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Table 3 Benefit analysis of systemic lymph node dissections in diagnosing lymph node invasion

From: Benefit and harm of lymphadenectomy in intermediate risk prostate cancer: comparison of five nomograms

 

Cagiannos

2012-Briganti

Partin

MSKCC

2018-Briganti

Criterion (%)

≥ 5

≥ 5

≥ 5

≥ 5

≥ 7

Above threshold

Y

N

Y

N

Y

N

Y

N

Y

N

LNI

8

10

17

1

9

9

18

0

1

1

no LNI

18

273

117

174

38

253

152

139

33

39

RR

8.7

(3.8; 20.1)

22.2

(3.0; 164.7)

5.6

(2.3; 13.3)

30.3

(1.8; 498.2)

1.2

(0.1; 18.1)

NNT

3.7

 

8.3

 

6.4

 

9.6

 

226.7

 

Criterion (%)

> 1.5

> 8.5

> 1.5

> 10.5

> 9.75

Above threshold

Y

N

Y

N

Y

N

Y

N

Y

N

LNI

13

5

6

2

10

8

6

12

1

1

no LNI

203

88

68

223

152

139

62

229

12

60

RR

1.12

(0.41; 3.05)

9.1

(1.9; 44.2)

1.1

(0.5; 2.8)

1.8

(0.7; 4.5)

4.7

(0.3; 70.3)

NNT

155.7

 

13.9

 

136.9

 

26

 

16.5

 
  1. Numbers are absolute values, numbers in parentheses are 95% confidence intervals
  2. MSKCC – Memorial Sloan Kettering Cancer Center; Y – score above criterion threshold; N – score below criterion threshold; LNI – lymph node invasion; RR – relative risk; NNT- number need to treat