Table 2 Multivariable MR analysis between IBD and BC
From: Inflammatory bowel disease and bladder cancer risk: based on a Mendelian randomization study
Exposure | Outcome | No. of SNPs | IVW | LASSO regression | |||||
|---|---|---|---|---|---|---|---|---|---|
Beta | SE | Pvalue | Beta | SE | Pvalue | ||||
Training set | UKBB | ||||||||
CD | BC | 137 | 0.04 | 0.03 | 0.27 | 0.02 | 0.03 | 0.39 | |
UC | -0.05 | 0.04 | 0.24 | -0.02 | 0.04 | 0.55 | |||
Validation set | FinnGen | ||||||||
CD | BC | 132 | -0.05 | 0.04 | 0.22 | -0.03 | 0.04 | 0.32 | |
UC | 0.09 | 0.05 | 0.04 | 0.09 | 0.05 | 0.03 | |||