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Table 3 Accuracy of the prediction score of the nomogram for estimating the risk of false-positive lesions

From: Prediction of false-positive PI-RADS 5 lesions on prostate multiparametric MRI: development and internal validation of a clinical-radiological characteristics based nomogram

 

Value (95% CI)

 

Variable

Training Cohort

Validation Cohort

Lesion area under ROC curve, concordance index

0.821 (0.762–0.880)

0.871 (0.794–0.947)

Cutoff value

0.290

0.288

Sensitivity, %

81.6 (72.9–90.3)

90.6 (80.5–100)

Specificity, %

68.9 (61.0-76.8)

67.9 (55.6–80.1)

Positive predictive value, %

60.2 (50.7–69.6)

61.7 (47.8–75.6)

Negative predictive value, %

86.7 (80.2–93.2)

92.7 (84.7–100)

Positive likelihood ratio

2.626 (1.994–3.460)

2.819 (1.896–4.192)

Negative likelihood ratio

0.867 (0.802–0.932)

0.138 (0.046–0.412)

  1. ROC: receiver operating characteristic