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Table 3 Percentage of patients using OAB-related concomitant medications during follow-up by antimuscarinic drug

From: Health economics perspective of fesoterodine, tolterodine or solifenacin as first-time therapy for overactive bladder syndrome in the primary care setting in Spain

Concomitant medication

Antimuscarinic

  
 

Fesoterodine

Solifenacin

Tolterodine

Overall

Overall

 

(n = 302)

(n = 952)

(n = 717)

(N = 1971)

PValue*

Antidepressants

31.8

42.6

57.9†‡

45.6

<0.001

Tricyclics

9.2

9.1

7.4

8.6

0.610

SSRIs

16.9

23.3§

35.5†‡

26.1

<0.001

SNRIs

18.5

26.3

37.4†‡

28.5

<0.001

Benzodiazepines/hypnotics

49.2

53.5

58.1§

54.2

0.012

Antibiotics/antiseptics

20.5

20.4

35.5†‡

25.2

<0.001

Laxatives

19.5

21.9

23.0

21.8

0.638

Dermatological products

21.5

21.8

20.2

21.2

0.847

  1. SSRIs = selective serotonin reuptake inhibitors; SNRIs = serotonin-norepinephrine reuptake inhibitors.
  2. *Controlling for location, age, sex, medication possession ratio, time since diagnosis and Charlson co-morbidity index.
  3. P < 0.001 vs fesoterodine.
  4. P < 0.001 vs solifenacin.
  5. § P < 0.05 vs fesoterodine.
  6. P < 0.01 vs fesoterodine.