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Table 1 Association of different patient and tumor specific characteristics with CAV1 protein expression in the tumor cytoplasm.

From: Caveolin 1 protein expression in renal cell carcinoma predicts survival

Variable

CAV1 in tumor cytoplasm ≤ median

CAV1 in tumor cytoplasm > median

p-value

Test

Age (mean; ± SD)

60.4 ± 11.5 years

59.3 ± 11.1 years

0.40

t-test

Sex

  

0.04

Fisher's exact

   female

79 (50.6%)

51 (38.3%)

  

   male

77 (49.4%)

82 (61.7%)

  

Stage (TNM 2002)

  

0.54

Chi2

   pT1

5 (3.2%)

3 (2.3%)

  

   pT2

86 (55.1%)

64 (48.1%)

  

   pT3

58 (37.2%)

57 (42.9%)

  

   pT4

7 (4.5%)

9 (6.7%)

  

LN metastasis1

  

0.04

Fisher's exact

   pN0

78 (89.7%)

70 (77.8%)

  

   pN+

9 (10.3%)

20 (22.2%)

  

Pulmonal/visceral metastasis1

  

0.23

Fisher's exact

   M0

124 (82.7%)

93 (76.2%)

  

   M+

26 (17.3%)

29 (23.8%)

  

Grade

  

0.04

Chi2

   G1

30 (21.6%)

20 (17.7%)

  

   G2

103 (74.1%)

78 (69.0%)

  

   G3/4

6 (4.3%)

15 (13.3%)

  
  1. 1 at time of renal surgery.
  2. Abbreviations: CAV1 = caveolin 1, RCC = renal cell carcinoma, SD = standard deviation, LN = lymph node.