From: Prediction of biochemical recurrence after laparoscopic radical prostatectomy
Variables | Univariable analysis | Multivariable analysis | |||||
---|---|---|---|---|---|---|---|
HR | 95% Cl | P value | HR | 95% Cl | P value | ||
Initial PSA (ng/mL) | |||||||
<=20 | Ref | Ref | |||||
> 20 | 4.4 | 2.6–7.7 | < 0.001 | 3.2 | 1.8–5.8 | < 0.001 | |
Gleason score | |||||||
6 | Ref | ||||||
7 | 2.7 | 1.5–5.1 | 0.002 | 2.2 | 1.2–3.3 | < 0.001 | |
≥ 8 | 8.4 | 4.3–16.3 | < 0.001 | 5.4 | 2.6–6.8 | < 0.001 | |
Gleason grade group | |||||||
1 | Ref | ||||||
2 | 2.2 | 1.1–4.2 | 0.025 | 1.5 | 0.7–2.9 | 0.29 | |
>=3 | 5.1 | 2.8–9.6 | < 0.001 | 2.2 | 1.1–4.4 | 0.022 | |
Margin status | |||||||
Negative | Ref | Ref | |||||
Positive | 2.6 | 1.8–3.9 | < 0.001 | 1.5 | 1.0-2.3 | 0.046 | |
LVI status | |||||||
Negative | Ref | Ref | |||||
Positive | 2.7 | 1.8–4.1 | < 0.001 | 1.0 | 0.6–1.6 | 0.841 | |
pT stage | |||||||
2 | Ref | Ref | |||||
3a | 3.2 | 1.9–5.4 | < 0.001 | 2.8 | 1.6–4.8 | < 0.001 | |
3b | 8.4 | 5.3–13.3 | < 0.001 | 5.2 | 3.1–8.6 | < 0.001 | |
pN stage | |||||||
0 | Ref | Ref | 0.028 | ||||
1 | 4.8 | 2.6–9.1 | < 0.001 | 3.1 | 1.7–5.8 |