Table 2 Results of subgroup analysis of the association between B7-H3 expression and clinicopathological parameters
Outcome of interest | Studies(n) | Patients | OR (95%CI) | P value | Model | Heterogeneity | |
|---|---|---|---|---|---|---|---|
| Â | Â | Â | Â | Â | Â | I2(%) | P value |
Age (≥ 65 vs. <65 years) | 3 | 325 | 2.09(1.29,3.39) | 0.003 | Fixed | 0 | 0.99 |
Gender (Male vs. Female) | 6 | 753 | 0.78(0.52,1.19) | 0.25 | Fixed | 0 | 0.56 |
Tumor grade (low vs. high) | 4 | 370 | 1.50(0.90,2.52) | 0.12 | Fixed | 0 | 0.7 |
LN metastasis (Positive vs. negative) | 5 | 708 | 1.20(0.85,1.68) | 0.3 | Fixed | 26 | 0.25 |
Depth of infiltration | Â | Â | Â | Â | Â | Â | Â |
 Ta-2 vs. T3-4 | 5 | 708 | 0.63(0.45,0.88) | 0.007 | Fixed | 10 | 0.35 |
 NMIBC vs. MIBC | 5 | 869 | 1.03(0.57,1.83) | 0.93 | Random | 51 | 0.09 |
 NMIBC (Ta/Tis vs. T1) | 2 | 590 | 1.83(0.27,12.33) | 0.54 | Random | 69 | 0.07 |
 MIBC (T2 vs. T3-4) | 4 | 555 | 0.62(0.42,0.92) | 0.02 | Fixed | 0 | 0.57 |
Recurrence vs. No recurrence | 4 | 880 | 2.21(1.67,2.92) | < 0.00001 | Fixed | 11 | 0.34 |