Table 3 Study outcomes comparing 5ARI with control
Outcomes | No of studies (Fin/Dut) | No. of patients | RR/MD (Total) | 95%CI (Total) | P value (Fin/Dut/Total) | Heterogeneity (Total) | ||||
|---|---|---|---|---|---|---|---|---|---|---|
5ARI(Fin/Dut) | Control(Fin/Dut) | chi2 | df | I2% | P value | |||||
Blood loss | 7/2 | 272/94 | 276/87 | −73.04 | −107.68,-38.41 | <0.00001/0.24/<0.0001 | 18.31 | 8 | 56 | 0.27 |
Hb alteration | 2/3 | 52/170 | 56/174 | −0.35 | −0.79,0.08 | 0.04/0.76/0.11 | 28.12 | 4 | 86 | <0.0001 |
Blood loss/g tissue | 4/1 | 136/27 | 139/21 | −3.67 | −5.99,-1.36 | 0.008/0.004/0.002 | 27.97 | 4 | 86 | <0.0001 |
MVD | 6/2 | 296/94 | 300/87 | −5.46 | −7.83,-3.09 | <0.00001/0.08/<0.00001 | 675.11 | 7 | 99 | <0.00001 |
VEGF | 6/0 | 373/0 | 373/0 | −67.18 | −89.78,-44.58 | <0.00001 | 499.53 | 5 | 99 | <0.00001 |
Operative time | 6/4 | 252/189 | 256/180 | −3.96 | −8.17,2.87 | 0.12/0.35/0.07 | 32.46 | 9 | 72 | 0.0002 |
Transfusion needed | 4/4 | 94/189 | 102/180 | 0.37 | 0.13,1.02 | 0.17/0.18/0.05 | 0.99 | 6 | 0 | 0.99 |
Gland resected | 7/4 | 254/189 | 262/180 | 1.09 | 0.3,1.87 | 0.01a/0.4/0.006 | 8.46 | 10 | 0 | 0.58 |
Prostate volume | 6/2 | 291/98 | 297/92 | 1.85 | 0.60,3.10 | 0.003a/1.00/0.004 | 4.33 | 7 | 0 | 0.74 |