an higher diagnostic accuracy than PSA in predicting prostate cancer (PCa). In alternative to PSA, ultrasensitive PSA (uPSA) and [−2]proPSA could be potentially useful in re...

    Authors: S. De Luca, R. Passera, A. Sottile, C. Fiori, R. M. Scarpa and F. Porpiglia

    Citation: BMC Urology 2016 16:14

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  38. Content type: Research article

    A possible role for prostate cancer in Lynch syndrome has been debated based on observations of mismatch-repair defective tumors and reports of an increased risk of prostate cancer in mutation carriers. Potent...

    Authors: Mev Dominguez-Valentin, Patrick Joost, Christina Therkildsen, Mats Jonsson, Eva Rambech and Mef Nilbert

    Citation: BMC Urology 2016 16:15

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  39. Content type: Research article

    There is much interest in confirming whether the efficacy of abiraterone acetate (AA) demonstrated within the trial setting is reproducible in routine clinical practice. We report the clinical outcome of metas...

    Authors: Darren M. C. Poon, Kuen Chan, S. H. Lee, T. W. Chan, Henry Sze, Eric K. C. Lee, Daisy Lam and Michelle F. T. Chan

    Citation: BMC Urology 2016 16:12

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  40. Content type: Research article

    While novel drugs have been developed, docetaxel remains one of the standard initial systemic therapies for castration-resistant prostate cancer (CRPC) patients. Despite the excellent anti-tumor effect of doce...

    Authors: Shimpei Yamashita, Yasuo Kohjimoto, Takashi Iguchi, Hiroyuki Koike, Hiroki Kusumoto, Akinori Iba, Kazuro Kikkawa, Yoshiki Kodama, Nagahide Matsumura and Isao Hara

    Citation: BMC Urology 2016 16:13

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