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Table 1 Levels of multiple cytokines at time of excessive leukocytosis (day 44) and after administration of cytoreductive drugs) (day 74) measured by ultiplex cytokine testing (Progen)

From: Severe paraneoplastic hypereosinophilia in metastatic renal cell carcinoma

Cytokine Unit Reference Day 44 Day 74
EGF pg/ml -780 201 15,8
Eotaxin pg/ml 175.8 ± 49.3 20,4 11,6
FGF-Basic pg/ml 1,5-6,0 40,8 23,5
G-CSF pg/ml 27.34 ± 8.00 93,5 < LOW >
GM-CSF pg/ml -2,3 40,6 19,8
HGF pg/ml 120 ± 120 < HIGH > 4480
IFN-a pg/ml 16.8 ± 6.59 25,3 < LOW >
IFNy pg/ml   < LOW > < LOW >
IL-10 pg/ml 9.2 ± 1.5 19,3 15,8
IL-12 p40/p70 pg/ml 171.1 ± 6,25 104 52,6
IL-13 pg/ml 25.5 ± 2.94 35,7 < LOW >
IL-15 pg/ml 16.2 ± 4.0 < LOW > 45,2
IL-17 pg/ml 0-127 28,8 23,6
IL-1b pg/ml 40.2 ± 8.78 25,7 12,5
IL-1RA pg/ml 189 ± 22 979 241
IL-2 pg/ml 2.4 ± 0.8 9,16 6,01
IL-2R pg/ml 426.5 ± 22.4 12300 18300
IL-4 pg/ml 3.34 ± 0.84 35,8 < LOW >
IL-5 pg/ml   < LOW > < LOW >
IL-6 pg/ml 22.8 ± 7 330 299
IL-7 pg/ml   66,4 47
IL-8 pg/ml 9.56 ± 0.4 652 111
IP-10 pg/ml 4.5-27.1 73,6 27,3
MCP-1 pg/ml 173.2 ± 15.04 1110 377
MIG pg/ml 22.1-52.4 < LOW > < LOW >
MIP-1a pg/ml 88.1 ± 14.31 179 45,8
MIP-1b pg/ml 135.1 ± 29.22 2640 278
RANTES pg/ml 1100-4360 3750 664
TNFa pg/ml 34.32 ± 11.46 9,21 5,81
VEGF pg/ml 76.6 ± 6.07 65,5 24,1
  1. Low = concentration below detection limit, High = above detection limit. Reference values were obtained from [57]