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Table 1 Clinicopathological characteristics of elderly patients with PC

From: Prognostic significance of surgery and radiotherapy in elderly patients with localized prostate cancer: establishing and time-based external validation a nomogram from SEER-based study

 

All

Training cohort

Validation cohort

p

N = 90,434

N = 63,328

N = 27,106

Age

71.4 (5.29)

71.4 (5.28)

71.4 (5.33)

0.765

Race:

   

0.460

 white

70,848 (78.3%)

49,670 (78.4%)

21,178 (78.1%)

 

 black

11,557 (12.8%)

8082 (12.8%)

3475 (12.8%)

 

 other

8029 (8.9%)

5576 (8.8%)

2453 (9.1%)

 

Marital:

   

0.150

 No

29,277 (32.4%)

20,595 (32.5%)

8682 (32.0%)

 

 Married

61,157 (67.6%)

42,733 (67.5%)

18,424 (68.0%)

 

Grade:

   

0.096

 I

17,153 (18.97%)

11,990 (18.93%)

5163 (19.05%)

 

 II

40,450 (44.73%)

28,459 (44.94%)

11,991 (44.25%)

 

 III

32,798 (36.27%)

22,852 (36.09%)

9946 (36.69%)

 

 IV

33 (0.03%)

27 (0.04%)

6 (0.01%)

 

T:

   

0.995

 T1a-b

2900 (3.2%)

2036 (3.2%)

864 (3.2%)

 

 T1c

54,981 (60.8%)

38,488 (60.8%)

16,493 (60.8%)

 

 T2a-b

13,055 (14.4%)

9145 (14.4%)

3910 (14.5%)

 

 T2c

19,498 (21.6%)

13,659 (21.6%)

5839 (21.5%)

 

Surgery:

   

0.410

 No

66,237 (73.2%)

46,465 (73.4%)

19,772 (72.9%)

 

 Local tumor resection

5209 (5.8%)

3631 (5.7%)

1578 (5.9%)

 

 Radical prostatectomy

18,988 (21.0%)

13,232 (20.9%)

5756 (21.2%)

 

Chemotherapy:

   

0.611

 No

90,262 (99.8%)

63,204 (99.8%)

27,058 (99.8%)

 

 Yes

172 (0.2%)

124 (0.2%)

48 (0.2%)

 

Radiation:

   

0.840

 No

50,159 (55.5%)

35,089 (55.4%)

15,070 (55.6%)

 

 Beam radiation

30,763 (34.0%)

21,596 (34.1%)

9167 (33.8%)

 

 Radioactive implants or isotopes

5549 (6.1%)

3868 (6.1%)

1681 (6.2%)

 

 Combination

3963 (4.4%)

2775 (4.4%)

1188 (4.4%)

 

Gleason:

   

0.548

  ≤ 6

33,137 (36.6%)

23,195 (36.6%)

9942 (36.7%)

 

 7

40,277 (44.5%)

28,266 (44.6%)

12,011 (44.3%)

 

  ≥ 8

17,020 (18.9%)

11,867 (18.8%)

5153 (19.0%)

 

PSA:

   

0.369

 <10

64,984 (71.9%)

45,455 (71.8%)

19,529 (72.0%)

 

 10–20

17,569 (19.4%)

12,377 (19.5%)

5192 (19.2%)

 

 >20

7881 (8.7%)

5496 (8.7%)

2385 (8.8%)

 

CSS:

   

0.194

 Dead

1911 (2.1%)

1312 (2.1%)

599 (2.2%)

 

 Alive

88,523 (97.9%)

62,016 (97.9%)

26,507 (97.8%)

 

OS:

   

0.871

 Dead

9584 (10.6%)

6704 (10.6%)

2880 (10.6%)

 

 Alive

80,850 (89.4%)

56,624 (89.4%)

24,226 (89.4%)

 

Survival.months

48.7 (29.1)

48.6 (29.1)

48.9 (29.2)

0.194

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