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Table 1 Effect of Cecropin A and B on cell viability, proliferation and cytotoxicity

From: Antimicrobial peptides of the Cecropin-family show potent antitumor activity against bladder cancer cells

Cell line

Cell viability

WST-1 IC50 (μg/ml)

Cecropin A/B

Cell proliferation

BrdU IC50 (μg/ml)

Cecropin A/B

Cytotoxicity

LDH IC50 (μg/ml)

Cecropin A/B

ZF07

649.03/732.14

/

/

3T6

/413.92

/

/

486P

251.47/161.76

69.2/87.47

373.3/232.4

RT4

231.26/184.81

96.22/92.9

289.3/240.4

647V

185.39/115.12

28.74/61.86

200.7/181.1

J82

212.07/97.93

99.01/77.51

319.2/196.3

  1. IC50 values were assessed by logarithmic extrapolation; = not assessable or concentration >10,000 μg/ml