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Table 1 Characteristics of included studies

From: The association between hepatitis B virus and semen quality: a systematic review and meta-analysis

Study

Year published

Country

Study design

Use of ART

Recruitment Period

HBV(+) group

Control group

Outcome

Guidelines for semen analysis

Newcaste-Ottawa score

Patients

Age (years)

Patients

Age (years)

Bu et al. [17]

2014

China

cohort study

Yes

2010–2012

20

36.7 ± 7.2

257

36 ± 7.4

semen volume, sperm concentration, motility, progressive motility rate, morphology

Unclear

Medium (6 points)

F. Lorusso et al. [10]

2009

Italy

Case control

Yes

2004–2008

30

36.9 ± 6.1

130

36 ± 4.1

semen volume, sperm concentration, progressive motility rate, morphology

WHO 1999

Low (5 points)

G. Cito et al. [18]

2019

Italy

cohort study

Yes

2011–2018

66

36.7 ± 6.5

68

38.7 ± 4.4

semen volume, total sperm count, sperm concentration, progressive motility rate, morphology

WHO 2010

High (8 points)

Karamolahi et al. [20]

2019

Iran

Case control

Unclear

2003–2014

112

36.7 ± 7.5

112

34.4 ± 7.8

semen volume, total sperm count, sperm motility, morphology,

WHO 1999

High (8 points)

P. Oger et al. [21]

2011

France

Case control

Yes

2005–2008

32

34.7 ± 5.0

64

35.3 ± 6.3

sperm concentration, progressive motility rate, morphology, motility

WHO 1992

Medium (7 points)

Qian et al. [22]

2016

China

Case control

Unclear

2015–2015

30

30

semen volume, sperm concentration, progressive motility rate, motility, morphology

Unclear

Medium (6 points)

Shi et al. [23]

2014

China

Case control

Yes

2008–2012

136

32.9 ± 4.7

272

32.6 ± 5.0

sperm concentration, progressive motility rate, morphology

WHO 2010

Medium (7 points)

VCY Lee et al. [24]

2010

China

Case control

Yes

2004–2008

154

1473

sperm concentration, progressive motility rate, morphology

Unclear

Medium (6 points)

Wang et al. [25]

2021

China

Case control

Yes

2016–2020

227

34.8 ± 4.9

454

34.7 ± 4.7

semen volume, sperm concentration, progressive motility rate, morphology

WHO 1999

High (8 points)

Yakass, M.B et al. [19]

2016

Ghana

cohort study

Yes

2013–2015

27

196

sperm concentration, progressive motility rate, morphology

WHO 2010

Medium (6 points)

Zhou et al. [26]

2011

China

Case control

Yes

2008–2009

457

33.4 ± 4.8

459

33.5 ± 4.8

semen volume, total sperm count, sperm concentration, progressive motility rate, morphology

WHO 1999

High (8 points)