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Table 3 Univariate and multivariate analyses of OS in training cohort

From: Prognostic significance of surgery and radiotherapy in elderly patients with localized prostate cancer: establishing and time-based external validation a nomogram from SEER-based study

 

Univariate

Multivariate

HR

95%CI

P

HR

95%CI

P

Age

1.11

1.11–1.11

< 0.001

1.072

1.067–1.076

< 0.001

Race

      

 white

      

 black

1.35

1.27–1.45

< 0.001

1.289

1.204–1.38

< 0.001

 other

0.73

0.66–0.8

< 0.001

0.654

0.595–0.72

< 0.001

Marital

      

 No

      

 Married

0.64

0.61–0.67

< 0.001

0.753

0.716–0.791

< 0.001

Grade

      

 I

      

 II

1.09

0.99–1.2

0.081

   

 III

1.73

1.57–1.9

< 0.001

   

 IV

1.26

0.47–3.38

0.642

   

T

      

 T1a-b

      

 T1c

0.43

0.39–0.48

< 0.001

   

 T2a-b

0.38

0.34–0.43

< 0.001

   

 T2c

0.24

0.22–0.27

< 0.001

   

Surgery

      

No

      

 Local tumor excision

1.85

1.72–2

< 0.001

1.108

0.982–1.25

0.097

 Radical prostatectomy

0.35

0.32–0.38

< 0.001

0.35

0.31–0.395

< 0.001

Chemotherapy

      

 No

      

 Yes

1.79

1.17–2.75

0.007

   

Radiation

      

No

      

 Beam radiation

1.09

1.04–1.15

0.001

0.691

0.652–0.733

< 0.001

 Radioactive implants or isotopes

0.72

0.64–0.8

< 0.001

0.658

0.588–0.736

< 0.001

 Combination

0.87

0.77–0.98

0.022

0.583

0.513–0.663

< 0.001

PSA

      

 <10

      

 10–20

1.66

1.57–1.76

< 0.001

1.236

1.165–1.313

< 0.001

 >20

3.07

2.87–3.28

< 0.001

1.592

1.481–1.71

< 0.001

Gleason

      

  ≤ 6

      

 7

1.37

1.3–1.46

< 0.001

1.313

1.209–1.427

< 0.001

  ≥ 8

2.69

2.53–2.86

< 0.001

1.869

1.678–2.081

< 0.001