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Table 3 Associations between individual components of MetS and urologic, kidney, prostate, and bladder cancer risk

From: Association of metabolic syndrome and its components with the risk of urologic cancers: a prospective cohort study

Variable

Urologic cancer

Kidney cancer

Prostate cancer

Bladder cancer

HR(95%CI)

HR(95%CI)

HR(95%CI)

HR(95%CI)

BP(mmHg)a

 Normal

Ref

Ref

Ref

Ref

 High

1.35(1.10–1.66)

1.74(1.21–2.51)

1.24(0.83–1.87)

1.13(0.79–1.61)

FBG(mmol/l)b

 Normal

Ref

Ref

Ref

Ref

 High

0.96(0.79–1.16)

1.09(0.79–1.51)

0.89(0.61–1.29)

1.00(0.71–1.40)

HDL-C(mmol/l)c

 Normal

Ref

Ref

Ref

Ref

 Low

0.91(0.74–1.12)

1.37(0.99–1.90)

0.78(0.52–1.17)

0.58(0.39–0.88)

TG(mmol/l)d

 Normal

Ref

Ref

Ref

Ref

 High

1.11(0.92–1.35)

1.22(0.88–1.68)

1.09(0.75–1.58)

1.12(0.79–1.58)

WC(cm)e

 Normal

Ref

Ref

Ref

Ref

 High

1.20(1.00–1.44)

1.19(0.86–1.64)

1.68(1.18–2.40)

0.93(0.67–1.29)

  1. Adjusted for all factors (age, gender, smoking status, alcohol consumption, occupation, education level, income, marital status, salt intake, physical activities, BP, FBG, HDL-C, TG, and WC) excluded itself
  2. MetS metabolic syndrome, BP blood pressure, FBG fasting blood glucose, HDL-C high-density lipoprotein cholesterol, TG triglycerides, WC waist circumference
  3. aHigh was defined as systolic blood pressure ≥ 130 mmHg and/or diastolic blood pressure ≥ 85 mmHg, and/or a history of hypertension treated with antihypertensive drugs. Normal was defined as systolic blood pressure < 130 mmHg and diastolic blood pressure < 85 mmHg
  4. bHigh was defined as FBG ≥ 100 mg/dL (5.6 mmol/L) and/or receiving glucose-lowering medication for elevated glucose. Normal was defined as FBG < 100 mg/dL (5.6 mmol/L)
  5. cLow was defined as HDL-C < 40 mg/dL (1.0 mmol/L) in males and HDL-C < 50 mg/dL (1.3 mmol/L) in females and/or drug treatment for reduced HDL-C.Normal was defined as HDL-C ≥ 40 mg/dL (1.0 mmol/L) in males and HDL-C ≥ 50 mg/dL (1.3 mmol/L) in females and/or drug treatment for reduced HDL-C
  6. dHigh was defined as TG ≥ 150 mg/dL (1.7 mmol/L) and/or drug treatment for elevated TG. Normal was defined as TG < 150 mg/dL (1.7 mmol/L)
  7. eHigh was defined as WC ≥ 90 cm in males and WC ≥ 80 cm in females. Normal was defined as WC < 90 cm in males and WC < 80 cm in females