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Table 3 Univariate and multivariate analyses for overall survival

From: Prognostic benefit of surgical management in renal cell carcinoma patients with thrombus extending to the renal vein and inferior vena cava: 17-year experience at a single center

Ā 

All

RV thrombus group

IVC thrombus group

Ā 

Univariate

Multivariate

Univariate

Multivariate

Univariate

Multivariate

Independent factors

P value

HR

95.0% CI

P value

HR

95.0% CI

P value

HR

95.0% CI

P value

HR

95.0% CI

P value

HR

95.0% CI

P value

HR

95.0% CI

Age

0.875

0.997

0.972-1.024

Ā Ā Ā 

0.645

1.013

0.958-1.072

Ā Ā Ā 

0.877

1.002

0.974-1.032

Ā Ā Ā 

ECOG-Performance status

0.002

1.433

1.151-1.869

Ā Ā Ā 

0.045

1.776

1.012-3.115

Ā Ā Ā 

0.063

1.297

0.986-1.704

Ā Ā Ā 

Gender (ref, female)

0.073

0.576

1.315-1.053

Ā Ā Ā 

0.018

0.234

0.070-0.776

Ā Ā Ā 

0.086

0.860

0.414-1.787

Ā Ā Ā 

Thrombus level (ref, renal vein)

0.000

1.472

1.185-1.830

0.034

1.275

1.0181.599

Ā Ā Ā Ā Ā Ā 

0.179

1.315

0.882-1.960

Ā Ā Ā 

Distant metastasis (ref, without metastasis)

0.000

4.115

2.020-8.384

0.019

2.548

1.168-5.560

0.003

9.673

2.113-44.27

0.000

34.01

5.368-215.6

0.094

1.996

0.888-4.4483

Ā Ā Ā 

Underwent surgery (ref, not performed)

0.000

0.144

0.069-0.303

0.000

0.239

0.108-0.532

0.008

0.180

0.051-0.636

Ā Ā Ā 

0.000

0.105

0.036-0.305

0.000

0.061

0.016-0.230

Hemoglobin (g/dL)

0.002

0.807

0.704-0.926

Ā Ā Ā 

0.005

0.645

0.477-0.873

0.002

0.500

0.323-0.775

0.056

0.863

0.742-1.004

Ā Ā Ā 

Serum albumin (g/dL)

0.003

0.487

0.306-0.778

0.026

0.849

0.736-0.980

0.124

0.537

0.244-1.186

Ā Ā Ā 

0.004

0.408

0.221-0.756

0.002

0.250

0.104-0.600

eGFR (ml/min./1.73Ā m2)

0.190

0.989

0.974-1.005

Ā Ā Ā 

0.470

0.989

0.961-1.019

Ā Ā Ā 

0.494

0.999

0.995-1.002

Ā Ā Ā 

Choline esterase (U/L)

0.052

0.996

0.994-1.000

0.023

0.995

0.992-0.999

0.156

0.996

0.991-1.002

Ā Ā Ā 

0.002

1.407

1.137-1.740

0.053

1.282

0.996-1.648

Neutrophil-lymphocyte ratio

0.007

1.297

1.072-1.571

0.021

1.250

1.034-1.513

0.387

1.204

0.791-1.835

Ā Ā Ā 

0.002

1.407

1.137-1.740

0.053

1.282

0.993-1.648

Serum sodium (mEq/L)

0.001

0.814

0.721-0.921

Ā Ā Ā 

0.006

0.774

0.644-0.931

Ā Ā Ā 

0.090

0.862

0.723-1.023

Ā Ā Ā 

Correlated calcium (mg/dL)

0.322

1.143

0.877-1.491

Ā Ā Ā 

0.109

1.982

0.858-4.579

Ā Ā Ā 

0.439

0.854

0.572-1.274

0.038

0.598

0.368-0.973

Lactate dehydrogenase (LDH, IU/L)

0.000

1.004

1.002-1.006

Ā Ā Ā 

0.071

1.004

1.001-1.008

Ā Ā Ā 

0.019

1.003

1.001-1.006

Ā Ā Ā 

C-reactive protein (CRP, mg/dL)

0.044

1.046

1.001-1.093

Ā Ā Ā 

0.032

1.083

1.007-1.165

Ā Ā Ā 

0.299

1.029

0.975-1.0865

Ā Ā Ā 

Charlson comorbidity index

0.000

1.258

1.130-1.401

0.006

1.196

1.053-1.360

0.002

1.442

1.144-1.818

Ā Ā Ā 

0.022

1.152

1.020-1.3007

Ā Ā Ā 

Molecular targeted agents (ref, not used)

0.704

1.148

0.561-2.351

Ā Ā Ā 

0.661

0.711

0.155-3.275

Ā Ā Ā 

0.466

1.362

0.593-3.124

Ā Ā Ā