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Fig. 6 | BMC Urology

Fig. 6

From: De-obstruction of bladder outlet in humans reverses organ remodelling by normalizing the expression of key transcription factors

Fig. 6

Gene Ontology Over-Representation Analysis and IPA pathway analysis of regulated proteins in HP and MP BPO groups before and after de-obstruction Treemap views of GO-term clusters (Biological processes, BPs) for DEPs in HP group before (A) and after (B) deobstruction, compared to controls. Word clouds of up-regulated (in red) and down-regulated (in blue) proteins, font size corresponding to the frequency of appearance in GO BPs. Top canonical IPA pathways with non-zero z-score for HP before TURP samples (C) and HP after TURP samples (D) compared to controls. Treemap views of GO-term clusters (Biological processes, BPs) for DEPs in MP group before (E) and after (F) de-obstruction, compared to controls. Word clouds of up-regulated (in red) and down-regulated (in blue) proteins, font size corresponding to the frequency of appearance in GO BPs. Top canonical IPA pathways with non-zero z-scores for MP before TURP samples (G) and MP after TURP samples (H) compared to controls

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BMC Urology

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