From: suPARnostic: an advanced predictive tool for detecting recurrence in renal cell carcinoma
Overall Survival | Recurrence Free Survival | ||||||
---|---|---|---|---|---|---|---|
HR | Confidence interval | P value | HR | Confidence interval | P value | ||
suPARnostic (ng/ml) | 0.0500* | 0.00414 | |||||
< 6 | Ref | ||||||
≥ 6 | 1.6893 | 0.9878 to 2.8890 | 1.9147 | 1.0255 to 3.5748 | |||
CRP (mg/L) | 0.0028* | 0.7406 | |||||
≤ 3 | Ref | ||||||
> 3 | 4.2241 | 1.6415 to 10.8696 | 1.1799 | 0.4431 to 3.1419 | |||
Hemoglobin | 0.0219* | 0.7211 | |||||
Normal or higher | Ref | ||||||
Lower than normal | 3.7986 | 1.2134 to 11.8911 | 0.8179 | 0.2712 to 2.4663 | |||
CCI | < 0.0001* | 0.6752 | |||||
0–2 | Ref | ||||||
≥ 3 | 9.7690 | 4.5078 to 21.1708 | 1.2334 | 0.4623 to 3.2907 | |||
Hypertension | 0.1952 | 0.0297 * | |||||
No | Ref | ||||||
yes | 1.5397 | 0.8316 to 2.8508 | 2.3522 | 1.0881 to 5.0847 | |||
Gender | 0.0777* | 0.2428 | |||||
Female | Ref | ||||||
Male | 1.6260 | 0.9475 to 2.7904 | 1.4565 | 0.7749 to 2.7376 | |||
Fuhrman grade | 0.0009* | 0.0236 * | |||||
1–2 | Ref | ||||||
3–4 | 3.4564 | 1.6669 to 7.1672 | 2.4026 | 1.1250 to 5.1313 | |||
T-stage | 0.0022* | < 0.0001* | |||||
T1 | Ref | ||||||
T2 | 2.3203 | 0.8580 to 6.2746 | 2.1881 | 0.6589 to 7.2660 | |||
T3 | 2.7059 | 1.2647 to 5.7894 | 4.9435 | 1.9865 to 12.3018 | |||
Type of surgery | 0.2120 | 0.0998 | |||||
Partial Nephrectomy | Ref | ||||||
Radical Nephrectomy | 2.2837 | 1.3103 to 3.9800 | 1.7046 | 0.9032 to 3.2171 | |||
Symptomatic at RCC recurrence | 0.2450 | 0.4084 | |||||
Asymptomatic | Ref | ||||||
Symptomatic | 1.3701 | 0.8058 to 2.3295 | 0.7703 | 0.4149 to 1.4301 |