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Figure 4 | BMC Urology

Figure 4

From: A mouse model for interstitial cystitis/painful bladder syndrome based on APF inhibition of bladder epithelial repair: a pilot study

Figure 4

Inhibition of zonula occludens type 1 (ZO-1) expression in CBA/J/Hsd mouse bladders following 14 days of treatment with as -APF. Bladder sections from mice treated with as-APF following bladder epithelial injury show decreased ZO-1 immunofluorescence staining (shown by small junctions between cells indicated by arrows) as compared to mice treated with PBS or inactive control nonglycosylated peptide. Representative data shown for the 3 mice in each treatment group from one experiment; experiment performed three times. (500X final magnification).

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