Table 2 Multiadjusted comparison a of sociodemographic, treatment and surgeon characteristics among prostate cancer patients after prostatectomy (n = 1’254) according to surgical margin status
Characteristics | Surgical margin status | Adjusted | P-value | |||
|---|---|---|---|---|---|---|
Odds ratio | ||||||
Positive | Negativeb | |||||
(cases) | (controls) | |||||
N | % | N | % | (95% CI) | ||
Period | ||||||
1990-1994 | 29 | 50.0 | 29 | 50.0 | 1 | 0.025 |
1995-1999 | 105 | 42.9 | 140 | 57.1 | 1.05 (0.53-2.06) | |
2000-2004 | 201 | 40.8 | 292 | 59.2 | 1.47 (0.73-2.99) | |
2005-2008 | 144 | 31.4 | 314 | 68.6 | 0.92 (0.44-1.92) | |
Type of surgery | ||||||
Perineal/Retropubic | 196 | 45.9 | 231 | 54.1 | 1 | 0.443 |
Laparoscopic | 62 | 39.2 | 96 | 60.8 | 0.96 (0.61-1.53) | |
Robot-assisted | 35 | 32.1 | 74 | 67.9 | 0.96 (0.55-1.69) | |
Unknown | 186 | 33.2 | 374 | 66.8 | 0.77 (0.52-1.12) | |
Clinical T | ||||||
cT0-cT1 | 83 | 31.8 | 178 | 68.2 | 1 | 0.038 |
cT2 | 163 | 35.7 | 293 | 64.3 | 0.93 (0.65-1.31) | |
cT3 | 79 | 63.2 | 46 | 36.8 | 1.73* (1.05-2.85) | |
cTx | 154 | 37.4 | 258 | 62.6 | 1.18 (0.82-1.70) | |
Pathological T | ||||||
pT0-pT2 | 239 | 27.5 | 629 | 72.5 | 1 | <0.001 |
pT3-pT4 | 240 | 62.2 | 146 | 37.8 | 2.68 (2.00-3.59) | |
PSA level | ||||||
0-9 | 217 | 32.8 | 445 | 67.2 | 1 | 0.036 |
10-20 | 98 | 51.0 | 94 | 49.0 | 1.52* (1.06-2.17) | |
21+ | 57 | 64.0 | 32 | 36.0 | 1.80* (1.06-3.05) | |
Unknown | 107 | 34.4 | 204 | 65.6 | 1.03 (0.74-1.42) | |
Gleason | ||||||
2-6 | 218 | 30.5 | 497 | 69.5 | 1 | <0.001 |
7 | 195 | 45.2 | 236 | 54.8 | 1.61*** (1.23-2.12) | |
8-10 | 60 | 61.9 | 37 | 38.1 | 2.25*** (1.39-3.63) | |
Unknown | 6 | 54.5 | 5 | 45.5 | 1.87 (0.46-7.71) | |
Tumour percentage c | ||||||
≤10% | 202 | 26.7 | 554 | 73.3 | 1 | <0.001 |
>10% | 252 | 57.9 | 183 | 42.1 | 2.90*** (2.21-3.81) | |
Unknown | 25 | 39.7 | 38 | 60.3 | 1.37 (0.78-2.43) | |
Total | 479 | 38.2 | 775 | 61.8 | ||