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Fig. 4 | BMC Urology

Fig. 4

From: De-obstruction of bladder outlet in humans reverses organ remodelling by normalizing the expression of key transcription factors

Fig. 4

Gene Ontology Over-Representation Analysis of regulated mRNAs in MP group before and after de-obstruction. A and B treemap views of GO-term clusters (Biological processes, BPs), where each tile and colour represent a term and cluster, respectively. The list of GO terms was converted into a semantic similarity matrix using binary cut method. Tile size and group representatives of each cluster are corresponding to the GO terms’ size. C and D Word clouds of up-regulated (in red) and down-regulated (in blue) mRNAs, font size corresponding to the frequency of appearance in GO BPs. E and F Ridge plots of GO ORA showing average Log2FC of the main enriched genes. AC and E treemap, word cloud and ridge plot for MP group before_MP vs. control DEGs, B, D and F treemap, word cloud and ridge plot for MP group after_MP vs. control DEGs

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