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Table 3 The correlation between the activities of different uMMPs with clinico-pathological parameters

From: Urinary high molecular weight matrix metalloproteinases as non-invasive biomarker for detection of bladder cancer

Clinic-pathological parameters

MMP-2

MMP-9

MMP-9/NGAL

MMP-9 dimer

MMP-9/TIMP

ADAMTS

 

(%)

(%)

(%)

(%)

(%)

(%)

Gender

      

    Male

56.3

65.6

62.5

54.2

16.7

25.0

    Female

50.0

55.6

55.6

50.0

0.0

27.8

Age (year)

      

    ≤ 60

47.8

52.2

56.5

47.8

34.8

21.7

    > 60

58.1

67.4

62.8

53.5

20.8

7.0

Tumor size

      

    ≤ 5 cm

52.8

58.3

58.3

52.8

16.7*

13.9

    > 5 cm

58.3

70.8

66.7

50.0

41.7

12.5

Tumor type

      

    TCC

55.6

62.2

60.0

53.3

13.3

22.2

    SCC

52.4

61.9

61.9

52.4

9.5

33.3

Grade

      

    1/2

48.8

58.1

53.3

48.8

16.3

27.9

    3/4

65.0

70.0

75.0

65.0

5.0

20.0

Bilharziasis

      

    Present

59.1

72.7

68.2

45.5

18.2

36.4

    Absent

52.3

56.8

56.8

56.8

9.1

20.5

Lymph nodes

      

    Present

25.0

75.0

75.0

25.0

50.0

50.0

    Absent

52.4

61.9

59.5

54.8

14.5

28.6

Prostatic invasion

      

    Present

60.0

80.0

80.0

60.0

20.0

30.0

    Absent

42.9

50.0

50.0

50.0

14.3

21.4

  1. * Statistically significant.