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Figure 3 | BMC Urology

Figure 3

From: Urinary levels of Hepatocarcinoma-intestine-pancreas/Pancreatitis-associated protein as a diagnostic biomarker in patients with bladder cancer

Figure 3

Urinary levels of HIP/PAP determined by the ELISA system. (A) Urinary HIP/PAP levels in BCa patients and controls. Bars represent median levels. The median urinary HIP/PAP concentration in BCa patients (median: 55.20 pg/mL, 25th and 75th percentiles: 11.91 and 150.96) was significantly higher than that in controls (median: 3.18 pg/mL, 25th and 75th percentiles: 0.00 and 8.28) (Mann–Whitney U test, P <0.0001). Asterisk indicates statistically significant P-values (P <0.05). (B) Correlation of urinary HIP/PAP levels in BCa patients with pathological stage. Patients were divided into four groups (Ta,T1,T2, ≥T3). The levels of urine HIP/PAP correlated proportionally with progression of T stage (Kruskal-Wallis test, P < 0.0001).

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