Table 2 Sensitivity, specificity, PPV, NPV, and AUC of different nomograms in predicting lymph node invasion
Cagiannos | 2012-Briganti | MSKCC | Partin | 2018-Briganti | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
Criterion (%) | ≥ 5 | ≥ 5 | ≥ 5 | ≥ 5 | ≥ 7 | |||||
Sensitivity | 72.2 | (46.5; -90.3) | 94.4 | (72.7; 99.9) | 100 | (81.5; 100) | 50 | (26.0; 74.0) | 41.9 | (24.6; 60.9) |
Specificity | 30.2 | (25.2; 35.9) | 59.8 | (53.9; 65.5) | 47.7 | (41.9; 53.7) | 86.9 | (82.5; 90.6) | 51.2 | (35.5; 66.7) |
PPV | 6.0 | (4.6; 7.9) | 12.7 | (10.8; 14.8) | 10.6 | (9.6; 11.7) | 19.2 | (12.0; 29.1) | 38.2 | (27.0; 50.9) |
NPV | 94.7 | (89.1; 97.4) | 99.4 | (96.3; 99.9) | 100 | 96.6 | (94.6; 97.8) | 55.0 | (44.6; 65.0) | |
AUC | 0.512 (0.376; 0.649) | 0.729 (0.496; 0.962) | 0.660 (0.373; 0.946) | 0.424 (0.074; 0.774) | 0.521 (0.112; 0.929) | |||||
Criterion (%) | > 1.5 | > 8.5 | > 1.5 | > 10.5 | > 9.75 | |||||
Sensitivity | 44.4 | (21.5; 69.2) | 75.0 | (34.9; 96.8) | 33.3 | (13.3; 59.0) | 55.6 | (30.8; 78.5) | 50 | (1.3; 98.7) |
Specificity | 93.8 | (90.4; 96.3) | 76.6 | (71.3; 81.4) | 78.7 | (73.5; 83.3) | 47.8 | (41.9; 53.7) | 83.3 | (72.7; 91.1) |
PPV | 30.8 | (18.3; 46.8) | 8.1 | (5.3; 12.2) | 8.8 | (4.6; 16.2) | 6.2 | (4.1; 9.2) | 7.7 | (1.9; 26.8) |
NPV | 96.5 | (94.8; 97.6) | 99.1 | (97.1; 99.7) | 95.0 | (93.2; 96.4) | 94.6 | (91.1; 96.7) | 98.4 | (93.7; 99.6) |
AUC | 0.486 (0.088; 0.884) | 0.550 (0.408;0.692) | 0.517 (0.397; 0.654) | 0.560 (0.417; 0.703) | 0.574 (0.482; 0.666) | |||||
P | 0.189 | 0.116 | 0.112 | 0.370 | 0.599 | |||||