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  2. Germline mutations represent a high risk of hereditary cancers in population. The landscape and characteristics of germline mutations in genitourinary cancer are largely unknown, and their correlation with pat...

    Authors: Yong Yang, Guoying Zhang, Chen Hu, Wei Luo, Haiyang Jiang, Shaoyou Liu and Hong Yang
    Citation: BMC Urology 2022 22:196
    Content type: Research Published on:

  3. Unpredicted postoperative recurrence of prostate cancer, one of the most common malignancies among males worldwide, has become a prominent issue affecting patients after treatment. Here, we investigated the co...

    Authors: Wenyan He, Furong Zhang, Feng Jiang, Huan Liu and Gang Wang
    Citation: BMC Urology 2022 22:195
    Content type: Research Published on:

  4. Noninvasively urine-based diagnostic modalities for upper urinary tract urothelial carcinoma (UTUC) were still lacking. We evaluated the diagnostic value of our previously developed urine-based assay (UTC assa...

    Authors: Xin Wang, Shiwei Zhang, Lang Wu, Baofu Feng, Hongwei Shen, Yuanyuan Gu, Qun Zhang, Feng Fang, Rong Yang and Hongqian Guo
    Citation: BMC Urology 2022 22:194
    Content type: Research Published on:

  6. To evaluate the incidence of positive cystic fluid cytology and its risk factors in cystic renal cell carcinoma (RCC) addressing its implication on the current surgical practice.

    Authors: Kyung Jae Hur, Qais Hooti, Dongho Shin, Yong Hyun Park, Woong Jin Bae, Hyukjin Cho, U-syn Ha, Ji Youl Lee, Yeong Jin Choi and Sung-Hoo Hong
    Citation: BMC Urology 2022 22:192
    Content type: Research Published on:

  7. More and more evidence showed that circRNA/miRNA/mRNA axis played a vital role in the pathogenesis of some diseases. However, the role of circRNA/miRNA/mRNA axis in partial bladder outlet obstruction (pBOO) re...

    Authors: Baoyi Zhu, Jun Gao, Yuying Zhang, Baojian Liao, Sihua Zhu, Chunling Li, Junhao Liao, Jianjia Liu, Chonghe Jiang and Jianwen Zeng
    Citation: BMC Urology 2022 22:191
    Content type: Research Published on:

  8. Hyperglycinuria is a rare disorder, with few reported cases, caused by either a defect in glycine metabolism or a disturbance in renal glycine reabsorption. Genetic findings of hyperglycinuria are rare and hav...

    Authors: Yang Pan, Shangren Wang, Li Liu and Xiaoqiang Liu
    Citation: BMC Urology 2022 22:190
    Content type: Case report Published on:

  9. The high recurrence rate after traditional transurethral resection of bladder tumor (TURBT) remains a challenge for management of non-muscle invasive bladder tumor (NMIBC). The aim of this study was to evaluat...

    Authors: Lichen Teng, Changfu Li, Wentao Wang and Dechao Li
    Citation: BMC Urology 2022 22:189
    Content type: Research Published on:

  10. Urinary tract infections are among the most common indications for antibiotic therapy. The emergence of resistant uropathogens indicates the need for treatment alternatives. Replenishment of the glycosaminogly...

    Authors: M. S. Rahnama’i, A. Javan Balegh Marand, K. Röschmann-Doose, L. Steffens and H. J. Arendsen
    Citation: BMC Urology 2022 22:188
    Content type: Research Published on:

  11. Most patients with splenosis have no clinical symptoms and do not need intervention. Hematospermia and testicular pain occurred in this patient, which was considered to be related to the huge pelvic implantati...

    Authors: Yu Jiang, Lei Chen, Min Wang, Xiaocan Li, Dongdong Xie, Dexin Yu and Yi Wang
    Citation: BMC Urology 2022 22:187
    Content type: Case report Published on:

  12. Soft tumors of the penis are extremely rare in childhood and adolescence. Because there are no guidelines, each such case raises embarrassment over the extent and degree of aggressiveness of the diagnostic and...

    Authors: Marcel Drlík, Mária Gregová, Josef Sedláček and Radim Kočvara
    Citation: BMC Urology 2022 22:186
    Content type: Case report Published on:

  13. The American Joint Committee on Cancer (AJCC) 8th staging system of prostate cancer may be insufficient in predicting the prognosis of some staged patients. This study aimed to modify the AJCC 8th staging syst...

    Authors: Chengwen Sun, Dongrong Yang, Jin Zhu, Yibin Zhou, Congming Xiang and Sheng Wu
    Citation: BMC Urology 2022 22:185
    Content type: Research Published on:

  14. Despite the generally accepted World Health Organization guidelines on semen analysis, an individual’s results can display significant variation when performed across time or in different laboratories. Semen p...

    Authors: Yana Aznavour, Felipe Navarrete, Jad Badreddine, Paul H. G. Simon, Vrushab Gowda, Stephen Rhodes and Ramy Abou Ghayda
    Citation: BMC Urology 2022 22:184
    Content type: Research Published on:

  16. In this study, we investigated the ability of prostate-specific antigen (PSA) 12 months after (nPSA12) external beam radiotherapy (EBRT) combined with androgen deprivation therapy (ADT) to predict biochemical ...

    Authors: Ilknur Alsan Cetin, Sıtkı Utku Akay and Meric Sengoz
    Citation: BMC Urology 2022 22:182
    Content type: Research Published on:

  17. This study aimed to identify and validate the information content and functional capabilities of a smartphone-based application for the self-care of patients with urinary tract stones.

    Authors: Leila Shahmoradi, Amin Azizpour, Mahmud Bejani, Pejman Shadpour, Sorayya Rezayi, Jebraeil Farzi and Alireza Amanollahi
    Citation: BMC Urology 2022 22:181
    Content type: Research Published on:

  18. The retrospective observational study aimed to evaluate the safety and efficacy of suctioning flexible ureteroscopy with Intelligent pressure-control (SFUI) on treating upper urinary tract calculi in a large c...

    Authors: Xingjian Gao, Zedong Zhang, Xinwei Li, Weiping Cai, Bin Zheng, Yijin Lu, Hualong Zhao, Junhong You, Gangfeng Zheng, Weilong Bao, Yutong Lai and Yisong Lv
    Citation: BMC Urology 2022 22:180
    Content type: Research Published on:

  19. Situs inversus totalis is a very rare congenital anatomical variation, in which all thoracic and abdominal organs are right-left inverted. This condition is associated with an increased risk of organ malformat...

    Authors: Marah Mansour, Abdulmonem Naksho, Yassamine Ouerdane, Tamim Alsuliman, Hani Almozawer and Khaled Alrebdawi
    Citation: BMC Urology 2022 22:179
    Content type: Case report Published on:

  20. Lower urinary tract symptoms (LUTS) are common among diabetic patients and represent hidden and mysterious morbidity. The pathophysiology of LUTS among diabetes mellitus (DM) patients is multifactorial. Import...

    Authors: Hala Qasrawi, Mahmoud Tabouni, Sara W. Almansour, Mohammad Ghannam, Amjad Abdalhaq, Faris Abushamma, Amer A. Koni and Sa’ed H. Zyoud
    Citation: BMC Urology 2022 22:178
    Content type: Research Published on:

  21. While gemcitabine/cisplatin (GC) is the gold standard regimen for patients with advanced urothelial carcinoma (aUC), either dose-reduced GC or gemcitabine/carboplatin (GCa) is an alternative option for “cispla...

    Authors: Kazuma Sugimoto, Satoru Taguchi, Kenjiro Kishitani, Taketo Kawai, Kazuki Masuda, Yu Nakamura, Manami Kinjo, Mitsuhiro Tambo, Jimpei Miyakawa, Yoshiyuki Akiyama, Yuta Yamada, Yusuke Sato, Daisuke Yamada, Tohru Nakagawa, Hiroshi Fukuhara and Haruki Kume
    Citation: BMC Urology 2022 22:177
    Content type: Research Published on:

  22. DNA methylation in cancer is considered a diagnostic and predictive biomarker. We investigated the usefulness of the methylation status of CALN1 as a biomarker for bladder cancer using methylation-sensitive restr...

    Authors: Kimiaki Takagi, Azumi Naruse, Kazutoshi Akita, Yuka Muramatsu-Maekawa, Kota Kawase, Takuya Koie, Masanobu Horie and Arizumi Kikuchi
    Citation: BMC Urology 2022 22:176
    Content type: Research Published on:

  23. This study aimed to evaluate the trend of adjuvant chemotherapy (AC) and neoadjuvant chemotherapy (NAC) in patients who underwent radical nephroureterectomy with bladder cuff excision (NUx) for upper tract uro...

    Authors: Jong Hyun Tae, Moon Soo Ha, Byung Hoon Chi, In Ho Chang, Tae-Hyoung Kim, Soon Chul Myung, Tuan Thanh Nguyen, Myoungsuk Kim, Kyung-Eun Lee, Yuwon Kim, Hyun-ki Woo, Dae-Sung Kyoung, Hasung Kim and Se Young Choi
    Citation: BMC Urology 2022 22:175
    Content type: Research Published on:

  24. Robot-assisted radical cystectomy (RARC) and intracorporeal urinary diversion are less invasive than conventional procedures. However, for older patients, cutaneous ureterostomy (CUS) may be preferred because ...

    Authors: Fumiya Kadoriku, Yutaro Sasaki, Kyotaro Fukuta, Yuichiro Atagi, Keito Shiozaki, Kei Daizumoto, Ryotaro Tomida, Yoshiteru Ueno, Megumi Tsuda, Yoshito Kusuhara, Tomoya Fukawa, Yutaka Yanagihara, Kunihisa Yamaguchi, Yasuyo Yamamoto, Hirofumi Izaki, Masayuki Takahashi…
    Citation: BMC Urology 2022 22:174
    Content type: Research Published on:

  25. We designed a new surgical procedure to treat benign prostatic hyperplasia(BPH). In order to verify its effectiveness and safety, we constructed this randomized controlled trial to compare the efficacy of our ...

    Authors: Zhengchao Liu, Zhipeng Chen, Dishi Yan, Tao Jiang, Jian Fu, Jun Zheng, Yuanxiu Zhou, Zhansong Zhou and Wenhao Shen
    Citation: BMC Urology 2022 22:173
    Content type: Research Published on:

  26. 5-α reductase inhibitors (5-ARIs) are first-line drugs for managing benign prostatic hyperplasia (BPH). Unfortunately, some patients do not respond to 5-ARI therapy and may even show ...

    Authors: Zhanliang Liu, Zhemin Lin, Fang Cao, Mingxin Jiang, Song jin, Yun Cui and YN Niu
    Citation: BMC Urology 2022 22:172
    Content type: Research Published on:

  28. Small cell bladder carcinoma (SCBC) is a rare and aggressive malignant tumor with no established treatment guidelines. Its treatment algorithm has been based on the small cell lung cancer (SCLC) guidelines. Me...

    Authors: Rei Kamitani, Toshiyuki Ando, Kazuya Hanai, Arihito Tanaka, Fumihiro Kashizaki, Yasutomo Sekido and Ryuichi Mizuno
    Citation: BMC Urology 2022 22:170
    Content type: Case report Published on:

  29. The aim of this study was to describe changes in patient-reported functional outcome measures (PROMs) comparing pre-treatment and 12 months after radical prostatectomy (RP), external beam radiation therapy (EB...

    Authors: Tenaw Tiruye, Michael O’Callaghan, Kim Moretti, Alex Jay, Braden Higgs, Kerry Santoro, Terry Boyle, Kerry Ettridge and Kerri Beckmann
    Citation: BMC Urology 2022 22:169
    Content type: Research Published on:

  30. The anti-carcinogenic properties of aspirin have been observed in some solid tumors. However, the molecular mechanism of therapeutic effects of aspirin on bladder cancer is still indistinct. We introduced a bi...

    Authors: Xiao Li, Yanghao Tai, Shuying Liu, Yating Gao, Kaining Zhang, Jierong Yin, Huijuan Zhang, Xia Wang, Xiaofei Li, Dongfeng Zhang and Dong-feng Zhang
    Citation: BMC Urology 2022 22:168
    Content type: Research Published on:

  32. Prostate cancer (PCa) is a common disease in men over 65 years of age, and should be detected early, while reducing unnecessary biopsies. This study aims to construct a classification and regression tree (CART...

    Authors: Nguyen Chi Cuong, Nguyen Truong Vien, Nguyen Minh Thien, Phan Thanh Hai and Tran Ngoc Dang
    Citation: BMC Urology 2022 22:166
    Content type: Research Published on:

  33. This study aimed to evaluate cosmetic outcomes and feasibility of transvaginal natural orifice specimen extraction (NOSE) in patients who underwent laparoscopic or robotic surgery for the treatment of benign o...

    Authors: Woo Yeon Hwang, Dong Hoon Suh and Sangchul Lee
    Citation: BMC Urology 2022 22:165
    Content type: Research Published on:

  34. To analyze grayscale values for hypoechoic lesions matched with target lesions evaluated using prebiopsy magnetic resonance imaging (MRI) according to the Prostate Imaging-Reporting and Data System (PI-RADS).

    Authors: Dong Gyun Kim, Jeong Woo Yoo, Kyo Chul Koo, Byung Ha Chung and Kwang Suk Lee
    Citation: BMC Urology 2022 22:164
    Content type: Research Published on:

  35. To evaluate and compare the outcome of ECIRS in the treatment of partial staghorn renal calculi in both prone split-leg positions versus GMSV positions with regard to; technical aspects, success rate, operativ...

    Authors: Tamer A. Abouelgreed, Mohamed A. Abdelaal, Moamen M. Amin, Adel Elatreisy, Osama Shalkamy, Abdrabuh M. Abdrabuh, Osama M. Ghoneimy and Hamdy Aboutaleb
    Citation: BMC Urology 2022 22:163
    Content type: Research Published on:

  36. Prostate cancer (PCa) is one of the most diagnosed cancers in the world. PCa inevitably progresses to castration-resistant prostate cancer (CRPC) after androgen deprivation therapy treatment, and castration-re...

    Authors: Yan Li, Hui Shi, Zhenjun Zhao and Minghui Xu
    Citation: BMC Urology 2022 22:162
    Content type: Research Published on:

  37. The original S.O.L.V.E. scoring system was modified using virtual reality technology, and a new H.L.P.E.S scoring system was constructed to improve the accuracy of predicting the stone-free rate after flexible...

    Authors: Jianglin Gu, Shengjun Luo, Li Jiang, Daixing Hu, Guozhi Zhao and Wei Tang
    Citation: BMC Urology 2022 22:161
    Content type: Research Published on:

  38. Cholelithiasis represents a known risk factor for digestive system neoplasm. Few studies reported the association between cholelithiasis and the risk of prostate cancer (PCa), and the results were controversial.

    Authors: Ya-Dong Li, Zheng-Ju Ren, Liang Gao, Jun-Hao Ma, Yuan-Qing Gou, Wei Tan and Chuan Liu
    Citation: BMC Urology 2022 22:160
    Content type: Research Published on:

  40. Laparoscopic adrenalectomy for pheochromocytoma is associated with high risk of intraoperative hemodynamic instability. Our study aimed to identify predictive factors for hemodynamic instability during laparos...

    Authors: Yong-sheng Huang, Lei Yan, Ze-yan Li, Zhi-qing Fang, Zhao Liu, Zhong-hua Xu and Gang-Li Gu
    Citation: BMC Urology 2022 22:158
    Content type: Research Published on:

  42. Bladder cancer (BC) seriously endangers public health, but effective biomarkers for BC diagnosis, particularly in the early stage, are still lacking. Identification of reliable biomarkers associated with early...

    Authors: Tao Fan, Liang Xue, Bingzheng Dong, Houguang He, Wenda Zhang, Lin Hao, Weiming Ma, Guanghui Zang, Conghui Han and Yang Dong
    Citation: BMC Urology 2022 22:156
    Content type: Research Published on:

  44. Emphysematous pyelonephritis (EPN) is a potentially life-threatening disease caused by a gas-producing necrotizing bacterial infection that involves the renal parenchyma, collecting system, and/or perinephric ...

    Authors: Xue Dong, Shuzong You, Huangqi Zhang, Dongnv Wang, Wenting Pan, Binhao Zhang, Shanqiang Huang, Xin Li, Jianxin Pang and Wenbin Ji
    Citation: BMC Urology 2022 22:154
    Content type: Case report Published on:

  45. For patients suffering from urinary retention due to neurogenic [e.g., spinal cord injury (SCI), spina bifida (SB), multiple sclerosis (MS)] or non-neurogenic [e.g., cancer, benign prostate hypertrophy (BPH)] ...

    Authors: Kim Bundvig Barken and Rikke Vaabengaard
    Citation: BMC Urology 2022 22:153
    Content type: Research Published on:

  46. Kidney renal papillary cell carcinoma (KIRP) is a dangerous cancer, which accounts for 15–20% of all kidney malignancies. Ferroptosis is a rare kind of cell death that overcomes medication resistance. Ferropto...

    Authors: Zixuan Wu, Xuyan Huang, Minjie Cai and Peidong Huang
    Citation: BMC Urology 2022 22:152
    Content type: Research Published on:

  47. The effect of enzalutamide in patients with non-metastatic castration-resistant prostate cancer after combined androgen blockade, which represents a patient profile similar to real-world clinical practice in J...

    Authors: Mikio Sugimoto, Takuma Kato, Yoichiro Tohi, Yosuke Shimizu, Ryuji Matsumoto, Takahiro Inoue, Yutaka Takezawa, Kimihiko Masui, Hiroshi Sasaki, Hiromi Hirama, Shiro Saito, Shin Egawa, Toshiyuki Kamoto, Satoshi Teramukai, Shinsuke Kojima, Takashi Kikuchi…
    Citation: BMC Urology 2022 22:151
    Content type: Research Published on:

  49. Testicular cancer (TC), due to its non-specific symptoms and occurrence in young men, is particularly dangerous. A critical point for early diagnosis is awareness of the disease and the willingness to perform ...

    Authors: Jakub Ryszawy, Maksymilian Kowalik, Jakub Wojnarowicz, Grzegorz Rempega, Michał Kępiński, Bartłomiej Burzyński, Paweł Rajwa, Andrzej Paradysz and Piotr Bryniarski
    Citation: BMC Urology 2022 22:149
    Content type: Research Published on:

  50. To investigate the value of computed tomography (CT)-based radiomics model analysis in differentiating renal oncocytoma (RO) from renal cell carcinoma subtypes (chromophobe renal cell carcinoma, clear cell car...

    Authors: Ziyang Yu, Jie Ding, Huize Pang, Hongkun Fang, Furong He, Chenxi Xu, Xuedan Li and Ke Ren
    Citation: BMC Urology 2022 22:147
    Content type: Research Published on:
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