uPSA | Univariate model | Multivariate model | [−2]proPSA | Univariate model | Multivariate model |
---|---|---|---|---|---|
Covariate | p | p | Covariate | p | p |
Time trend | <0.001 | <0.001 | Time trend | <0.001 | <0.001 |
Age >65 years | 0.095 | 0.455 | Age >65 years | 0.472 | |
BMI >26 | 0.059 | 0.507 | BMI >26 | 0.315 | |
PSA at diagnosis >8 ng/ml | 0.015 | 0.014 | PSA at diagnosis >8 ng/ml | 0.032 | 0.012 |
Positive DRE | 0.168 | Positive DRE | 0.241 | ||
Biopsy samples >5 | 0.365 | Biopsy samples >5 | 0.483 | ||
GS at biopsy >7 | 0.419 | GS at biopsy >7 | 0.349 | ||
MRI lesions >1 | 0.178 | MRI lesions >1 | 0.607 | ||
Prostate volume >40 ml | 0.214 | Prostate volume >40 ml | 0.472 | ||
Tumor percentage >10 % | 0.522 | Tumor percentage >10 % | 0.658 | ||
Positive margins | 0.018 | 0.214 | Positive margins | 0.822 | |
GS at surgery >7 | 0.209 | GS at surgery >7 | 0.102 | ||
Capsule involvement | 0.039 | Capsule involvement | 0.077 | ||
Neural involvement | 0.216 | Neural involvement | 0.603 | ||
Vascular involvement | 0.110 | Vascular involvement | 0.083 | 0.952 | |
pT | <0.001 | 0.038 | pT | 0.008 | 0.879 |
pN | <0.001 | 0.001 | pN | 0.008 | <0.001 |
BCR (uPSA +0,2 ng/ml) | 0.096 | ||||
BCR (3 rising uPSA values) | 0.194 | ||||
pT*pN (interaction) | - | 0.639 | PSA at diagnosis*pN (interaction) | - | 0.099 |