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Table 2 Univariate and multivariate analyses of CSS in training cohort

From: Prognostic significance of surgery and radiotherapy in elderly patients with localized prostate cancer: establishing and time-based external validation a nomogram from SEER-based study

 

Univariate

Multivariate

HR

95%CI

P

HR

95%CI

P

Age

1.14

1.13–1.14

< 0.001

1.057

1.048–1.067

< 0.001

Race

      

 white

      

 black

1.33

1.14–1.54

< 0.001

1.149

0.986–1.339

0.075

 other

0.76

0.62–0.93

0.009

0.616

0.5–0.76

< 0.001

Marital

      

 No

      

 Married

0.6

0.54–0.67

< 0.001

0.768

0.688–0.857

< 0.001

Grade

      

 I

      

 II

1.39

1.05–1.84

0.023

   

 III

3.99

3.05–5.22

< 0.001

   

 IV

6.01

1.47–24.62

0.013

   

T

      

 T1a-b

      

 T1c

0.35

0.28–0.42

< 0.001

0.722

0.541–0.964

0.027

 T2a-b

0.31

0.25–0.4

< 0.001

0.767

0.558–1.053

0.101

 T2c

0.21

0.17–0.26

< 0.001

1.087

0.783–1.507

0.619

Surgery

      

No

      

 Local tumor excision

2.45

2.11–2.86

< 0.001

1.39

1.111–1.737

0.004

 Radical prostatectomy

0.23

0.18–0.29

< 0.001

0.177

0.134–0.235

< 0.001

Chemotherapy

      

 No

      

 Yes

2.96

1.41–6.22

0.004

   

Radiation

      

No

      

 Beam radiation

0.95

0.85–1.07

0.374

0.468

0.412–0.531

< 0.001

 Radioactive implants or isotopes

0.46

0.35–0.62

< 0.001

0.458

0.341–0.616

< 0.001

 Combination

0.84

0.64–1.1

0.204

0.422

0.319–0.557

< 0.001

PSA

      

 <10

      

 10–20

2.27

1.99–2.59

< 0.001

1.455

1.27–1.668

< 0.001

 >20

6.8

6–7.72

< 0.001

2.431

2.111–2.8

< 0.001

Gleason

      

  ≤ 6

      

 7

1.95

1.66–2.29

< 0.001

2.158

1.824–2.553

< 0.001

  ≥ 8

8.19

7.04–9.53

< 0.001

6.191

5.217–7.348

< 0.001