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Table 4 Risk analysis of serious complications in systemic lymph node dissections

From: Benefit and harm of lymphadenectomy in intermediate risk prostate cancer: comparison of five nomograms

 

Cagiannos

2012-Briganti

Partin

MSKCC

2018-Briganti

Criterion (%)

≥ 5

≥ 5

≥ 5

≥ 5

≥ 7

Above threshold

Y

N

Y

N

Y

N

Y

N

Y

N

Complication

7

90

46

51

18

79

59

38

13

18

no complications

19

193

88

124

29

183

111

101

21

22

RR

0.85 (0.44;1.63)

1.18 (0.85; 1.64)

1.3 (0.85; 1.91)

1.27 (0.90;1.78)

0.85 (0.49; 1.47)

NNH

-

19.3

12.3

13.6

-

Criterion (%)

> 1.5

> 8.5

> 1.5

> 10.5

> 9.75

Above threshold

Y

N

Y

N

Y

N

Y

N

Y

N

Complications

65

32

22

75

22

52

19

78

6

25

no complications

123

61

52

160

140

95

49

163

7

36

RR

1.01 (0.71; 1.42)

0.93 (0.63; 1.39)

0.38 (0.25; 0.60)

0.86 (0.57; 1.32)

1.13 (0.58; 2.18)

NNH

602.9

-

-

-

19.3

  1. Numbers are absolute values, numbers in parentheses are 95% confidence intervals
  2. MSKCC – Memorial Sloan Kettering Cancer Center; Y – score above criterion threshold; N – score below criterion threshold; RR – relative risk; NNH – number need to harm (data are not shown in case RR < 1, since it indicates a benefit, rather than harm)