Table 2 Univariate and multivariate analyses of factors associated with primary NMIBC recurrence

Age

≤ 82 vs. > 82

3.94 (2.04–7.60)

P < 0.001***

2.33 (1.07–5.09)

0.0330*

Gender

Male vs. Female

1.26 (0.75–2.12)

0.385

-

Urinary leucocyte counts (/uL)

≤ 3.96 vs. > 3.96

3.25 (1.84–5.76)

P < 0.001***

2.32 (1.26–4.32)

0.0073**

Urinary bacterium (/uL)

≤ 202 vs. > 202

1.88 (1.11–3.16)

0.0184*

1.53 (0.80–2.89)

0.1964

Urinary mucus filament (/uL)

≤ 178 vs. > 178

0.38 (0.24–0.61)

P < 0.001***

0.42 (0.25–0.69)

0.0006***

Urinary nitrite

Negative vs. Positive

1.03 (0.57–1.87)

0.92

-

Urinary protein

Negative

-

-

-

+

0.98 (0.62–1.55)

0.9277

0.92 (0.54–1.55)

0.7497

++

2.25 (1.20–4.22)

0.0112*

1.50 (0.73–3.06)

0.2607

T-stage

Ta vs. T1

1.18 (0.75–1.86)

0.465

-

-

Tumor size (cm)

≤ 3 vs. > 3

1.45 (0.93–2.26)

0.1

-

-

Tumor grade

Low vs. High

1.22 (0.76–1.98)

0.402

-

-

Tumor numbers

Single vs. Multiple

1.37 (0.89–2.07)

0.145

-

-

Non-pedicled tumor

No vs. Yes

1.33 (0.86–2.06)

0.199

-

-

Hemoglobin (g/L)

≤ 134 vs. > 134

0.73 (0.47–1.16)

0.192

-

-

Albumin (g/L)

≤ 37.5 vs. > 37.5

0.36 (0.18–0.72)

0.0041**

0.76 (0.35–1.71)

0.5177

Lymphocyte (10⁹/L)

≤ 1.66 vs. > 1.66

0.69 (0.43–1.10)

0.123

-

-

Platelet (10⁹/L)

≤ 200 vs. > 200

1.76 (1.11–2.78)

0.0154*

1.70 (1.04–2.78)

0.0337*

HALP

≤ 35.26 vs. > 35.26

0.44 (0.24–0.78)

0.0056**

0.72 (0.37–1.39)

0.3358