Table 4 Sensitivity, specificity, accuracy, PPV and NPV for different uMMPs in bladder cancer patients
Markers | Total (%) | MMP-2 (%) | MMP-9 (%) | MMP-9/NGAL (%) | MMP-9 dimers (%) | MMP-9/TIMP (%) | ADAMTS (%) |
|---|---|---|---|---|---|---|---|
Sensitivity | 42/66 | 36/66 | 41/66 | 40/66 | 35/66 | 8/66 | 17/66 |
| Â | (63.6) | (54.5) | (62.1) | (60.9) | (53) | (12.1) | (25.8) |
Specificity | 100/100 | 100/100 | 100/100 | 100/100 | 100/100 | 100/100 | 100/100 |
| Â | (100) | (100) | (100) | (100) | (100) | (100) | (100) |
Accuracy | 142/166 | 136/166 | 141/166 | 140/166 | 135/166 | 108/166 | 125/166 |
| Â | (85.5) | (81.9) | (84.9) | (84.9) | (81.3) | (65) | (70.4) |
PPV | 42/42 | 36/36 | 41/41 | 40/40 | 35/35 | 8/8 | 17/17 |
| Â | (100) | (100) | (100) | (100) | (100) | (100) | (100) |
NPV | 100/124 | 100/130 | 100/125 | 100/126 | 100/131 | 100/158 | 100/149 |
| Â | (80.6) | (76.9) | (80) | (79.4) | (76.3) | (63.3) | (67.1) |