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  1. Research article

    A retrospective study of treatment persistence and adherence to α-blocker plus antimuscarinic combination therapies, in men with LUTS/BPH in the Netherlands

    To assess treatment persistence and adherence in men ≥45 years of age with lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH), using prescription records from the Netherland...

    Marcus J. Drake, Sally Bowditch, Emilio Arbe, Zalmai Hakimi, Florent Guelfucci, Ikbel Amri and Jameel Nazir

    BMC Urology 2017 17:36

    Published on: 22 May 2017

  2. Research article

    Qualitative insights into how men with low-risk prostate cancer choosing active surveillance negotiate stress and uncertainty

    Active surveillance is a management strategy for men diagnosed with early-stage, low-risk prostate cancer in which their cancer is monitored and treatment is delayed. This study investigated the primary coping...

    Emily M. Mader, Hsin H. Li, Kathleen D. Lyons, Christopher P. Morley, Margaret K. Formica, Scott D. Perrapato, Brian H. Irwin, John D. Seigne, Elias S. Hyams, Terry Mosher, Mark T. Hegel and Telisa M. Stewart

    BMC Urology 2017 17:35

    Published on: 8 May 2017

  3. Research article

    Lymphoepithelioma-like, a variant of urothelial carcinoma of the urinary bladder: a case report and systematic review for optimal treatment modality for disease-free survival

    Lymphoepithelioma-like carcinoma (LELC) is a rare high-grade carcinoma that resembles nasopharyngeal lymphoepithelioma and can occur throughout the body. First reported in 1991, bladder LELC has an incidence o...

    Andy W. Yang, Aydin Pooli, Subodh M. Lele, Ina W. Kim, Judson D. Davies and Chad A. LaGrange

    BMC Urology 2017 17:34

    Published on: 27 April 2017

  4. Research article

    The susceptibility to fosfomycin of Gram-negative bacteria isolates from urinary tract infection in the Czech Republic: data from a unicentric study

    Against a background of rapid increase of β-lactamase-producing or multi-resistant pathogenic bacteria and the resulting lack of effective antibiotic treatment, some older antibiotics have been tested for new ...

    Miroslav Fajfr, Miroslav Louda, Pavla Paterová, Lenka Ryšková, Jaroslav Pacovský, Josef Košina, Helena Žemličková and Miloš Broďák

    BMC Urology 2017 17:33

    Published on: 26 April 2017

  5. Research article

    The role of flower pollen extract in managing patients affected by chronic prostatitis/chronic pelvic pain syndrome: a comprehensive analysis of all published clinical trials

    Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is still a challenge to manage for all physicians. We feel that a summary of the current literature and a systematic review to evaluate the therapeuti...

    Tommaso Cai, Paolo Verze, Roberto La Rocca, Umberto Anceschi, Cosimo De Nunzio and Vincenzo Mirone

    BMC Urology 2017 17:32

    Published on: 21 April 2017

  6. Research article

    Real life persistence rate with antimuscarinic treatment in patients with idiopathic or neurogenic overactive bladder: a prospective cohort study with solifenacin

    Several studies have shown that the antimuscarinic treatment of overactive bladder is characterized by low long-term persistence rates. We have investigated the persistence of solifenacin in real life by means...

    Marloes J. Tijnagel, Jeroen R. Scheepe and Bertil F. M. Blok

    BMC Urology 2017 17:30

    Published on: 13 April 2017

  7. Research article

    Transperineal template-guided saturation biopsy aimed at sampling one core for each milliliter of prostate volume: 103 cases requiring repeat prostate biopsy

    We evaluated the cancer detection rate of prostate cancer using transperineal template-guided saturation biopsy aimed at sampling one core for each milliliter of prostate volume for patients requiring repeated...

    Yasushi Nakai, Nobumichi Tanaka, Satoshi Anai, Makito Miyake, Shunta Hori, Yoshihiro Tatsumi, Yosuke Morizawa, Tomomi Fujii, Noboru Konishi and Kiyohide Fujimoto

    BMC Urology 2017 17:28

    Published on: 5 April 2017

  8. Study protocol

    The prostate cancer detection rates of CEUS-targeted versus MRI-targeted versus systematic TRUS-guided biopsies in biopsy-naïve men: a prospective, comparative clinical trial using the same patients

    The current standard for Prostate Cancer (PCa) detection in biopsy-naïve men consists of 10–12 systematic biopsies under ultrasound guidance. This approach leads to underdiagnosis and undergrading of significa...

    A. W. Postema, M. J. V. Scheltema, C. K. Mannaerts, R. J. G. Van Sloun, T. Idzenga, M. Mischi, M. R. E. Engelbrecht, J. J. M. C. H. De la Rosette and H. Wijkstra

    BMC Urology 2017 17:27

    Published on: 5 April 2017

  9. Research article

    Benign prostatic enlargement can be influenced by metabolic profile: results of a multicenter prospective study

    In last years Metabolic Syndrome (MetS) has been closely associated to Benign Prostatic Enlargement (BPE) Aim of our study is to evaluate the effect of MetS and each single MetS parameter on prostate growth in...

    Mauro Gacci, Arcangelo Sebastianelli, Matteo Salvi, Cosimo De Nunzio, Linda Vignozzi, Giovanni Corona, Tommaso Jaeger, Tommaso Chini, Giorgio Ivan Russo, Mario Maggi, Giuseppe Morgia, Andrea Tubaro, Marco Carini and Sergio Serni

    BMC Urology 2017 17:22

    Published on: 4 April 2017

  10. Research article

    Clinical relevance of aortic calcification in urolithiasis patients

    The aim of the present study is to investigate the clinical relevance of aortic calcification in urolithiasis patients.

    Toshikazu Tanaka, Shingo Hatakeyama, Hayato Yamamoto, Takuma Narita, Itsuto Hamano, Teppei Matsumoto, Osamu Soma, Yuki Tobisawa, Tohru Yoneyama, Takahiro Yoneyama, Yasuhiro Hashimoto, Takuya Koie, Ippei Takahashi, Shigeyuki Nakaji, Yuriko Terayama, Tomihisa Funyu…

    BMC Urology 2017 17:25

    Published on: 4 April 2017

  11. Research article

    BAP1 and PBRM1 in metastatic clear cell renal cell carcinoma: tumor heterogeneity and concordance with paired primary tumor

    BAP1 and PBRM1 are frequently mutated in primary clear cell renal cell carcinoma (ccRCC) tumors; however, the frequency and clinical relevance of these mutations in metastatic ccRCC tumors is unknown. Addition...

    Jeanette E. Eckel-Passow, Daniel J. Serie, John C. Cheville, Thai H. Ho, Payal Kapur, James Brugarolas, R. Houston Thompson, Bradley C. Leibovich, Eugene D. Kwon, Richard W. Joseph and Alexander S. Parker

    BMC Urology 2017 17:19

    Published on: 21 March 2017

  12. Review

    miRNAs associated with prostate cancer risk and progression

    Prostate cancer is the most common malignancy among men in the US. Though considerable improvement in the diagnosis of prostate cancer has been achieved in the past decade, predicting disease outcome remains a...

    Hung N. Luu, Hui-Yi Lin, Karina Dalsgaard Sørensen, Olorunseun O. Ogunwobi, Nagi Kumar, Ganna Chornokur, Catherine Phelan, Dominique Jones, LaCreis Kidd, Jyotsna Batra, Kosj Yamoah, Anders Berglund, Robert J. Rounbehler, Mihi Yang, Sang Haak Lee, Nahyeon Kang…

    BMC Urology 2017 17:18

    Published on: 20 March 2017

  13. Research article

    The resonance® metallic ureteric stent in the treatment of chronic ureteric obstruction: a safety and efficacy analysis from a contemporary clinical series

    We evaluate the efficacy and safety of metallic ureteric stenting using the Cook Resonance® stent in the treatment of chronic ureteric obstruction of benign and malignant aetiology. Published experience of usi...

    C. Patel, D. Loughran, R. Jones, M. Abdulmajed and I. Shergill

    BMC Urology 2017 17:16

    Published on: 10 March 2017

  14. Research article

    Multi-tract percutaneous nephrolithotomy combined with EMS lithotripsy for bilateral complex renal stones: our experience

    The treatment of bilateral complex renal stones is a tough challenge for urologists. This study aimed to evaluate the efficiency and safety of bilateral ultrasonography-guided multi-tract percutaneous nephroli...

    Taisheng Liang, Chenming Zhao, Gang Wu, Botao Tang, Xiangdong Luo, Shangguang Lu, Yu Dong and Huan Yang

    BMC Urology 2017 17:15

    Published on: 28 February 2017

  15. Research article

    Aortic calcification burden predicts deterioration of renal function after radical nephrectomy

    Radical nephrectomy for renal cell carcinoma (RCC) is a risk factor for the development of chronic kidney disease (CKD), and the possibility of postoperative deterioration of renal function must be considered ...

    Ken Fukushi, Shingo Hatakeyama, Hayato Yamamoto, Yuki Tobisawa, Tohru Yoneyama, Osamu Soma, Teppei Matsumoto, Itsuto Hamano, Takuma Narita, Atsushi Imai, Takahiro Yoneyama, Yasuhiro Hashimoto, Takuya Koie, Yuriko Terayama, Tomihisa Funyu and Chikara Ohyama

    BMC Urology 2017 17:13

    Published on: 6 February 2017

  16. Research article

    Genetic polymorphisms in key hypoxia-regulated downstream molecules and phenotypic correlation in prostate cancer

    In this study we sought if, in their quest to handle hypoxia, prostate tumors express target hypoxia-associated molecules and their correlation with putative functional genetic polymorphisms.

    Avelino Fraga, Ricardo Ribeiro, André Coelho, José Ramon Vizcaíno, Helena Coutinho, José Manuel Lopes, Paulo Príncipe, Carlos Lobato, Carlos Lopes and Rui Medeiros

    BMC Urology 2017 17:12

    Published on: 31 January 2017

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