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Table 1 Clinical characteristics of laparoscopic radical prostatectomy cases treated with or without neoadjuvant hormonal therapy groups * p < 0.05

From: Neoadjuvant hormonal therapy is a feasible option in laparoscopic radical prostatectomy

Variables

LRP* alone

LRP with NHT**

No. of patients

270

72

Mean age ± SD

66.3 ± 6.1

67.7 ± 5.4

Mean serum PSA ± SD, ng/mL

8.64 ± 5.2

9.81 ± 4.1

Biopsy Gleason grade, n(%)

 ≤ 3 + 3

121 (44.8)

30 (41.7)

 3 + 4, 4 + 3

85 (31.5)

25 (34.7)

 ≥ 4 + 4

64 (23.7)

17 (23.6)

Clinical stage, n(%)

 cT1c

100 (37.0)

27 (37.5)

 cT2

170 (63.0)

45 (62.5)

D’Amico risk classification, n(%)

 low

76 (28.1)

14 (19.4)

 intermediate

74 (27.4)

24 (33.3)

 high

120 (44.4)

34 (47.2)

Pathological stage, n(%)

 pT2

193 (71.5)

62 (86.1)

 pT3

77 (28.5)

*10 (13.9)

Median operative time, min

260 (121–572)

276 (151–454)

Median blood loss, ml

600 (50–4500)

600 (90–3928)

Intraoperative complication

 Rectum injury, n(%)

4 (1.48)

2 (2.78)

 Blood transfusion, n(%)

4 (1.48)

2 (2.78)

 Open surgery conversion, n(%)

10 (3.70)

3 (4.17)

Positive surgical margin, n(%)

114 (42.2)

*20 (27.8)

Biochemical recurrence, n(%)

48 (17.8)

14 (19.4)

  1. Patient characteristics and outcomes in laparoscopic prostatectomy (LRP) only and LRP with neoadjuvant hormone therapy (NHT) *p < 0.05.
  2. LRP*: laparoscopic radical prostatectomy NHT**: neoadjuvant hormonal therapy.