Mendelian randomization study supports positive bidirectional causal relationships between genetically predicted insomnia symptom and liability to benign prostatic hyperplasia

Table 3 Assessment of horizontal pleiotropy by MR-Egger intercept test and MR-PRESSO global test

Exposure	Outcome	MR-Egger intercept test			MR-PRESSO global test
Exposure	Outcome	Intercept	SE	P - value	RSS obs	P - value
Insomnia	Hyperplasia of prostate	-9.57E-04	0.013	0.942	23.472	0.059
Hyperplasia of prostate	Insomnia	9.51E-04	0.004	0.810	32.620	0.591

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