From: Efficacy and safety of solifenacin combined with biofeedback in children with overactive bladder
Group A | Group B | Group C | ||||
---|---|---|---|---|---|---|
UI group n = 8 | Non-UI group n = 7 | UI group n = 7 | Non-UI group n = 8 | UI group n = 8 | Non-UI group n = 7 | |
Before treatment | ||||||
The median voiding frequency per day (times) | 13 | 13 | 13 | 12 | 15 | 12 |
Median functional bladder capacity (ml) | 120 | 130 | 130 | 140 | 130 | 120 |
Increased Qmax | 75.0% (6/8) | 85.7% (6/7) | 71.4% (5/7) | 75.0% (6/8) | 75.0% (6/8) | 85.7% (6/7) |
Increased bladder sensation | 100% (8/8) | 100% (7/7) | 100% (7/7) | 100% (8/8) | 100% (8/8) | 100% (7/7) |
Decreased bladder compliance | 62.5% (5/8) | 42.9% (3/7) | 71.4% (5/7) | 50.0% (4/8) | 62.5% (5/8) | 42.9% (3/7) |
Detrusor instability | 50.0% (4/8) | 28.6% (2/7) | 71.4% (5/7) | 25.0% (2/8) | 62.5% (5/8) | 28.6% (2/7) |
At 2 weeks | ||||||
The complete response rates | 37.5% (3/8) | 28.6% (2/7) | 28.6% (2/7) | 12.5% (1/8) | 67.5% (5/8) | 42.9% (3/7) |
The partial response rates | 37.5% (3/8) | 28.6% (2/7) | 28.6% (2/7) | 25.0% (2/8) | 25.0% (2/8) | 28.6% (2/7) |
The median voiding frequency per day (times) | 10 | 10 | 11 | 10 | 11 | 9 |
Median functional bladder capacity (ml) | 150 | 140 | 150 | 150 | 160 | 150 |
At 4 weeks | ||||||
The complete response rates | 50.0% (4/8) | 42.9% (3/7) | 42.9% (3/7) | 25.0% (2/8) | 75.0% (6/8) | 42.9% (3/7) |
The partial response rates | 25.0% (2/8) | 28.6% (2/7) | 28.6% (2/7) | 37.5% (3/8) | 12.5% (1/8) | 42.9% (3/7) |
The median voiding frequency per day (times) | 10 | 9 | 10 | 10 | 8 | 7 |
Median functional bladder capacity (ml) | 160 | 160 | 160 | 160 | 180 | 170 |
At 8 weeks | ||||||
The complete response rates | 50.0% (4/8) | 57.1% (4/7) | 42.9% (3/7) | 37.5% (3/8) | 75.0% (6/8) | 57.1% (4/7) |
The partial response rates | 37.5% (3/8) | 28.6% (2/7) | 42.9% (3/7) | 37.5% (3/8) | 25.0% (2/8) | 28.6% (2/7) |
The median voiding frequency per day (times) | 8 | 8 | 9 | 9 | 6 | 6 |
Median functional bladder capacity (ml) | 180 | 170 | 170 | 160 | 210 | 190 |
At 12 weeks | ||||||
The complete response rates | 75.5% (6/8) | 57.1% (4/7) | 71.4% (5/7) | 50.0% (4/8) | 87.5% (7/8) | 85.7% (6/7) |
The partial response rates | 12.5% (1/8) | 42.9% (3/7) | 14.3% (1/7) | 25.0% (2/8) | 12.5% (1/8) | 14.3% (1/7) |
The median voiding frequency per day (times) | 6 | 7 | 7 | 8 | 5 | 6 |
Median functional bladder capacity (ml) | 200 | 190 | 190 | 180 | 240 | 220 |
Increased Qmax | 25.0% (2/8) | 28.6% (2/7) | 28.6% (2/7) | 25.0% (2/8) | 12.5% (1/8) | 14.3% (1/7) |
Increased bladder sensation | 25.0% (2/8) | 28.6% (2/7) | 42.9% (3/7) | 37.5% (3/8) | 25.0% (2/8) | 14.3% (1/7) |
Decreased bladder compliance | 12.5% (1/8) | 14.3% (1/7) | 28.6% (2/7) | 25.0% (2/8) | 0 | 14.3% (1/7) |
Detrusor instability | 0 | 0 | 14.3% (1/7) | 12.5% (1/8) | 0 | 0 |