Factors affecting survival and prognosis in surgically treated patients with spinal metastases arising from renal cell carcinoma

Table 2 Univariate and multivariate analysis of Spine Metastasis Free Survival (SMFS).

Factors		Univariate				Multivariate
Factors		Cases	Events	Χ2	p-value	B		HR	95% CI	p-value
Sex	M	38	26	0.436	0.509	NI
Sex	F	11	7	0.436	0.509	NI
Age of RCC	≤ 55	25	17	2.205	0.138	NI
Age of RCC	> 55	24	16	2.205	0.138	NI
Metabolism syndrome	Yes	31	23	0.013	0.911	NI
Metabolism syndrome	No	18	10	0.013	0.911	NI
RCC with visceral metastasis	Yes	23	16	28.4	< 0.001	2.420		11.245	2.824–44.776	0.001
RCC with visceral metastasis	No	26	17	28.4	< 0.001	2.420		11.245	2.824–44.776	0.001
RCC NLR	≤ 2.61	22	13	0.064	0.800	NI
RCC NLR	> 2.61	27	20	0.064	0.800	NI
RCC PLR	≤ 115.26	9	4	0.28	0.597	NI
RCC PLR	> 115.26	40	29	0.28	0.597	NI
RCC HALP	≤ 18.68	7	4	0.58	0.810	NI
RCC HALP	> 18.68	42	29	0.58	0.810	NI
Radical nephrectomy	Yes	25	16	4.377	0.241	NI
Radical nephrectomy	No	24	17	4.377	0.241	NI
AJCC RCC Stage	1,2	17	11	13.164	< 0.001	1.033		2.809	1.046–7.543	0.040
AJCC RCC Stage	3,4	32	22	13.164	< 0.001	1.033		2.809	1.046–7.543	0.040
WHO/ISUP Grade	2	16	10	18.508	< 0.001	0.34	1.045		0.668–2.954	0.37
	3	21	15
	4	12	8

Abbreviations: RCC,Renal cell carcinoma ; NLR,neutrophil-to-lymphocyte ratio; PLR,platelet-to-lymphocyte ratio; HALP,hemoglobin and albumin levels and lymphocyte and platelet counts; AJCC,American Joint Committee on Cancer; WHO,World Health Organization; ISUP,International Society of Urology and Pathology;NI,not included in the multivariate analysis; NS,not significant in the multivariate analysis.

ISSN: 1471-2490