Table 1 Levels of multiple cytokines at time of excessive leukocytosis (day 44) and after administration of cytoreductive drugs) (day 74) measured by ultiplex cytokine testing (Progen)
From: Severe paraneoplastic hypereosinophilia in metastatic renal cell carcinoma
Cytokine | Unit | Reference | Day 44 | Day 74 |
|---|---|---|---|---|
EGF | pg/ml | -780 | 201 | 15,8 |
Eotaxin | pg/ml | 175.8 ± 49.3 | 20,4 | 11,6 |
FGF-Basic | pg/ml | 1,5-6,0 | 40,8 | 23,5 |
G-CSF | pg/ml | 27.34 ± 8.00 | 93,5 | < LOW > |
GM-CSF | pg/ml | -2,3 | 40,6 | 19,8 |
HGF | pg/ml | 120 ± 120 | < HIGH > | 4480 |
IFN-a | pg/ml | 16.8 ± 6.59 | 25,3 | < LOW > |
IFNy | pg/ml | < LOW > | < LOW > | |
IL-10 | pg/ml | 9.2 ± 1.5 | 19,3 | 15,8 |
IL-12 p40/p70 | pg/ml | 171.1 ± 6,25 | 104 | 52,6 |
IL-13 | pg/ml | 25.5 ± 2.94 | 35,7 | < LOW > |
IL-15 | pg/ml | 16.2 ± 4.0 | < LOW > | 45,2 |
IL-17 | pg/ml | 0-127 | 28,8 | 23,6 |
IL-1b | pg/ml | 40.2 ± 8.78 | 25,7 | 12,5 |
IL-1RA | pg/ml | 189 ± 22 | 979 | 241 |
IL-2 | pg/ml | 2.4 ± 0.8 | 9,16 | 6,01 |
IL-2R | pg/ml | 426.5 ± 22.4 | 12300 | 18300 |
IL-4 | pg/ml | 3.34 ± 0.84 | 35,8 | < LOW > |
IL-5 | pg/ml | < LOW > | < LOW > | |
IL-6 | pg/ml | 22.8 ± 7 | 330 | 299 |
IL-7 | pg/ml | 66,4 | 47 | |
IL-8 | pg/ml | 9.56 ± 0.4 | 652 | 111 |
IP-10 | pg/ml | 4.5-27.1 | 73,6 | 27,3 |
MCP-1 | pg/ml | 173.2 ± 15.04 | 1110 | 377 |
MIG | pg/ml | 22.1-52.4 | < LOW > | < LOW > |
MIP-1a | pg/ml | 88.1 ± 14.31 | 179 | 45,8 |
MIP-1b | pg/ml | 135.1 ± 29.22 | 2640 | 278 |
RANTES | pg/ml | 1100-4360 | 3750 | 664 |
TNFa | pg/ml | 34.32 ± 11.46 | 9,21 | 5,81 |
VEGF | pg/ml | 76.6 ± 6.07 | 65,5 | 24,1 |