Predictive value of systematic immune-inflammation index combined with Ki-67 index on prognosis of prostate cancer patients after laparoscopic radical prostatectomy

Table 1 Clinical baseline characteristics of the enrolled subjects

Parameters	Good prognosis group (N = 235)	Poor prognosis group (N = 55)	P
Age (year)	66.46 ± 5.21	67.53 ± 4.61	0.1637
Hypertension
No	165 (70.21%)	39 (70.91%)	0.6694
Yes	70 (29.79%)	16 (29.09%)	0.6694
Diabetes
No	190 (80.85%)	45 (81.82%)	0.8692
Yes	45 (19.15%)	10 (18.18%)	0.8692
PSA (ng/mL)
< 20	140 (59.57%)	20 (36.36%)	0.0018
≥ 20	95 (40.43%)	35 (63.64%)
Gleason score
< 8	135 (57.45%)	22 (40.00%)	0.0194
≥ 8	100 (42.55%)	33 (60.00%)	0.0194
T stage
T2	109 (46.38%)	16 (29.09%)	0.0197
T3-4	126 (53.62%)	39 (70.91%)	0.0197
Lymph node metastasis
No	144 (61.28%)	25 (45.45%)	0.0322
Yes	91 (38.72%)	30 (54.55%)	0.0322
Seminal vesicle invasion
No	137 (58.30%)	24 (43.64%)	0.0489
Yes	98 (41.70%)	31 (56.36%)	0.0489
Neutrophils (×10⁹/L)	3.31 (1.24,5.21)	3.62 (2.28,5.48)	0.0166
Lymphocytes (×10⁹/L)	1.84 (0.80,3.25)	1.45 (0.82,2.41)	< 0.0001
Platelets (×10⁹/L)	229 (163,355)	284 (207,332)	< 0.0001
Preoperative SII	423.70 (117.10,1197)	692.10 (275.7,1275)	< 0.0001
Ki-67 index	13.84 ± 2.47	18.14 ± 3.38	< 0.0001

Note: Counting data were expressed by number of cases and percentages, and Chi-square test was used for comparisons among groups. The age conformed to the normal distribution, expressed as mean ± standard deviation, and tested by the independent sample t test; the neutrophil count, lymphocyte count, platelets, and preoperative SII conformed to the non-normal distribution, expressed as median (minimum, maximum), and tested by Mann-Whitney U test. Ki-67 index conformed to normal distribution was expressed as mean ± standard deviation and tested by independent sample t test

ISSN: 1471-2490