Skip to main content

Table 1 Comparison of baseline characteristics and infectious complications between patients who received fosfomycin and those who received flumarin for antimicrobial prophylaxis for TRUS guided prostate biopsy

From: Efficacy of fosfomycin compared to second generation cephalosporin flumarin as antimicrobial prophylaxis for transrectal ultrasound-guided prostate biopsy: a single center retrospective study

 

Fosfomycin

Flumarin

p

n

333

2567

 

Age

68.3 ± 8.8

67.5 ± 8.7

0.1611

DM

54 (16.2%)

405 (15.8%)

0.8362

Health care risk*

8 (2.4%)

120 (4.7%)

0.0582

Operation < 6 months

6 (1.8%)

47 (1.8%)

0.9702

UTI < 6 months

4 (1.2%)

18 (0.7%)

0.3083

Prior prostate biopsy

17 (5.1%)

344 (13.4%)

0.0002

Prior antibiotics < 6 months

57 (17.1%)

503 (29.6%)

0.2652

PSA Group

  

0.2612

 < 10

196 (58.9%)

1566 (61.0%)

 

 10–20

66 (19.8%)

547 (21.3%)

 

 > 20

71 (21.3%)

454 (17.7%)

 

Prostate size

44.5 ± 20.9

44.9 ± 20.8

0.7891

No of biopsy cores

11.4 ± 1.8

10.8 ± 2.0

0.0001

Cancer detection

146 (43.8%)

887 (34.6%)

0.0012

Infectious complications (overall)

19 (5.7%)

220 (8.6%)

0.0742

Infectious complications (hospitalization)

3 (0.9%)

8 (0.3%)

0.0732

  1. DM = diabetes mellitus, UTI = urinary tract infection, FQ = fluoroquinolone, PSA = prostate specific antigen
  2. *Health care risk = admission within 90 days, urethral catheterization within 30 days, invasive urologic procedures within 30 days, dialysis, chemotherapy
  3. 1Mann Whitney U test
  4. 2Chi square test
  5. 3Fisher’s exact test