Table 2 Prognostic factors for survival in all 61 patients
Parameter | Unfavourable prognosis (comparison of actuarial survival curves, log rank test) | Multivariate analysis (Cox proportional hazards model) |
|---|---|---|
Median age (years)* | age > 70 years, p = 0.04 | Not significant |
Median age at first cancer diagnosis (years) | Not significant | |
Median ECOG PS* | Increasing ECOG PS, p = 0.01 | Significant, p = 0.03 |
Median interval (months)** | Not significant | |
Median PSA doubling time (months)** | PSA doubling time < 3 months, p = 0.03 | Not significant |
Median PSA (μg/L)* | Not significant | |
Hb (g/dL)* | Hb ≤ 12.0 g/dL, p = 0.03 | Not significant |
Median ALP (U/L)* | ALP > 118 U/L, p < 0.01 | Significant, p = 0.02 |
Median LDH (U/L)* | LDH > 206 U/L, p < 0.01 | Significant, p = 0.03 |
Hypo- or hypercalcemia* | Not significant | |
Bone pain* | Not significant | |
Gleason score | Not significant | |
Other distant metastases* | Not significant | |
≤10 bone metastases, >10, superscan | Not significant |